ALLMedicine™ Factor IX Deficiency Center

Jan 5th, 2023 - Hemophilia is a rare inherited disease which causes bleeding due to Factor VIII or Factor IX deficiency. It is usually X-linked recessive and typically affects males. Arthropathy occurs as a result of cartilage damage and chronic synovitis due to ...

Dec 22nd, 2022 - Practice Essentials Hemophilia B, or Christmas disease, is an inherited, recessive disorder that involves deficiency of functional coagulation factor IX (FIX) in plasma. Hemophilia B is caused by a variety of defects in the F9 gene. [1] As this ge...

Dec 22nd, 2022 - Approach Considerations Laboratory studies for suspected hemophilia B include a complete blood cell count, coagulation studies, and a factor IX (FIX) assay. Never delay indicated coagulation correction pending diagnostic testing. The United Kingdo...

Dec 22nd, 2022 - History Hemophilia is suggested by a history of hemorrhage disproportionate to trauma or of spontaneous hemorrhage, or a family history of bleeding problems. Concomitant illness may include chronic inflammatory disorders, autoimmune diseases, hema...

Dec 22nd, 2022 - Approach Considerations The treatment of hemophilia may involve management of hemostasis, management of bleeding episodes, use of factor replacement products and medications, treatment of patients with factor inhibitors, and treatment and rehabili...

Jul 11th, 2022 - Hemophilia is defined as bleeding in the musculoskeletal system and soft tissues as a result of the lack of clotting factors in the blood. Recurrent attacks of hemarthrosis cause pain, also because of the pain patients tend to use joints less than...

Oct 17th, 2018 - Patients with hemophilia B (congenital blood coagulation factor IX deficiency) who are administered this drug. Patients with hemophilia B are either patients for whom treatment was already started with a blood coagulation factor IX product ("Previ...

Jun 24th, 2005 - PROTOCOL OUTLINE: Patients receive monoclonal factor IX replacement therapy as inpatients. Patients with a satisfactory response receive further therapy as needed for bleeding for up to 36 months at home.

Apr 10th, 2019 - The state of Indiana had higher hemophilia incidence and prevalence rates, compared with national estimates, according to results from a statewide epidemiologic analysis. “[The study] aimed to identify all persons with hemophilia, including those.

Apr 10th, 2019 - The state of Indiana had higher hemophilia incidence and prevalence rates, compared with national estimates, according to results from a statewide epidemiologic analysis. “[The study] aimed to identify all persons with hemophilia, including those.

Dec 1st, 2018 - Over one-third of adolescents presenting with heavy menstrual bleeding were diagnosed with a bleeding disorder after screening, according to results of a retrospective study. ©Catherine Yeulet/thinkstockphotos.

Mar 24th, 2017 - The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommend nonacog beta pegol (Refixia, Novo Nordisk A/S) for the treatment and prophylaxis of bleeding in patients aged 12 years and older with hemophili...

Mar 5th, 2015 - Lentiviral vectors effectively deliver the gene that encodes coagulation factor IX (FIX) to the liver in dogs with naturally occurring hemophilia B (factor IX deficiency), researchers report in an article published in the March 4 issue of Science ...