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ALLMedicine™ Castleman Disease Center

Research & Reviews  372 results

Castleman disease.
https://doi.org/10.1038/s41572-021-00323-9
Nature Reviews. Disease Primers;

Nov 27th, 2021 - Castleman disease.|2021||

Castleman Disease
http://emedicine.medscape.com/article/2219018-overview

Nov 24th, 2021 - Practice Essentials Castleman disease (CD) describes a group of three immunologic disorders that occur in individuals of all ages and share a similar microscopic lymph node appearance, with signs and symptoms related to the release of cytokines, p...

Concomitant malignancies in the neck: follicular dendritic cell sarcoma; a rare tumour ...
https://doi.org/10.1136/bcr-2021-244175
BMJ Case Reports; Umakanth S, Lakshminarayana B et. al.

Nov 19th, 2021 - Follicular dendritic cell sarcoma is a rare low-grade sarcoma of mesenchymal origin. It involves the lymph nodes more commonly and rarely extranodal sites. The most common lymph node is cervical and usually presents as a painless asymptomatic mass...

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT02659930

Nov 17th, 2021 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor that most frequently involves skin, but can also involve lymph nodes, lungs and gastrointestinal tract. It is most common in people with HIV or other forms of immune compro...

Posttransplantation Lymphoproliferative Disorders
http://emedicine.medscape.com/article/854651-overview

Nov 15th, 2021 - Practice Essentials Lymphoproliferative disorders (LPDs) can be parsed into the following 6 categories: Hodgkin disease Non-Hodgkin lymphoma Histiocytosis X Benign reactive lymphoproliferative disorders (including posttransplantation lymphoprolife...

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Drugs  1 results see all →

Clinicaltrials.gov  7 results

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT02659930

Nov 17th, 2021 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor that most frequently involves skin, but can also involve lymph nodes, lungs and gastrointestinal tract. It is most common in people with HIV or other forms of immune compro...

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT05028621

Nov 3rd, 2021 - The study team will examine genetic changes, also known as mutations, in the DNA of participants' blood, or if applicable, bone marrow specimen. These types of tests are increasingly used by doctors to improve the accuracy of diagnosis and make de...

History of the KSHV Inflammatory Cytokine Syndrome (KICS)
https://clinicaltrials.gov/ct2/show/NCT01419561

Oct 4th, 2021 - BACKGROUND: KSHV inflammatory cytokine syndrome (KICS) is a newly recognized syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV). It is characterized by severe inflammatory symptoms including fevers, wasting, cytopenias, hypoalbuminemi...

International Registry for Patients With Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT02817997

Aug 24th, 2021 - This project is supported by the Castleman Disease Collaborative Network. Visit the CDCN website at http://www.cdcn.org/accelerate to sign up for the ACCELERATE registry! The ACCELERATE patient registry will give patients and families the opportun...

Safety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi
https://clinicaltrials.gov/ct2/show/NCT04585893

Aug 16th, 2021 - This study aims to determine the safety and efficacy of first-line, risk-stratified rituximab-based MCD treatment in Malawi in a single-arm, phase II clinical trial. The investigators will enroll 27 subjects with newly diagnosed or previously trea...

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News  10 results

Teaching an Old Dog New Tricks: Repurposing Cancer Drugs to Combat COVID-19
https://www.onclive.com/view/teaching-an-old-dog-new-tricks-repurposing-cancer-drugs-to-combat-covid-19

Feb 5th, 2021 - In response to the novel coronavirus disease 2019 (COVID-19) pandemic, investigators around the world channeled their efforts into acquiring a better understanding of the virus so that they could rapidly identify any weapons that may be used in th...

Dr. Uldrick on Rituximab Plus Liposomal Doxorubicin in HIV-Infected Patients With KSHV-MCD
https://www.onclive.com/view/dr-uldrick-on-rituximab-plus-liposomal-doxorubicin-in-hiv-infected-patients-with-kshv-mcd

Dec 20th, 2020 - Thomas S. Uldrick, MD, staff clinician, HIV and AIDS Malignancy Branch, Center for Cancer Research at the National Institutes of Health, discusses long-term data from a study examining rituximab plus liposomal doxorubicin in HIV-infected patients ...

Checkpoint Blockade Therapy Clears Safety Hurdle for Patients With HIV and Cancer
https://www.onclive.com/view/checkpoint-blockade-therapy-clears-safety-hurdle-for-patients-with-hiv-and-cancer

Nov 13th, 2020 - Thomas S. Uldrick, MD Although there has been reluctance among oncology researchers to administer immunotherapy to patients with HIV who develop cancer, early signals from a small clinical trial suggest that such a strategy may be safe in certain...

New guidelines for idiopathic multicentric Castleman disease
https://www.mdedge.com/hematology-oncology/article/184660/related-issues/new-guidelines-idiopathic-multicentric-castleman-disease
Andrew D. Bowser

Oct 10th, 2018 - Photo from Penn Medicine David C. Fajgenbaum, MD The anti-IL-6 antibody siltuximab is central to first-line treatment of idiopathic multicentric Castleman disease (iMCD), according to new guidelines on iMCD published in Blood.

Rare type of MCL mimics Castleman disease
https://www.mdedge.com/fedprac/article/148854/hematologic-malignancies/rare-type-mcl-mimics-castleman-disease
Andrew D. Bowser

Oct 6th, 2017 - A rare type of mantle cell lymphoma (MCL) has features that are similar to those of Castleman disease, according to a recent report based on three patient cases. Lymph node biopsies for these patients initially indicated histologic features consis.

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Patient Education  1 results see all →