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ALLMedicine™ Factor XI Deficiency Center

Research & Reviews  91 results

Factor XI Deficiency
https://emedicine.medscape.com/article/209984-overview

Jun 15th, 2022 - Practice Essentials Factor XI (FXI) deficiency is a rare autosomal disorder that may be associated with bleeding. [1] (See the image below.) Factor XI deficiency. Diagram from the traditional cascade-waterfall model of coagulation shows the place ...

Factor XI Deficiency
https://emedicine.medscape.com/article/209984-print

Jun 15th, 2022 - Practice Essentials Factor XI (FXI) deficiency is a rare autosomal disorder that may be associated with bleeding.[1] (See the image below.) Factor XI deficiency. Diagram from the traditional cascade-waterfall model of coagulation shows the place o...

Factor XI Deficiency
http://emedicine.medscape.com/article/209984-overview

Jun 15th, 2022 - Practice Essentials Factor XI (FXI) deficiency is a rare autosomal disorder that may be associated with bleeding. [1] (See the image below.) Factor XI deficiency. Diagram from the traditional cascade-waterfall model of coagulation shows the place ...

Abnormal (Dysfunctional) Uterine Bleeding Workup
http://emedicine.medscape.com/article/257007-workup

Mar 29th, 2022 - Laboratory Studies Laboratory studies for patients with abnormal uterine bleeding (AUB) may include human chorionic gonadotropin (HCG), complete blood count (CBC), Pap smear, endometrial sampling, thyroid functions and prolactin, liver functions, ...

Hemophilia C
https://emedicine.medscape.com/article/955690-overview

Mar 8th, 2022 - Practice Essentials Hemophilia C (deficiency of factor XI) was described first in two sisters and a maternal uncle of an American Jewish family. All three bled after dental extractions, and the sisters also bled after tonsillectomy. (See Etiology ...

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Clinicaltrials.gov  3 results

Cross-sectional Study on Prevalence of Coagulation Factors Deficiency in Assiut University Children Hospital
https://clinicaltrials.gov/ct2/show/NCT03273998

Sep 12th, 2017 - The most frequent inherited coagulation disorders are haemophilia A and B, due to the deficiency of factor VIII and IX. Haemophilia A and B are clinically indistinguishable from each other and occur in mild, moderate and severe forms (with plasma f...

HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
https://clinicaltrials.gov/ct2/show/NCT01701947

Aug 23rd, 2013 - Many patients are asymptomatic until hemostatically challenged by surgery or trauma; so, the diagnosis is often made in late childhood or early adulthood but always after full liver maturation (i.e. 6 months) as reported by Andrew et al. Spontaneo...

A Single and Low Dose of Recombinant Factor VIIa in Patients With Severe Factor XI Deficiency Undergoing Surgery
https://clinicaltrials.gov/ct2/show/NCT01538160

Feb 23rd, 2012 - Eligible patients will be those with severe factor XI deficiency who agree to participate in the study . The treatment does not apply to patients requiring coronary artery bypass or other vascular surgery.

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News  4 results

Bleeding disorders don’t carry increased risks for patients undergoing endoscopy
https://www.mdedge.com/hematology-oncology/article/196316/bleeding-disorders/bleeding-disorders-dont-carry-increased-risks
Andrew D. Bowser

Mar 13th, 2019 - When managed by an experienced team, patients with inherited bleeding disorders undergoing gastrointestinal endoscopy are not at increased bleeding risk, according to researchers reporting the largest series of such patients to date. The postendos.

FDA clears direct-to-consumer marketing of genetic risk tests
https://www.mdedge.com/hematology-oncology/article/185766/anemia/fda-clears-direct-consumer-marketing-genetic-risk-tests
HT Staff

Apr 7th, 2017 - Image by Spencer Phillips DNA helix The US Food and Drug Administration (FDA) has authorized marketing of 23andMe Personal Genome Service (PGS) Genetic Health Risk (GHR) tests for 10 medical conditions. These are the first direct-to-consumer tests.

FDA OKs First Direct-to-Consumer Genetic Risk Tests
https://www.medscape.com/viewarticle/878287

Apr 6th, 2017 - In the latest step toward personalized medicine, the US Food and Drug Administration (FDA) today approved the first direct-to-consumer (DTC) genetic tests that provide information on a person's risk of developing a disease. The tests in question, ...

Factor XI inhibitor trims DVTs after knee replacement surgery
https://www.mdedge.com/anticoagulationhub/article/97309/geriatrics/factor-xi-inhibitor-trims-dvts-after-knee-replacement
Patrice Wendling

Feb 20th, 2015 - SAN FRANCISCO – Reducing factor XI levels with the experimental antisense oligonucleotide FXI-ASO lowered venous thromboembolism rates after total knee arthroplasty without increasing bleeding in a phase II study. Venous thromboembolism (VTE) rate.

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