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About 238 results

ALLMedicine™ Factor V Deficiency Center

Research & Reviews  119 results

A novel mutation (Ser951LeufsTer8) in F5 gene leads to hereditary coagulation factor V ...
https://doi.org/10.1097/MBC.0000000000001003
Blood Coagulation & Fibrinolysis : an International Journ... Su K, Wang L et. al.

Jan 14th, 2021 - The current study aims to explore the phenotype and genotype of a novel mutation (Ser951LeufsTer8) of F5 gene combined with polymorphism (R485K) in a family of hereditary coagulation factor V deficiency. The factor V activity and antigen were test...

Analysis of phenotype and genotype of a family with hereditary coagulation factor V def...
https://doi.org/10.1097/MBC.0000000000000946
Blood Coagulation & Fibrinolysis : an International Journ... Luo S, Liu S et. al.

Aug 24th, 2020 - : To analyze the causative gene and the molecular pathogenesis in a pedigree with compound hereditary coagulation factor V deficiency. Routine blood coagulation indexes and factor V antigen (FV:Ag) were detected by the one-stage clotting method an...

Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-me...
https://doi.org/10.1111/hae.14104
Haemophilia : the Official Journal of the World Federatio... Nakamura T, Morishige S et. al.

Jul 23rd, 2020 - Factor V (FV) deficiency is a monogenic inherited coagulation disorder considered to be an ideal indication for gene therapy. To investigate the possibility of therapeutic application of genome editing, we generated induced pluripotent stem cells ...

Congenital factor V deficiency from compound heterozygous mutations with a novel varian...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004762
Medicine Park CH, Park MS et. al.

Jan 31st, 2020 - Congenital factor V deficiency (FVD) is a rare bleeding disorder characterized by low or undetectable plasma factor V (FV) levels leading to mild to severe bleeding symptoms. Currently, more than 100 mutations have been reported in F5. We herein r...

Factor V Deficiency
https://emedicine.medscape.com/article/209492-overview

Dec 30th, 2019 - Background Factor V is an essential component in the blood coagulation cascade. Inherited or acquired deficiencies in factor V are rare causes of bleeding disorders. [1, 2] Factor V deficiency is also known as Owren disease. Dr. Paul Owren identif...

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Clinicaltrials.gov  119 results

A novel mutation (Ser951LeufsTer8) in F5 gene leads to hereditary coagulation factor V ...
https://doi.org/10.1097/MBC.0000000000001003
Blood Coagulation & Fibrinolysis : an International Journ... Su K, Wang L et. al.

Jan 14th, 2021 - The current study aims to explore the phenotype and genotype of a novel mutation (Ser951LeufsTer8) of F5 gene combined with polymorphism (R485K) in a family of hereditary coagulation factor V deficiency. The factor V activity and antigen were test...

Analysis of phenotype and genotype of a family with hereditary coagulation factor V def...
https://doi.org/10.1097/MBC.0000000000000946
Blood Coagulation & Fibrinolysis : an International Journ... Luo S, Liu S et. al.

Aug 24th, 2020 - : To analyze the causative gene and the molecular pathogenesis in a pedigree with compound hereditary coagulation factor V deficiency. Routine blood coagulation indexes and factor V antigen (FV:Ag) were detected by the one-stage clotting method an...

Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-me...
https://doi.org/10.1111/hae.14104
Haemophilia : the Official Journal of the World Federatio... Nakamura T, Morishige S et. al.

Jul 23rd, 2020 - Factor V (FV) deficiency is a monogenic inherited coagulation disorder considered to be an ideal indication for gene therapy. To investigate the possibility of therapeutic application of genome editing, we generated induced pluripotent stem cells ...

Congenital factor V deficiency from compound heterozygous mutations with a novel varian...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004762
Medicine Park CH, Park MS et. al.

Jan 31st, 2020 - Congenital factor V deficiency (FVD) is a rare bleeding disorder characterized by low or undetectable plasma factor V (FV) levels leading to mild to severe bleeding symptoms. Currently, more than 100 mutations have been reported in F5. We herein r...

Factor V Deficiency
https://emedicine.medscape.com/article/209492-overview

Dec 30th, 2019 - Background Factor V is an essential component in the blood coagulation cascade. Inherited or acquired deficiencies in factor V are rare causes of bleeding disorders. [1, 2] Factor V deficiency is also known as Owren disease. Dr. Paul Owren identif...

see more →