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About 303 results

ALLMedicine™ Antithrombin Deficiency Center

Research & Reviews  113 results

Management of heparin resistance due to antithrombin deficiency in a Chinese pregnant w...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647273
The Journal of International Medical Research; Zhang X, Guo F et. al.

Dec 2nd, 2021 - Untreated individuals with antithrombin (AT) deficiency are at higher risk of thrombosis and adverse pregnancy outcomes. The present recommendations are mostly empirical for treating patients with AT deficiency during pregnancy because of the abse...

Molecular and clinical characterization of transient antithrombin deficiency: A new con...
https://doi.org/10.1002/ajh.26413
American Journal of Hematology; Bravo-Pérez C, de la Morena-Barrio ME et. al.

Nov 21st, 2021 - Antithrombin deficiency, the most severe thrombophilia, might be underestimated, since it is only investigated in cases with consistent functional deficiency or family history. We have analyzed 444 consecutive, unrelated cases, from 1998 to 2021, ...

Unraveling a borderline antithrombin deficiency case with quantitative mass spectrometry.
https://doi.org/10.1111/jth.15553
Journal of Thrombosis and Haemostasis : JTH; Kruijt M, van der Pol LM et. al.

Oct 16th, 2021 - Antithrombin deficiency diagnostics by first-line activity tests suffer from a lack of sensitivity sometimes resulting in diagnostic uncertainty. We here present a case of a woman with recurrent pregnancy loss who was screened for inherited thromb...

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
https://clinicaltrials.gov/ct2/show/NCT04918173

Sep 20th, 2021 - Assess the incidence of the composite of thrombotic events (TEs) and thromboembolic events (TEEs) in patients with congenital antithrombin deficiency under cover of Atenativ for surgical procedures or parturition.

High penetrance of inferior vena cava system atresia in severe thrombophilia caused by ...
https://doi.org/10.1002/ajh.26304
American Journal of Hematology; de la Morena-Barrio ME, Gindele R et. al.

Jul 30th, 2021 - Atresia of inferior vena cava (IVC) is a rare congenital malformation associated with high risk of venous thrombosis that still has unknown etiology, although intrauterine IVC thrombosis has been suggested to be involved. The identification of IVC...

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Drugs  1 results see all →

Clinicaltrials.gov  2 results

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
https://clinicaltrials.gov/ct2/show/NCT04918173

Sep 20th, 2021 - Assess the incidence of the composite of thrombotic events (TEs) and thromboembolic events (TEEs) in patients with congenital antithrombin deficiency under cover of Atenativ for surgical procedures or parturition.

A Study of KW-3357 in Congenital Antithrombin Deficiency
https://clinicaltrials.gov/ct2/show/NCT00938288

Jun 17th, 2011 - Patients with Congenital Antithrombin Deficiency are at increased risk of venous thrombosis and pulmonary embolism especially when undergoing certain high risk procedures. Antithrombin replacement therapy is often administered during these periods...

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News  5 results

VTE Prophylaxis Warranted in Pregnant Women With Rare Thrombophilias
https://www.medscape.com/viewarticle/888208

Nov 9th, 2017 - NEW YORK (Reuters Health) - Women with some rare forms of thrombophilia can benefit from ante- or postpartum thrombosis prophylaxis, but those with more common types generally do not need preventive treatment, according to a new meta-analysis. Pre...

Pregnancy-Linked VTE Risk Varies by Type of Thrombophilia
https://www.medpagetoday.com/obgyn/pregnancy/68853

Oct 27th, 2017 - Absolute risk of pregnancy-associated venous thromboembolism (VTE) varied depending on the type of thrombophilia among women with a family history of VTE, a systematic review and meta-analysis found. While all thrombophilias increased the risk of ...

Purpuric lesion on the elbow
https://www.mdedge.com/ccjm/article/95725/dermatology/purpuric-lesion-elbow?channel=194
Naveen K. Voore, MD, Asima Rahman, MD, MRCGP, MRCOG et. al.

Apr 1st, 2012 - A 75-year-old man was admitted to the hospital with new-onset atrial fibrillation. He underwent rate control, and a heparin infusion was started.

New FDA Orphan Drugs: CDX-110, ATryn, ISIS 333611
https://www.medscape.com/viewarticle/567860

Dec 21st, 2007 - December 21, 2007 -- The US Food and Drug Administration (FDA) has granted orphan drug designation to CDX-110 for the treatment of glioblastoma multiforme, ATryn for the treatment of hereditary antithrombin deficiency, and ISIS 333611 for the trea...

Q.Are oral contraceptives safe for women with a thrombophilic defect?
https://www.mdedge.com/obgyn/article/62659/qare-oral-contraceptives-safe-women-thrombophilic-defect
Gerson Weiss, MD

Fast Track Women with a thrombophilic deficiency who used OCs developed VTE at a younger age than their non–OC-using counterparts A. No.

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