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About 4,360 results

ALLMedicine™ Von Willebrand Disease Center

Research & Reviews  2,095 results

Von Willebrand disease: What does the future hold?
https://doi.org/10.1182/blood.2020008501
Blood Denis CV, Susen S et. al.

Mar 4th, 2021 - Von Willebrand disease (VWD) is characterized by its heterogeneous clinical manifestation, which complicates its diagnosis and management. The clinical management of VWD has remained essentially unchanged over the last 30 years or so, using von Wi...

Toward Personalized Treatment for Patients with Low von Willebrand Factor and Quantitat...
https://doi.org/10.1055/s-0041-1722864
Seminars in Thrombosis and Hemostasis; O'Donnell JS

Feb 26th, 2021 - The biological mechanisms involved in the pathogenesis of type 2 and type 3 von Willebrand disease (VWD) have been studied extensively. In contrast, although accounting for the majority of VWD cases, the pathobiology underlying partial quantitativ...

Type 2B von Willebrand Disease in Pregnancy: A Systematic Literature Review.
https://doi.org/10.1055/s-0041-1723799
Seminars in Thrombosis and Hemostasis; Makhamreh MM, Russo ML et. al.

Feb 26th, 2021 - Our objective was to review the maternal characteristics and obstetric complications in women with type 2B von Willebrand disease (VWD). A systematic literature search was conducted using PubMed, Scopus, Cochrane Central Register of Controlled Tri...

Current Challenges in the Peripartum Management of Women with von Willebrand Disease.
https://doi.org/10.1055/s-0041-1723797
Seminars in Thrombosis and Hemostasis; Byrne B, Ryan K et. al.

Feb 26th, 2021 - For many women, pregnancy and childbirth represent their first major hemostatic challenges. Despite advancements in obstetric care, up to 2 to 5% of all deliveries are complicated by postpartum hemorrhage (PPH). To mitigate bleeding risk, physiolo...

Giving von Willebrand disease the attention it deserves.
https://doi.org/10.1016/S2352-3026(21)00031-4
The Lancet. Haematology; The Lancet Haematology

Feb 26th, 2021 - Giving von Willebrand disease the attention it deserves.|2021|The Lancet Haematology ,|

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Guidelines  9 results

No. 163-Gynaecological and Obstetric Management of Women With Inherited Bleeding Disord...
https://doi.org/10.1016/j.jogc.2017.11.036
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Demers C, Derzko C et. al.

Feb 15th, 2018 - The prevalence of bleeding disorders, notably von Willebrand disease (vWD), among adult women with objectively documented menorrhagia is consistently reported to be 10% to 20% and is even higher in adolescents presenting with menorrhagia. Diagnost...

Evidence-based recommendations on the treatment of von Willebrand disease in Italy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689066
Blood Transfusion = Trasfusione Del Sangue; Mannucci PM, Franchini M et. al.

Jun 8th, 2009 - von Willebrand disease (VWD) is the most common hereditary bleeding disorder affecting both males and females. It arises from quantitative or qualitative defects of von Willebrand factor (VWF) and causes bleeding of mucous membranes and soft tissu...

Clinical and laboratory diagnosis of von Willebrand disease: a synopsis of the 2008 NHL...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592788
American Journal of Hematology; Nichols WL, Rick ME et. al.

May 5th, 2009 - Von Willebrand factor (VWF) mediates blood platelet adhesion and accumulation at sites of blood vessel injury, and also carries coagulation factor VIII (FVIII) that is important for generating procoagulant activity. Von Willebrand disease (VWD), t...

The molecular analysis of von Willebrand disease: a guideline from the UK Haemophilia C...
https://doi.org/10.1111/j.1365-2516.2008.01813.x
Haemophilia : the Official Journal of the World Federatio... Keeney S, Bowen D et. al.

Jul 21st, 2008 - von Willebrand disease (VWD) is a common autosomally inherited bleeding disorder associated with mucosal or trauma-related bleeding in affected individuals. VWD results from a quantitative or qualitative deficiency of von Willebrand factor (VWF), ...

von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the N...
https://doi.org/10.1111/j.1365-2516.2007.01643.x
Haemophilia : the Official Journal of the World Federatio... Nichols WL, Hultin MB et. al.

Mar 4th, 2008 - von Willebrand disease (VWD) is a commonly encountered inherited bleeding disorder affecting both males and females, causing mucous membrane and skin bleeding symptoms, and bleeding with surgical or other haemostatic challenges. VWD may be disprop...

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Drugs  33 results see all →

Clinicaltrials.gov  2,157 results

Von Willebrand disease: What does the future hold?
https://doi.org/10.1182/blood.2020008501
Blood Denis CV, Susen S et. al.

Mar 4th, 2021 - Von Willebrand disease (VWD) is characterized by its heterogeneous clinical manifestation, which complicates its diagnosis and management. The clinical management of VWD has remained essentially unchanged over the last 30 years or so, using von Wi...

Toward Personalized Treatment for Patients with Low von Willebrand Factor and Quantitat...
https://doi.org/10.1055/s-0041-1722864
Seminars in Thrombosis and Hemostasis; O'Donnell JS

Feb 26th, 2021 - The biological mechanisms involved in the pathogenesis of type 2 and type 3 von Willebrand disease (VWD) have been studied extensively. In contrast, although accounting for the majority of VWD cases, the pathobiology underlying partial quantitativ...

Type 2B von Willebrand Disease in Pregnancy: A Systematic Literature Review.
https://doi.org/10.1055/s-0041-1723799
Seminars in Thrombosis and Hemostasis; Makhamreh MM, Russo ML et. al.

Feb 26th, 2021 - Our objective was to review the maternal characteristics and obstetric complications in women with type 2B von Willebrand disease (VWD). A systematic literature search was conducted using PubMed, Scopus, Cochrane Central Register of Controlled Tri...

Current Challenges in the Peripartum Management of Women with von Willebrand Disease.
https://doi.org/10.1055/s-0041-1723797
Seminars in Thrombosis and Hemostasis; Byrne B, Ryan K et. al.

Feb 26th, 2021 - For many women, pregnancy and childbirth represent their first major hemostatic challenges. Despite advancements in obstetric care, up to 2 to 5% of all deliveries are complicated by postpartum hemorrhage (PPH). To mitigate bleeding risk, physiolo...

Giving von Willebrand disease the attention it deserves.
https://doi.org/10.1016/S2352-3026(21)00031-4
The Lancet. Haematology; The Lancet Haematology

Feb 26th, 2021 - Giving von Willebrand disease the attention it deserves.|2021|The Lancet Haematology ,|

see more →

News  59 results

Fast Five Quiz: Bleeding Disorders
https://reference.medscape.com/viewarticle/915458

Jul 10th, 2019 - Bleeding disorders are conditions in which an individual's blood does not properly clot. Although hemophilia is perhaps the most well-known bleeding disorder, it is somewhat rare. Although it is typically less severe than other similar conditions,...

Fast Five Quiz: Bleeding Disorders
https://reference.medscape.com/viewarticle/915458_1

Jul 10th, 2019 - Bleeding disorders are conditions in which an individual's blood does not properly clot. Although hemophilia is perhaps the most well-known bleeding disorder, it is somewhat rare. Although it is typically less severe than other similar conditions,...

Need for VWF concentrate therapy appears low
https://www.mdedge.com/hematology-oncology/article/202868/bleeding-disorders/need-vwf-concentrate-therapy-appears-low?channel=27970
Caleb Rans

Jun 13th, 2019 - Only a limited number of patients with von Willebrand disease (VWD) are likely to require treatment with von Willebrand factor (VWF) concentrates, according to results from a retrospective analysis. The retrospective, single-center study sought to.

Liver resection appears safe in patients with hemophilia, VWD
https://www.mdedge.com/hematology-oncology/article/202863/bleeding-disorders/liver-resection-appears-safe-patients?channel=27970
Caleb Rans

Jun 13th, 2019 - Undergoing hepatectomy for the treatment of hepatocellular carcinoma in patients with von Willebrand disease or hemophilia A was found to be safe through the use of appropriate von Willebrand factor concentrate or recombinant factor VIII therapy,.

Study identifies GI bleed risk factors in von Willebrand disease
https://www.mdedge.com/hematology-oncology/article/200520/bleeding-disorders/study-identifies-gi-bleed-risk-factors-von?channel=27970
Caleb Rans

May 8th, 2019 - Researchers have identified several risk factors associated with gastrointestinal (GI) bleeding in adult patients with von Willebrand disease (VWD), based on findings from a retrospective analysis. “[We] evaluated prevalence and risk factors of GI.

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Patient Education  7 results see all →