ALLMedicine™ Factor II Center

Jun 29th, 2022 - Background Vitamin D is a fat-soluble vitamin, and it is a potential key factor to maintain a healthy status. Various observational studies have reported the association between vitamin D deficiency and an elevated risk of osteoporosis, cardiovasc...

Jun 28th, 2022 - TAF8 is part of the transcription factor II D complex, composed of the TATA-binding protein and 13 TATA-binding protein-associated factors (TAFs). Transcription factor II D is the first general transcription factor recruited at promoters to assemb...

Jun 25th, 2022 - There is increasing interest in leukoreduced whole blood (WB) as a transfusion product for trauma patients. In some jurisdictions, few leukoreduced filters are approved or appropriate for WB leukoreduction and quality information is therefore limi...

Jun 13th, 2022 - The investigators will study the effect of vitamin K supplementation on two biomarkers of hepatic vitamin K concentration in groups with defined CYP4F2*3 genotype. Specifically, the investigators will test for an association between our novel biom...

Jun 10th, 2022 - Some patients suffering from the new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) develop an exaggerated inflammatory response triggered by a "cytokine storm" resulting in acute respiratory distress syndrome (ARDS) with the concomi...

Jun 13th, 2022 - The investigators will study the effect of vitamin K supplementation on two biomarkers of hepatic vitamin K concentration in groups with defined CYP4F2*3 genotype. Specifically, the investigators will test for an association between our novel biom...

Apr 1st, 2022 - Laryngeal cancer is responsible for 2-5% of all new cancer cases worldwide. Squamous cell carcinoma of the larynx (LSCC) is the most common malignant tumor of the larynx, accounting for 85-90% of all laryngeal malignancies. Despite significant the...

Feb 15th, 2022 - This study has conducted to find the possible links between genetic make up of ICU patients with severe Covid-19 and embolism. 13 polymorphisms and mutations that the investigators targeted are located on Factor II, Factor V, Factor XIII, MTHFR, a...

Jan 11th, 2022 - This study will be a randomized (1:1; PCC vs. plasma), open-label trial of hemostatic therapies during heart transplantation. The goal is to enroll 60 patients. Informed consent will be obtained from patients meeting the inclusion and exclusion cr...

Jan 11th, 2022 - Molecular biomarkers could selectively identify patients with a more unfavorable clinical course. One of these biomarkers is IMP3 - insulin-like growth factor II mRNA binding protein. The IGF group is a complex regulatory network at the cellular a...

Oct 4th, 2021 - Abstract Ovarian cancer is a relatively rare but deadly disease. Biomarker panels for the detection of ovarian cancer are usually combined with screening for CA125, a known marker of ovarian cancer, and transabdominal or transvaginal ultrasonogr...

Feb 3rd, 2020 - In December 2019, the European Stroke Organisation (ESO) released their recommendations on the reversal of oral anticoagulants in acute intracerebral hemorrhage (ICH).[1] Oral anticoagulants include vitamin K antagonists (VKAs) (warfarin, phenproc...

Jan 27th, 2019 - Patients with self-reported mild bleeding symptoms may have impaired clot lysis, according to investigators. This finding is remarkable because it contrasts with known bleeding disorders, such as hemophilia, which are associated with enhanced clot.

Apr 25th, 2018 - Elevated vascular biomarkers were associated with migraine, a recent study found, particularly migraine with aura (MA), as well as with years of aura and number of aura attacks. Participants (300 women, 117 men) were aged 30–60 (mean 48) years, 15.

May 1st, 2017 - INTRODUCTION Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a leading nonobstetric cause of maternal death in the United States and in developed countries. 1,2 During pregnancy, the risk for VTE.