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About 3,285 results

ALLMedicine™ Lymphoproliferative Disorders Center

Research & Reviews  1,171 results

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
https://clinicaltrials.gov/ct2/show/NCT03663933

Jun 24th, 2022 - Background: Disorders of T-cell proliferation and/or dysregulation (TCP/D) can lead to T-cell lymphoproliferative disorders, autoimmunity, infection, and aberrant immune activation with resulting organ dysfunction, morbidity, and mortality. Alloge...

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas
https://clinicaltrials.gov/ct2/show/NCT03258567

Jun 24th, 2022 - BACKGROUND: Epstein-Barr virus (EBV) is a chronic viral infection associated with a heterogeneous group of lymphoproliferative disorders (LPD) and non-Hodgkin lymphomas (NHL). The shared pathobiology of EBV-positive LPDs and NHLs includes a defect...

A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB)
https://clinicaltrials.gov/ct2/show/NCT04138875

Jun 23rd, 2022 - Post-Transplant Lymphoproliferative Disorders (PTLD) are defined by the revised 2017 edition of the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues as "lymphoid or plasmacytic proliferations that develop as a consequence of im...

Early- and late onset post-transplant lymphoproliferative disorders (PTLD) among adult ...
https://doi.org/10.1111/ejh.13815
European Journal of Haematology; Abdulovski R, Møller DL et. al.

Jun 21st, 2022 - Post-transplant lymphoproliferative disorder (PTLD) in solid organ transplant recipients has a high mortality and may present early (<2 years) or late (≥ 2 years) post-transplantation. We investigated the clinical characteristics of early and late...

The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT05004259

Jun 21st, 2022 - Autoimmune Hemolytic Anemia (AIHA) is a hematologic disorder in which the red blood cells are targeted and destroyed by autoantibodies produced by the immune system, specifically B-cells and plasma cells. It can be either idiopathic, or secondary ...

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Guidelines  4 results

T-Cell Lymphomas, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2022.0015
Journal of the National Comprehensive Cancer Network : JN... Horwitz SM, Ansell S et. al.

Mar 12th, 2022 - Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoproliferative disorders arising from mature T cells, accounting for about 10% of non-Hodgkin lymphomas. PTCL-not otherwise specified is the most common subtype, followed by ang...

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.
https://doi.org/10.1002/art.41752
Arthritis & Rheumatology (Hoboken, N.J.); Fraenkel L, Bathon JM et. al.

Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grad...

Non-Hodgkin's lymphomas, version 4.2014.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839265
Journal of the National Comprehensive Cancer Network : JN... Zelenetz AD, Gordon LI et. al.

Sep 6th, 2014 - Non-Hodgkin's lymphomas (NHL) are a heterogeneous group of lymphoproliferative disorders originating in B lymphocytes, T lymphocytes, or natural killer cells. Mantle cell lymphoma (MCL) accounts for approximately 6% of all newly diagnosed NHL case...

Non-Hodgkin's lymphomas, version 2.2014.
https://doi.org/10.6004/jnccn.2014.0086
Journal of the National Comprehensive Cancer Network : JN... Zelenetz AD, Gordon LI et. al.

Jun 14th, 2014 - Non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B lymphocytes, T lymphocytes, or natural killer cells. Follicular lymphoma (FL) is the most common subtype of indolent NHL, accounting for app...

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Clinicaltrials.gov  77 results

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
https://clinicaltrials.gov/ct2/show/NCT03663933

Jun 24th, 2022 - Background: Disorders of T-cell proliferation and/or dysregulation (TCP/D) can lead to T-cell lymphoproliferative disorders, autoimmunity, infection, and aberrant immune activation with resulting organ dysfunction, morbidity, and mortality. Alloge...

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas
https://clinicaltrials.gov/ct2/show/NCT03258567

Jun 24th, 2022 - BACKGROUND: Epstein-Barr virus (EBV) is a chronic viral infection associated with a heterogeneous group of lymphoproliferative disorders (LPD) and non-Hodgkin lymphomas (NHL). The shared pathobiology of EBV-positive LPDs and NHLs includes a defect...

A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB)
https://clinicaltrials.gov/ct2/show/NCT04138875

Jun 23rd, 2022 - Post-Transplant Lymphoproliferative Disorders (PTLD) are defined by the revised 2017 edition of the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues as "lymphoid or plasmacytic proliferations that develop as a consequence of im...

The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT05004259

Jun 21st, 2022 - Autoimmune Hemolytic Anemia (AIHA) is a hematologic disorder in which the red blood cells are targeted and destroyed by autoantibodies produced by the immune system, specifically B-cells and plasma cells. It can be either idiopathic, or secondary ...

An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas
https://clinicaltrials.gov/ct2/show/NCT05011058

Jun 10th, 2022 - Patients with EBV-associated lymphomas have inferior outcomes with standard-of-care therapies compared to those with EBV-negative disease. Nanatinostat is a selective class I HDAC inhibitor which induces EBV lytic phase protein generation, activat...

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News  61 results

ITP Armamentarium Expands With the Hope of Limiting Long-Term Steroid Exposure
https://www.onclive.com/view/itp-armamentarium-expands-with-the-hope-of-limiting-long-term-steroid-exposure

Apr 18th, 2022 - Although patients with primary and secondary immune thrombocytopenia (ITP) can derive good responses from corticosteroids, long-term exposure to steroids is associated with unique adverse effects (AEs), said Kanwarpal S. Kahlon, MD, who added that...

Vaccinated Blood Cancer Patients Still at Risk for Severe COVID-19
https://www.medpagetoday.com/hematologyoncology/hematology/95535

Nov 8th, 2021 - Patients with hematologic malignancies who had breakthrough COVID-19 infections still had high risk for severe or critical disease, according to a registry-based study. Out of 113 reported cases of SARS-CoV-2 infection post-vaccination in people w...

Infusion shown effective for acquired von Willebrand disease
https://www.mdedge.com/hematology-oncology/article/244070/bleeding-disorders/infusion-shown-effective-acquired-von
Mark S. Lesney, PhD

Aug 10th, 2021 - Acquired von Willebrand disease (aVWD) is a rare and serious condition associated with lymphoproliferative disorders, malignancy, autoimmune disorders, and cardiovascular disease. It is most commonly caused by monoclonal gammopathy of undetermined.

Nodule on the Neck
https://www.mdedge.com/dermatology/article/239893/dermatopathology/nodule-neck
Malan Kern, MD, Kelsey Parks, BS et. al.

May 11th, 2021 - The Diagnosis: Primary Cutaneous Anaplastic Large Cell Lymphoma Microscopic analysis showed a dense proliferation of mononuclear cells filling and expanding the dermis with focal epidermotropism (Figure 1). Immunohistochemistry demonstrated strong.

Large circular thigh rash
https://www.mdedge.com/familymedicine/article/233080/dermatology/large-circular-thigh-rash
MDedge Family Medicine;

Dec 7th, 2020 - This patient had the deep form of erythema annulare centrifugum (EAC). As the name implies, it manifests as an expanding, red circular pattern that often clears in the middle.

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Patient Education  1 results see all →