ALLMedicine™ Antithrombin Deficiency Center
Research & Reviews 158 results
https://doi.org/10.1038/d41573-023-00008-w
Nature Reviews. Drug Discovery; Crunkhorn S
Jan 12th, 2023 - Gene editing addresses antithrombin deficiency.|2023|Crunkhorn S,|
https://doi.org/10.1007/s12185-022-03509-3
International Journal of Hematology; Imai Y, Nagaya S et. al.
Dec 17th, 2022 - Hereditary antithrombin (AT) deficiency is an autosomal dominant inherited thrombophilia. In three pedigrees of hereditary type I AT deficiency, we identified novel variants c.126delC (p.Lys43Serfs*7), c.165C > G (p.Tyr55*), and c.546delA (p.Lys18...
https://doi.org/10.1097/MBC.0000000000001183
Blood Coagulation & Fibrinolysis : an International Journ... Stevens-Haas CL, Livergood MC et. al.
Nov 29th, 2022 - Literature regarding the management of thrombus refractory to first-line treatment in the setting of pregnancy is limited, and management is made even more complicated in the context of thrombophilia. This case reviews the management of a patient ...
https://clinicaltrials.gov/ct2/show/NCT04925167
Nov 9th, 2022 - Unfractionated heparin is most common in the anticoagulation management of V-V ECMO. However, many side effects of unfractionated heparin, such as HIT, antithrombin deficiency, etc seriously affects the prognosis of patients. Argatroban is kind of...
https://doi.org/10.1097/MD.0000000000031240
Medicine Hou X, Zhang K et. al.
Nov 8th, 2022 - Inherited antithrombin deficiency (ATD) is a major cause of thrombotic deficiency. Genetic testing is of great value in the diagnosis of hereditary thrombophilia. Herein, we report a case of inherited ATD admitted to our hospital. We include the r...
Drugs 1 results see all →
Clinicaltrials.gov 8 results
https://clinicaltrials.gov/ct2/show/NCT04925167
Nov 9th, 2022 - Unfractionated heparin is most common in the anticoagulation management of V-V ECMO. However, many side effects of unfractionated heparin, such as HIT, antithrombin deficiency, etc seriously affects the prognosis of patients. Argatroban is kind of...
https://clinicaltrials.gov/ct2/show/NCT04918173
Sep 19th, 2022 - Assess the incidence of the composite of thrombotic events (TEs) and thromboembolic events (TEEs) in patients with congenital antithrombin deficiency under cover of Atenativ for surgical procedures or parturition.
https://clinicaltrials.gov/ct2/show/NCT00319228
May 11th, 2022 - This study will be a prospective, unblinded, non-randomized, open-label, multi-center Phase II/III study with 2 segments, i.e. a PK evaluation (Segment I), and an assessment of prophylaxis in surgical interventions and pregnancy/delivery, (Segment...
https://clinicaltrials.gov/ct2/show/NCT04133844
Jun 4th, 2021 - Our hypothesis is that ECMO initiation is responsible for a severe decrease of antithrombin level in a high proportion of patients who develop heparin resistance.
https://clinicaltrials.gov/ct2/show/NCT02503267
Mar 27th, 2017 - Congenital disorders of glycosylation (CDG) are a family of inherited disorders caused by defects in the synthesis of glycans, glycoproteins or other glycoconjugates. Congenital disorders of glycosylation (CDG) are a family of inherited disorders ...
News 6 results
https://www.medpagetoday.com/cardiology/prevention/99483
Jun 28th, 2022 - The American College of Cardiology and American Heart Association released unified data standards for reporting of cardiovascular conditions related to COVID-19. (Circulation: Cardiovascular Quality and Outcomes) Environmental predictors of cardio...
https://www.medscape.com/viewarticle/888208
Nov 9th, 2017 - NEW YORK (Reuters Health) - Women with some rare forms of thrombophilia can benefit from ante- or postpartum thrombosis prophylaxis, but those with more common types generally do not need preventive treatment, according to a new meta-analysis. Pre...
https://www.medpagetoday.com/obgyn/pregnancy/68853
Oct 27th, 2017 - Absolute risk of pregnancy-associated venous thromboembolism (VTE) varied depending on the type of thrombophilia among women with a family history of VTE, a systematic review and meta-analysis found. While all thrombophilias increased the risk of ...
https://www.mdedge.com/ccjm/article/95725/dermatology/purpuric-lesion-elbow?channel=194
Naveen K. Voore, MD, Asima Rahman, MD, MRCGP, MRCOG et. al.
Apr 1st, 2012 - A 75-year-old man was admitted to the hospital with new-onset atrial fibrillation. He underwent rate control, and a heparin infusion was started.
https://www.medscape.com/viewarticle/567860
Dec 21st, 2007 - December 21, 2007 -- The US Food and Drug Administration (FDA) has granted orphan drug designation to CDX-110 for the treatment of glioblastoma multiforme, ATryn for the treatment of hereditary antithrombin deficiency, and ISIS 333611 for the trea...