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About 418 results

ALLMedicine™ Hemolytic-uremic Syndrome Center

Research & Reviews  146 results

The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical he...
https://doi.org/10.1007/s00467-021-05372-6 10.1681/ASN.2004100861 10.1007/s00467-016-3399-0 10.1093/hmg/ddaa044 10.1016/j.ydbio.2020.09.005 10.1055/s-2000-8472 10.1007/s10545-007-0571-5 10.1038/ng1683 10.1172/JCI129937 10.1136/bcr-2015-211989 10.1007/s004310051190 10.1007/s00467-013-2443-6 10.3390/toxins11110660 10.1212/WNL.0000000000010912
Pediatric Nephrology (Berlin, Germany); Wood WD, Elmaghrabi A et. al.

Dec 3rd, 2021 - Cobalamin C (cblC), a vitamin B12 processing protein, plays a crucial role in metabolism for the conversion of homocysteine to methionine and methylmalonyl-CoA to succinyl-CoA. CblC deficiency, an inborn error of cobalamin processing, is a rare ca...

COVID-19 Associated Coagulopathy: Mechanisms and Host-Directed Treatment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576106
The American Journal of the Medical Sciences; Plášek J, Gumulec J et. al.

Nov 10th, 2021 - Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is associated with specific coagulopathy that frequently occurs during the different phases of coronavirus disease 2019 (COVID-19) and can result in thrombotic complications and/or death...

Belatacept 3 Month Post Transplant Conversion Study
https://clinicaltrials.gov/ct2/show/NCT02213068

Sep 8th, 2021 - Immunosuppressive therapy with the calcineurin inhibitors (CNI) cyclosporine (CsA) and Tacrolimus (Tac), have radically changed the field of organ transplantation. Ironically, although extensively and effectively used for kidney transplantation an...

Pediatric Nephritis Differential Diagnoses
https://emedicine.medscape.com/article/982811-differential

Aug 27th, 2021 - Diagnostic Considerations Conditions that produce hematuria, decreased clearance, and, sometimes, hypertension include all specific types of glomerulonephritis (GN), anatomic abnormalities of the kidneys, renal stones, tumors, drugs, and infection...

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Clinicaltrials.gov  4 results

Belatacept 3 Month Post Transplant Conversion Study
https://clinicaltrials.gov/ct2/show/NCT02213068

Sep 8th, 2021 - Immunosuppressive therapy with the calcineurin inhibitors (CNI) cyclosporine (CsA) and Tacrolimus (Tac), have radically changed the field of organ transplantation. Ironically, although extensively and effectively used for kidney transplantation an...

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry
https://clinicaltrials.gov/ct2/show/NCT01522183

May 18th, 2020 - The study will capture post-marketing safety data on patients treated with eculizumab or ravulizumab. Additionally, the study will collect information on the progression of disease in all patients.

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS
https://clinicaltrials.gov/ct2/show/NCT00844428

Jul 23rd, 2015 - The purpose of this study is to determine whether eculizumab is safe and effective in the treatment of adolescent patients with plasma therapy-sensitive Atypical Hemolytic-Uremic Syndrome (aHUS).

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)
https://clinicaltrials.gov/ct2/show/NCT00838513

Jul 23rd, 2015 - The purpose of this study is to determine whether eculizumab is safe and effective in the treatment of adult patients with plasma therapy-sensitive Atypical Hemolytic-Uremic Syndrome (aHUS).

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News  17 results

High Responses Observed With Avelumab Added to Regimen for Metastatic Colorectal Cancer Does Not Translate to PFS
https://www.onclive.com/view/high-responses-observed-with-avelumab-added-to-regimen-for-metastatic-colorectal-cancer-does-not-translate-to-pfs

Dec 20th, 2020 - Meinolf Karthaus, MD A regimen of avelumab (Bavencio) and cetuximab (Erbitux) plus oxaliplatin, leucovorin, and 5-fluorouracil (5-FU; mFOLFOX6) in patients with RAS/BRAF-wildtype metastatic colorectal cancer induced a very high response rate but ...

Talley Traces Developments in Chronic Leukemias
https://www.onclive.com/view/talley-traces-developments-in-chronic-leukemias

Dec 4th, 2020 - Robert L. Talley, MD Data presented at the 2018 ASCO Annual Meeting indicated both significant remission rates and improved side effect profiles with single agents and combinations in chronic leukemias, said Robert L. Talley, MD. The oncologic w...

Egypt prosecutor says e-coli was factor in deaths of British tourists
https://www.reuters.com/article/us-egypt-tourists/egypt-prosecutor-says-e-coli-was-factor-in-deaths-of-british-tourists-idUSKCN1LS2D8

Sep 12th, 2018 - CAIRO (Reuters) - Egypt’s public prosecutor said on Wednesday that e-coli bacteria were a factor in the deaths of two British tourists in the Red Sea resort of Hurghada last month. FILE PHOTO: A view of the Red Sea resort of Hurghada, Egypt, Augus...

E coli and Food Safety: It's a Jungle Out There
https://www.medscape.com/viewarticle/895308

Apr 23rd, 2018 - Foodborne illnesses are a substantial yet largely preventable health burden worldwide. We previously reviewed food safety in the United States[1] and harked back to the classic book, The Jungle, which portrayed the unsanitary conditions and practi...

E coli and Food Safety: It's a Jungle Out There
https://www.medscape.com/viewarticle/895308_1

Apr 23rd, 2018 - Foodborne illnesses are a substantial yet largely preventable health burden worldwide. We previously reviewed food safety in the United States[1] and harked back to the classic book, The Jungle, which portrayed the unsanitary conditions and practi...

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