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About 1,965 results

ALLMedicine™ Factor XIII Center

Research & Reviews  973 results

Acquired FXIII deficiency is associated with high morbidity.
https://doi.org/10.1055/a-1481-2733
Thrombosis and Haemostasis; Duque P, Chasco-Ganuza M et. al.

Apr 14th, 2021 - A factor XIII (FXIII) level >30% is considered necessary to prevent spontaneous bleeding. Bleeding is also a risk in patients with acquired FXIII deficiency, but the hemostatic level of FXIII in this context remains to be determined. We retrospect...

Pathological coagulation parameters in as many as 54 patients with autoimmune acquired ...
https://doi.org/10.1111/hae.14298
Haemophilia : the Official Journal of the World Federatio... Ichinose A, Osaki T et. al.

Apr 13th, 2021 - Autoimmune factor XIII (FXIII) deficiency (AiF13D) due to anti-FXIII autoantibodies is an extremely rare, life-threatening bleeding disorder that mostly occurs in the elderly. The number of patients diagnosed with AiF13D has been increasing in Jap...

Effects of pathogen reduction technology and storage duration on the ability of cryopre...
https://doi.org/10.1111/trf.16376
Transfusion Thomas KA, Shea SM et. al.

Mar 23rd, 2021 - Fibrinogen concentrates and cryoprecipitate are currently used for fibrinogen supplementation in bleeding patients with dysfibrinogenemia. Both products provide an abundant source of fibrinogen but take greater than 10 min to prepare for administr...

COVID-19 is Associated with an Acquired Factor XIII Deficiency.
https://doi.org/10.1055/a-1450-8414
Thrombosis and Haemostasis; von Meijenfeldt FA, Havervall S et. al.

Mar 20th, 2021 - COVID-19 is Associated with an Acquired Factor XIII Deficiency.|2021|von Meijenfeldt FA,Havervall S,Adelmeijer J,Lundström A,Magnusson M,|

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Drugs  4 results see all →

Clinicaltrials.gov  983 results

Acquired FXIII deficiency is associated with high morbidity.
https://doi.org/10.1055/a-1481-2733
Thrombosis and Haemostasis; Duque P, Chasco-Ganuza M et. al.

Apr 14th, 2021 - A factor XIII (FXIII) level >30% is considered necessary to prevent spontaneous bleeding. Bleeding is also a risk in patients with acquired FXIII deficiency, but the hemostatic level of FXIII in this context remains to be determined. We retrospect...

Pathological coagulation parameters in as many as 54 patients with autoimmune acquired ...
https://doi.org/10.1111/hae.14298
Haemophilia : the Official Journal of the World Federatio... Ichinose A, Osaki T et. al.

Apr 13th, 2021 - Autoimmune factor XIII (FXIII) deficiency (AiF13D) due to anti-FXIII autoantibodies is an extremely rare, life-threatening bleeding disorder that mostly occurs in the elderly. The number of patients diagnosed with AiF13D has been increasing in Jap...

Effects of pathogen reduction technology and storage duration on the ability of cryopre...
https://doi.org/10.1111/trf.16376
Transfusion Thomas KA, Shea SM et. al.

Mar 23rd, 2021 - Fibrinogen concentrates and cryoprecipitate are currently used for fibrinogen supplementation in bleeding patients with dysfibrinogenemia. Both products provide an abundant source of fibrinogen but take greater than 10 min to prepare for administr...

COVID-19 is Associated with an Acquired Factor XIII Deficiency.
https://doi.org/10.1055/a-1450-8414
Thrombosis and Haemostasis; von Meijenfeldt FA, Havervall S et. al.

Mar 20th, 2021 - COVID-19 is Associated with an Acquired Factor XIII Deficiency.|2021|von Meijenfeldt FA,Havervall S,Adelmeijer J,Lundström A,Magnusson M,|

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News  5 results

FXIII replacement may improve hemostasis in acquired hemophilia A
https://www.mdedge.com/hematology-oncology/article/196298/bleeding-disorders/fxiii-replacement-may-improve-hemostasis?channel=27970
Caleb Rans

Mar 13th, 2019 - Measurement of factor XIII levels, followed by replacing deficiencies if found, may help to achieve sustained hemostasis in the management of bleeding in patients with acquired hemophilia A. Jameel Abdulrehman, MD, of the University of Toronto in.

Children under 6 with factor XIII deficiency had no major bleeds with recombinant product
https://www.mdedge.com/familymedicine/article/110923/bleeding-disorders/children-under-6-factor-xiii-deficiency-had-no
Hematology News; Neil Osterweil

Jul 28th, 2016 - ORLANDO –A recombinant form of factor XIII was effective at preventing serious bleeding episodes in young children with factor XIII-A subunit deficiency, a rare and serious bleeding disorder. In a small international phase III trial, there were no.

Use of topical hemostatic agents in gynecologic surgery
https://www.mdedge.com/hematology-oncology/article/89443/gynecologic-cancer/use-topical-hemostatic-agents-gynecologic/page/0/1

Dec 16th, 2014 - Topical thrombins Thrombin (Thrombin-JMI, Evithrom, Recothrom) is derived from bovine, human, or recombinant sources. It converts fibrinogen to fibrin and activates factor XIII, platelets, and smooth muscle constriction (Biologics 2008;2:593-9).

Factor affects thrombus size and content
https://www.mdedge.com/hematology-oncology/article/186765/thrombosis/factor-affects-thrombus-size-and-content
HT Staff

Jul 8th, 2014 - Thrombus Credit: Kevin MacKenzie The activity of transglutaminase factor XIII is critical for retaining red blood cells in a thrombus and therefore affects the clot’s size, investigators have reported in the Journal of Clinical Investigation. The.

FDA Approves First Treatment for Congenital Factor XIII Deficiency
https://www.medscape.com/viewarticle/737875

Feb 22nd, 2011 - February 23, 2011 — The first product intended to prevent bleeding in people with congenital factor XIII deficiency has been approved by the US Food and Drug Administration (FDA). Corifact, manufactured by CSL Behring, received orphan drug designa...

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