ALLMedicine™ Factor XIII Center

May 5th, 2021 - Immunoglobulin A (IgA) vasculitis mainly affects the joints, skin, kidneys, and gastrointestinal tract; however, purpura is an essential diagnostic criterion. Here, we report an unusual case of IgA vasculitis without purpura in an elderly woman. A...

Apr 14th, 2021 - A factor XIII (FXIII) level >30% is considered necessary to prevent spontaneous bleeding. Bleeding is also a risk in patients with acquired FXIII deficiency, but the hemostatic level of FXIII in this context remains to be determined. We retrospect...

Apr 13th, 2021 - Autoimmune factor XIII (FXIII) deficiency (AiF13D) due to anti-FXIII autoantibodies is an extremely rare, life-threatening bleeding disorder that mostly occurs in the elderly. The number of patients diagnosed with AiF13D has been increasing in Jap...

Mar 23rd, 2021 - Fibrinogen concentrates and cryoprecipitate are currently used for fibrinogen supplementation in bleeding patients with dysfibrinogenemia. Both products provide an abundant source of fibrinogen but take greater than 10 min to prepare for administr...

Mar 20th, 2021 - COVID-19 is Associated with an Acquired Factor XIII Deficiency.|2021|von Meijenfeldt FA,Havervall S,Adelmeijer J,Lundström A,Magnusson M,|

May 5th, 2021 - Immunoglobulin A (IgA) vasculitis mainly affects the joints, skin, kidneys, and gastrointestinal tract; however, purpura is an essential diagnostic criterion. Here, we report an unusual case of IgA vasculitis without purpura in an elderly woman. A...

Apr 14th, 2021 - A factor XIII (FXIII) level >30% is considered necessary to prevent spontaneous bleeding. Bleeding is also a risk in patients with acquired FXIII deficiency, but the hemostatic level of FXIII in this context remains to be determined. We retrospect...

Apr 13th, 2021 - Autoimmune factor XIII (FXIII) deficiency (AiF13D) due to anti-FXIII autoantibodies is an extremely rare, life-threatening bleeding disorder that mostly occurs in the elderly. The number of patients diagnosed with AiF13D has been increasing in Jap...

Mar 23rd, 2021 - Fibrinogen concentrates and cryoprecipitate are currently used for fibrinogen supplementation in bleeding patients with dysfibrinogenemia. Both products provide an abundant source of fibrinogen but take greater than 10 min to prepare for administr...

Mar 20th, 2021 - COVID-19 is Associated with an Acquired Factor XIII Deficiency.|2021|von Meijenfeldt FA,Havervall S,Adelmeijer J,Lundström A,Magnusson M,|

Mar 13th, 2019 - Measurement of factor XIII levels, followed by replacing deficiencies if found, may help to achieve sustained hemostasis in the management of bleeding in patients with acquired hemophilia A. Jameel Abdulrehman, MD, of the University of Toronto in.

Jul 28th, 2016 - ORLANDO –A recombinant form of factor XIII was effective at preventing serious bleeding episodes in young children with factor XIII-A subunit deficiency, a rare and serious bleeding disorder. In a small international phase III trial, there were no.

Dec 16th, 2014 - Topical thrombins Thrombin (Thrombin-JMI, Evithrom, Recothrom) is derived from bovine, human, or recombinant sources. It converts fibrinogen to fibrin and activates factor XIII, platelets, and smooth muscle constriction (Biologics 2008;2:593-9).

Jul 8th, 2014 - Thrombus Credit: Kevin MacKenzie The activity of transglutaminase factor XIII is critical for retaining red blood cells in a thrombus and therefore affects the clot’s size, investigators have reported in the Journal of Clinical Investigation. The.

Feb 22nd, 2011 - February 23, 2011 — The first product intended to prevent bleeding in people with congenital factor XIII deficiency has been approved by the US Food and Drug Administration (FDA). Corifact, manufactured by CSL Behring, received orphan drug designa...