About 263 results

ALLMedicine™ Antithrombin Deficiency Center

Research & Reviews  100 results

High penetrance of inferior vena cava system atresia in severe thrombophilia caused by ...
American Journal of Hematology; de la Morena-Barrio ME, Gindele R et. al.

Jul 30th, 2021 - Atresia of inferior vena cava (IVC) is a rare congenital malformation associated with high risk of venous thrombosis that still has unknown etiology, although intrauterine IVC thrombosis has been suggested to be involved. The identification of IVC...

Acquired antithrombin deficiency is a risk factor for venous thromboembolism after majo...
Thrombosis Research; Rahbar E, Cotton BA et. al.

Jun 7th, 2021 - Phospholipid monolayers formed at oil-water interfaces have been used to explore biological interface properties. Thus, monolayer systems need to be quantitatively understood. Previously, we investigated the formation of 1-palmitoyl-2-oleoyl-sn-gl...

Antithrombin deficiency: A pediatric disorder.
Thrombosis Research; Smith N, Warren BB et. al.

Mar 17th, 2021 - Hereditary antithrombin (AT) deficiency is an autosomal dominant thrombophilic disorder. Guidelines do not support routine testing of children based on personal or familial thrombosis. To investigate clinical, genetic and laboratory profiles of AT...

Antithrombin Dose Optimization in Extracorporeal Membrane Oxygenation in Infants.
ASAIO Journal (American Society for Artificial Internal O... Liviskie CJ, Lahart MA et. al.

Feb 3rd, 2021 - Anticoagulation in extracorporeal membrane oxygenation (ECMO) is challenging, with significant morbidity and mortality associated with thrombotic complications. Unfractionated heparin (UFH) is commonly used, which depends on native antithrombin (A...

Type II antithrombin deficiency caused by a novel missense mutation (p.Leu417Gln) in a ...
Blood Coagulation & Fibrinolysis : an International Journ... Liu S, Wang H et. al.

Nov 17th, 2020 - o explore the phenotype and genotype of a hereditary antithrombin deficient Chinese family. Functional and molecular analysis of the proband and his family members was performed. Online bioinformatics software was used to predict the pathogenicity...

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Drugs  1 results see all →

News  4 results

VTE Prophylaxis Warranted in Pregnant Women With Rare Thrombophilias

Nov 9th, 2017 - NEW YORK (Reuters Health) - Women with some rare forms of thrombophilia can benefit from ante- or postpartum thrombosis prophylaxis, but those with more common types generally do not need preventive treatment, according to a new meta-analysis. Pre...

Purpuric lesion on the elbow
Naveen K. Voore, MD, Asima Rahman, MD, MRCGP, MRCOG et. al.

Apr 1st, 2012 - A 75-year-old man was admitted to the hospital with new-onset atrial fibrillation. He underwent rate control, and a heparin infusion was started.

New FDA Orphan Drugs: CDX-110, ATryn, ISIS 333611

Dec 21st, 2007 - December 21, 2007 -- The US Food and Drug Administration (FDA) has granted orphan drug designation to CDX-110 for the treatment of glioblastoma multiforme, ATryn for the treatment of hereditary antithrombin deficiency, and ISIS 333611 for the trea...

Q.Are oral contraceptives safe for women with a thrombophilic defect?
Gerson Weiss, MD

Fast Track Women with a thrombophilic deficiency who used OCs developed VTE at a younger age than their non–OC-using counterparts A. No.

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