ALLMedicine™ Protein S Deficiency Center

Jun 15th, 2022 - Idiopathic purpura fulminans (PF) is rare but has been reported in pediatric patients, commonly following infections. We present a case of a 5-year-old boy, heterozygous for factor V Leiden, with no history of recent infections, who presented with...

May 4th, 2022 - To describe the characteristics of patients with cerebral venous sinus thrombosis (CVST) and dural arteriovenous fistula (AVF) associated with protein S (PS) deficiency. We conducted a search of medical records in Hainan General Hospital from Janu...

Jan 21st, 2022 - The aim of this study was to analyse the risk factors of pregnancy loss of patients with recurrent spontaneous abortion (RSA) and develop a scoring system to predict RSA. Clinical data of 242 cases, with RSA who were treated at Fujian Provincial M...

Jan 16th, 2022 - Protein S deficiency is associated with an increased risk of thromboembolism, which may be caused by hereditary deficiency and several physiological and pathologic conditions, such as pregnancy, contraceptive use, liver diseases, inflammatory dise...

Dec 31st, 2021 - Venous thrombosis remains a significant problem in modern days. Genetic factors contribute to a subset of patients with venous thrombosis. It is sometimes challenging to identify the underlying culprit in thrombophilic individuals based on traditi...

Apr 21st, 2010 - Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed as a result of the wide spectrum of clinical symptoms and the often subacute or lingeri...

Apr 28th, 2021 - Thromboembolic events are among the leading causes of maternal morbidity and mortality in pregnancy / postpartum period. They are the leading cause of maternal death in developed countries. Risk factors for venous thromboembolism (VTE) during preg...

Jan 31st, 2017 - Subject Selection: The study population will include low risk patients on long-term warfarin therapy for venous thromboembolic disease (VTE) followed by the hematology anticoagulation clinic. Low risk will be defined as status greater than 12 mont...

Mar 5th, 2015 - Standard investigations fail to reveal any apparent cause in 50% of the cases of recurrent spontaneous abortion. Prothrombotic mechanisms were initially evoked. Factor V Leiden, Prothrombin G20210A mutation and protein S deficiency are implicated ...

Dec 16th, 2014 - If the thrombotic tendency plays a significant role in the etiology of psychosis, one would expect to find ischemic brain injuries in neuroimaging studies, but it does not happen. Therefore, if there is a correlation between thrombotic tendency-hy...

Dec 3rd, 2018 - Nephrotic syndrome is one of several disease states that increase a patient's risk of developing VTE. VTE associated with nephrotic syndrome appears to be due to a hypercoagulable state resulting from urinary loss of anticoagulant proteins, togeth...

Feb 22nd, 2018 - Tranexamic acid is a synthetic lysine derivative that inhibits plasminogen activation by blocking lysine-binding sites on the plasminogen molecule. Although the US Food and Drug Administration–approved indications for tranexamic acid include treat.

Nov 9th, 2017 - NEW YORK (Reuters Health) - Women with some rare forms of thrombophilia can benefit from ante- or postpartum thrombosis prophylaxis, but those with more common types generally do not need preventive treatment, according to a new meta-analysis. Pre...

May 3rd, 2016 - Fistula developed after delivery: $50M verdict During delivery of a 31-year-old woman's baby, a nuchal cord was encountered. In order to safely deliver the child, the ObGyn performed an episiotomy.

Apr 19th, 2015 - Deficiency of the endogenous anticoagulant proteins antithrombin, protein C, and protein S are significantly associated with an increased risk of a first episode of venous thromboembolism, according to a study published in Thrombosis Research. To.