×
About 593 results

ALLMedicine™ Acquired Hemophilia Center

Research & Reviews  192 results

Rituximab for Acquired Hemophilia A in the Setting of Bullous Pemphigoid
https://www.mdedge.com/dermatology/article/256573/mixed-topics/rituximab-acquired-hemophilia-setting-bullous-pemphigoid
Maria C. Bell, MD, Daniel C. Grove, MD et. al.

Jul 28th, 2022 - To the Editor: Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by the formation of antihemidesmosomal antibodies, resulting in tense bullae concentrated on the extremities and trunk that often are preceded by a pruritic u.

Challenging treatment for refractory acquired haemophilia A complicated with severe sev...
https://doi.org/10.1097/MBC.0000000000001149
Blood Coagulation & Fibrinolysis : an International Journ... Cives TL, Docampo MF et. al.

Jul 15th, 2022 - Immunosuppressive treatment and bypassing agents are used to treat acquired haemophilia A (AHA). On the other hand, COVID-19 infection induces a hypercoagulable state. Managing bleeding, risk of thrombosis, bypassing agents, active infection and i...

Immune Complications and their Management in Inherited and Acquired Bleeding Disorders.
https://doi.org/10.1182/blood.2022016530
Blood Arruda VR, Lillicrap D et. al.

Jul 7th, 2022 - Disorders of coagulation, resulting in serious risks for bleeding, may be caused by autoantibody formation or by mutations in genes encoding coagulation factors. In the latter case, anti-drug antibodies may form against the clotting factor protein...

Emicizumab in Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT04188639

Jun 29th, 2022 - This study is an international, multicenter, open-label, single arm, prospective clinical trial and will evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquired hemophilia A (A...

Naturally Occurring Anti-Idiotypic Antibodies Portray a Largely Private Repertoire in I...
https://doi.org/10.4049/jimmunol.2100868
Journal of Immunology (Baltimore, Md. : 1950); Heeb SR, Schaller M et. al.

May 20th, 2022 - Rare immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a life-threatening disease resulting from a severe autoantibody-mediated ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motifs, member 13) deficiency. Acute...

see more →

Guidelines  1 results

International recommendations on the diagnosis and treatment of patients with acquired ...
https://doi.org/10.3324/haematol.2008.001743
Haematologica Huth-Kühne A, Baudo F et. al.

Apr 2nd, 2009 - Acquired hemophilia A (AHA) is a rare bleeding disorder characterized by autoantibodies directed against circulating coagulation factor (F) VIII. Typically, patients with no prior history of a bleeding disorder present with spontaneous bleeding an...

see more →

Drugs  6 results see all →

Clinicaltrials.gov  11 results

Emicizumab in Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT04188639

Jun 29th, 2022 - This study is an international, multicenter, open-label, single arm, prospective clinical trial and will evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquired hemophilia A (A...

Emicizumab in Patients With Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT05345197

Apr 25th, 2022 - Patients with AHA who are eligible will receive two loading doses of the study drug, emicizumab (6mg/kg on day 1 and 3 mg/kg on day 2) followed by once weekly subcutaneous emicizumab (1.5 mg/kg). Immunosuppression will be given concurrently as per...

Study of TAK-672 in Participants With Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT04580407

Jan 14th, 2022 - Efficacy and Safety Evaluation of B-Domain Deleted Recombinant Porcine Factor VIII (rpFVIII, TAK-672), in Japanese Participants with AHA

Acquired Hemophilia A and Autoimmunity. Study of Lymphocyte Populations and Myeloid-Derived Suppressor Cells
https://clinicaltrials.gov/ct2/show/NCT04805021

Jan 11th, 2022 - Acquired hemophilia A is a rare condition of hemostasis secondary to the development of antibodies against factor VIII. This is a potentially serious pathology that can be life-threatening due to the major risk of bleeding caused by the sometimes ...

Post-Marketing Non-Interventional Safety Evaluation of Obizur in the Treatment of Bleeding Episodes for Patients With Acquired Hemophilia A
https://clinicaltrials.gov/ct2/show/NCT02610127

Aug 5th, 2021 - This study is a multi-center, uncontrolled, open-label, non-interventional post-marketing safety surveillance study to describe the use of Obizur in patients with acquired hemophilia A (AHA), and secondarily, where data are available, to describe ...

see more →

News  25 results

Rituximab for Acquired Hemophilia A in the Setting of Bullous Pemphigoid
https://www.mdedge.com/dermatology/article/256573/mixed-topics/rituximab-acquired-hemophilia-setting-bullous-pemphigoid
Maria C. Bell, MD, Daniel C. Grove, MD et. al.

Jul 28th, 2022 - To the Editor: Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by the formation of antihemidesmosomal antibodies, resulting in tense bullae concentrated on the extremities and trunk that often are preceded by a pruritic u.

‘Time Is Blood’: Researchers Devise Shortcut to AHA Diagnosis
https://www.medscape.com/viewarticle/972442

Apr 20th, 2022 - Because they have detected sluggishness in hospital diagnoses, researchers have developed an algorithm to help clinicians determine whether patients have acquired hemophilia A (AHA), a rare bleeding disorder that mainly affects elderly men with me...

‘Time is blood’: Researchers devise shortcut to AHA diagnosis
https://www.mdedge.com/hematology-oncology/article/253869/bleeding-disorders/time-blood-researchers-devise-shortcut-aha
Randy Dotinga

Apr 18th, 2022 - Because they have detected sluggishness in hospital diagnoses, researchers have developed an algorithm to help clinicians determine whether patients have acquired hemophilia A (AHA), a rare bleeding disorder that mainly affects elderly men with me.

Post–COVID Vaccine AHA Cases Raise Eyebrows in Italy
https://www.medscape.com/viewarticle/968826

Feb 18th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Four cases of acquired hemophilia A (AHA) identified after SARS-CoV-2 immunizations in a province in northern Italy caught the attention of resear...

Post–COVID vaccine AHA cases raise eyebrows in Italy
https://www.mdedge.com/hematology-oncology/article/251919/bleeding-disorders/post-covid-vaccine-aha-cases-raise-eyebrows
Sharon Worcester

Feb 17th, 2022 - Four cases of acquired hemophilia A (AHA) identified after SARS-CoV-2 immunizations in a province in northern Italy caught the attention of researchers, who stressed that the cases are “unusual,” but not necessarily caused by vaccination. “The ove.

see more →

Patient Education  2 results see all →