ALLMedicine™ Bleeding Disorders Center

Mar 17th, 2023 - The future bleeding risk, especially after hemostatic challenges, and thus requirement of hemostatic treatment in patients with mild-to-moderate bleeding disorders (MBD) is largely unknown. To prospectively examine the recurrence of bleeding sympt...

Mar 16th, 2023 - The objective of this study was to identify factors independently associated with complications, hospital readmission, reoperation, and death in the 30-day period after surgical treatment of isolated olecranon fractures. A retrospective case-contr...

Mar 16th, 2023 - The National Hemophilia Foundation State of the Science Research Summit initiative sought to unify research efforts in the US inherited bleeding disorders (BDs) community around key topics of importance to people living with inherited BDs, the liv...

Mar 16th, 2023 - The National Hemophilia Foundation's State of the Science Research Summit: the foundation of a national research blueprint for inherited bleeding disorders.|2023|Valentino LA,Witkop ML,Santaella ME,DiMichele D,Recht M,|

Mar 16th, 2023 - Decades of research have transformed hemophilia from severely limiting children's lives to a manageable disorder compatible with a full, active life, for many in high-income countries. The direction of future research will determine whether exciti...

Jan 22nd, 2019 - This paper sets out good practice for clinicians involved in interpreting variant reports for patients with inherited bleeding disorders. It is aimed primarily at doctors, nurses and allied healthcare professionals who may not have had specific tr...

Feb 16th, 2018 - The prevalence of bleeding disorders, notably von Willebrand disease (vWD), among adult women with objectively documented menorrhagia is consistently reported to be 10% to 20% and is even higher in adolescents presenting with menorrhagia. Diagnost...

Oct 29th, 2014 - Principles of treatment and update of recommendations for the management of haemophilia and congenital bleeding disorders in Italy.|2014|Rocino A,Coppola A,Franchini M,Castaman G,Santoro C,|blood,genetics,pathology,therapy,

Dec 3rd, 2011 - This guideline supersedes a prior one from 2007 on a similar topic. The work group evaluated the available literature concerning various aspects of patient screening, risk factor assessment, and prophylactic treatment against venous thromboembolic...

Jul 28th, 2011 - The guideline writing group was selected to be representative of UK-based medical experts. MEDLINE was systematically searched for publications in English up to the Summer of 2010 using key words platelet, platelet function testing and platelet ag...

Mar 10th, 2023 - Background Hematological diseases are disorders of the blood and hematopoietic organs. The current hematological cohorts are mostly based on single-center or multi-center cases, or cohorts with limited sample size in China. There is a lack of comp...

Mar 3rd, 2023 - Background: -NIH and FDA intramural investigators performing in vitro studies involving human blood components have a need for a steady, reliable, consistent source of these blood components, preferably derived from screened donors documented to b...

Mar 1st, 2023 - Von Willebrand Disease (VWD) is the most common inherited bleeding disorder affecting up to 0.1% of the population, is usually characterized by mucocutaneous bleeding, HMB, surgical bleeding or other hemostatic challenges. VWD currently has few th...

Feb 14th, 2023 - The aim of the study is the systematic scientific evaluation of a standardized questionnaire for bleeding history already used in clinical routine during the preoperative anesthesiological visit and its impact on perioperative coagulation manageme...

Jan 30th, 2023 - The study design is a prospective randomized control trial done in a single institution from 2021 to 2022. Approval from the institutional ethics committee was obtained for the study (number 04/21). Major surgery was defined as "surgeries involvin...

Nov 1st, 2022 - When assessing monoclonal gammopathy it is important to rule out clinically significant associations requiring treatment. On initial patient consultation, gathering a detailed patient history and thorough physical exam can catch clinically signifi...

Sep 20th, 2022 - In some cases, bruising or bleeding from bleeding disorders may look like signs of child abuse, but new guidance may help clinicians distinguish one from the other. On Sept. 19 the American Academy of Pediatrics published two reports — a clinical ...

Sep 19th, 2022 - In some cases, bruising or bleeding from bleeding disorders may look like signs of child abuse, but new guidance may help clinicians distinguish one from the other. On Sept.

Aug 5th, 2022 - A wide range of symptoms and conditions cropped up in children and adolescents in the year after a COVID-19 infection, though they were seemingly spared from mental and breathing issues, a CDC study reported. Compared with peers not diagnosed with...

Jun 3rd, 2022 - Robert Alter, MD: We’re going to start by discussing the therapy options that I thought about using. We’re blessed to have several options of first-line systemic therapy utilizing an I/O [immuno-oncology]–TKI [tyrosine kinase inhibitor] regimen. A...