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About 665 results

ALLMedicine™ Acquired Hemophilia Center

Research & Reviews  217 results

Anti-CD38 antibody for refractory acquired hemophilia A.
https://doi.org/10.1016/j.jtha.2023.03.010
Journal of Thrombosis and Haemostasis : JTH; Liu W, Liu J et. al.

Mar 21st, 2023 - Patients with acquired hemophilia A (AHA) are prone to bleeding symptoms due to decrease of factor VIII (FVIII) activity caused by FVIII antibodies. Risk of severe bleeding in AHA is higher than that of hereditary hemophilia, so clearance of FVIII...

Acquired Hemophilia
http://emedicine.medscape.com/article/211186-overview

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII). [1] Acq...

Acquired Hemophilia
https://emedicine.medscape.com/article/211186-print

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII).[1] Acqu...

Acquired Hemophilia
https://emedicine.medscape.com/article/211186-overview

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII). [1] Acq...

Above the threshold time of coagulation: delayed diagnosis of acquired hemophilia A.
https://doi.org/10.1016/j.amjmed.2023.01.044
The American Journal of Medicine; Kikuchi M, Harada Y et. al.

Feb 26th, 2023 - Above the threshold time of coagulation: delayed diagnosis of acquired hemophilia A.|2023|Kikuchi M,Harada Y,Hamai A,Takaoka S,|

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Guidelines  1 results

International recommendations on the diagnosis and treatment of patients with acquired ...
https://doi.org/10.3324/haematol.2008.001743
Haematologica Huth-Kühne A, Baudo F et. al.

Apr 2nd, 2009 - Acquired hemophilia A (AHA) is a rare bleeding disorder characterized by autoantibodies directed against circulating coagulation factor (F) VIII. Typically, patients with no prior history of a bleeding disorder present with spontaneous bleeding an...

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Drugs  10 results see all →

Clinicaltrials.gov  11 results

Trial of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab
https://clinicaltrials.gov/ct2/show/NCT03384277

Feb 17th, 2023 - This is a prospective randomized multi-center controlled pilot trial comparing the regimen of steroid with rituximab and steroid with cyclophosphamide to eradicate anti-factor VIII antibodies in Chinese patients with acquired hemophilia A. Patient...

Emicizumab in Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT04188639

Jan 9th, 2023 - This study is an international, multicenter, open-label, single arm, prospective clinical trial and will evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquired hemophilia A (A...

Study of TAK-672 in Participants With Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT04580407

Dec 29th, 2022 - The main aims of the study are to learn if TAK-672 can control bleeds in participants with acquired hemophilia A and if the participants have side effects from TAK-672. Acquired hemophilia A is when people's immune system attacks specific proteins...

Emicizumab in Patients With Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT05345197

Sep 10th, 2022 - Patients with AHA who are eligible will receive two loading doses of the study drug, emicizumab (6mg/kg on day 1 and 3 mg/kg on day 2) followed by once weekly subcutaneous emicizumab (1.5 mg/kg). Immunosuppression will be given concurrently as per...

Acquired Hemophilia A and Autoimmunity. Study of Lymphocyte Populations and Myeloid-Derived Suppressor Cells
https://clinicaltrials.gov/ct2/show/NCT04805021

Jan 11th, 2022 - Acquired hemophilia A is a rare condition of hemostasis secondary to the development of antibodies against factor VIII. This is a potentially serious pathology that can be life-threatening due to the major risk of bleeding caused by the sometimes ...

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News  25 results

Rituximab for Acquired Hemophilia A in the Setting of Bullous Pemphigoid
https://www.mdedge.com/dermatology/article/256573/mixed-topics/rituximab-acquired-hemophilia-setting-bullous-pemphigoid
Maria C. Bell, MD, Daniel C. Grove, MD et. al.

Jul 28th, 2022 - To the Editor: Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by the formation of antihemidesmosomal antibodies, resulting in tense bullae concentrated on the extremities and trunk that often are preceded by a pruritic u.

‘Time Is Blood’: Researchers Devise Shortcut to AHA Diagnosis
https://www.medscape.com/viewarticle/972442

Apr 20th, 2022 - Because they have detected sluggishness in hospital diagnoses, researchers have developed an algorithm to help clinicians determine whether patients have acquired hemophilia A (AHA), a rare bleeding disorder that mainly affects elderly men with me...

‘Time is blood’: Researchers devise shortcut to AHA diagnosis
https://www.mdedge.com/hematology-oncology/article/253869/bleeding-disorders/time-blood-researchers-devise-shortcut-aha
Randy Dotinga

Apr 18th, 2022 - Because they have detected sluggishness in hospital diagnoses, researchers have developed an algorithm to help clinicians determine whether patients have acquired hemophilia A (AHA), a rare bleeding disorder that mainly affects elderly men with me.

Post–COVID Vaccine AHA Cases Raise Eyebrows in Italy
https://www.medscape.com/viewarticle/968826

Feb 18th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Four cases of acquired hemophilia A (AHA) identified after SARS-CoV-2 immunizations in a province in northern Italy caught the attention of resear...

Post–COVID vaccine AHA cases raise eyebrows in Italy
https://www.mdedge.com/hematology-oncology/article/251919/bleeding-disorders/post-covid-vaccine-aha-cases-raise-eyebrows
Sharon Worcester

Feb 17th, 2022 - Four cases of acquired hemophilia A (AHA) identified after SARS-CoV-2 immunizations in a province in northern Italy caught the attention of researchers, who stressed that the cases are “unusual,” but not necessarily caused by vaccination. “The ove.

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Patient Education  2 results see all →