About 2,300 results

ALLMedicine™ Factor VII Center

Research & Reviews  775 results

Structural and functional characterization of novel F7 mutations identified in Chinese ...
British Journal of Haematology; Lou C, Jiang J et. al.

Mar 24th, 2023 - Hereditary factor VII (FVII) deficiency is a rare recessive bleeding disorder with an estimated prevalence of 1/500 000. We had investigated 50 unrelated Chinese patients with FVII deficiency and identified, in total, 25 mutations, including 18 mi...

Acquired Hemophilia

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII). [1] Acq...

Acquired Hemophilia

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII).[1] Acqu...

Acquired Hemophilia

Mar 17th, 2023 - Practice Essentials Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII). [1] Acq...

Comparison of Prothrombin Complex Concentrate with Activated Factor VII Use for Bleedin...
World Journal for Pediatric & Congenital Heart Surgery; Benson JW, Hraska V et. al.

Mar 16th, 2023 - This study aims to compare the efficacy and safety of activated recombinant factor VII (rFVIIa) and prothrombin complex concentrate (PCC) in the treatment of bleeding complications following surgery requiring cardiopulmonary bypass (CPB) in childr...

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Guidelines  2 results

Damage control resuscitation in patients with severe traumatic hemorrhage: A practice m...
The Journal of Trauma and Acute Care Surgery; Cannon JW, Khan MA et. al.

Feb 23rd, 2017 - The resuscitation of severely injured bleeding patients has evolved into a multi-modal strategy termed damage control resuscitation (DCR). This guideline evaluates several aspects of DCR including the role of massive transfusion (MT) protocols, th...

Active management of the third stage of labour: prevention and treatment of postpartum ...
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Leduc D, Senikas V et. al.

Nov 28th, 2009 - To review the clinical aspects of postpartum hemorrhage (PPH) and provide guidelines to assist clinicians in the prevention and management of PPH. These guidelines are an update from the previous Society of Obstetricians and Gynaecologists of Cana...

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Drugs  5 results see all →

Clinicaltrials.gov  92 results

A Survey on the Success of Inhibitor Elimination Using Individualized Concentrate Selection and Controlled ITI

Mar 3rd, 2023 - As a result of many technological advances in the last two decades, current factor VIII (FVIII) concentrates (both plasma-derived and recombinant products) are considered very safe in terms of pathogen safety. The development of inhibitors against...

Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy

Feb 21st, 2023 - Dacryocystorhinostomy aims to create a channel between the lacrimal sac and nasal mucosa to relieve nasolacrimal duct occlusion. General anesthesia is still preferred by many surgeons to secure the airway and control blood pressure. Bleeding even ...

Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery

Jan 10th, 2023 - Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions. In addition, some of these patients ...

SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis

Jan 6th, 2023 - The previous standard of care for high titer antibody eradication in hemophilia A (HA) included a labor-intensive, immune tolerance induction (ITI) regimen administered with concomitant bypassing agent (BPA) prophylaxis, either daily recombinant a...

Influence of Cardiac Implantable Electronic Devices on the Hemostatic System

Oct 27th, 2022 - 250 patients of similar age, gender, and ethnicity will be divided into five groups: Group A1-3: 150 patients with indications for cardiac implantable electronic device (CIED) implantation; Group B: 50 patients with an CIED implanted 8-10 years ag...

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News  46 results

Venous Thromboembolism and Cancer: An Opportunity for Pharmacists to Optimize Care

Dec 5th, 2020 - The management of venous thromboembolism (VTE) disorders is well described in the literature,1 and comprehensive guidelines are available from the American College of Chest Physicians.2 In addition, guidelines are available that specifically addre...

Pharmacyclics Hopes to Break Through With Blood Cancer Drug Ibrutinib

Jun 30th, 2020 - Sunnyvale, California-based Pharmacyclics has yet to lay claim to any FDA-approved therapeutics since it was formally incorporated in 1991, but that may very well change in the near future as a first-in-class drug for certain B-cell malignancies i...

FDA approves recombinant treatment for hemophilia A or B with inhibitors
Christopher Palmer

Apr 2nd, 2020 - The Food and Drug Administration has approved a new rabbit-derived recombinant analog of human coagulation factor VII (Sevenfact) for the treatment of hemophilia A or B, according to a release from the agency. The treatment’s approval is for use i.

Bleeding disorders don’t carry increased risks for patients undergoing endoscopy
Andrew D. Bowser

Mar 13th, 2019 - When managed by an experienced team, patients with inherited bleeding disorders undergoing gastrointestinal endoscopy are not at increased bleeding risk, according to researchers reporting the largest series of such patients to date. The postendos.

Can Magnesium Stop Bleeding in ICH, Improve Outcomes?

Aug 25th, 2017 - Lower levels of magnesium on hospital admission for intracerebral hemorrhage (ICH) are associated with larger hematoma volumes and growth, as well as worse functional outcomes at 3 months, suggesting an important role of magnesium in coagulation a...

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