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About 5,939 results

ALLMedicine™ Aplastic Anemia Center

Research & Reviews  2,795 results

Unexpected pure red series aplastic anemia secondary to pembrolizumab treatment: a case...
https://doi.org/10.1097/CMR.0000000000000724
Melanoma Research; Meri-Abad M, Cunquero Tomás AJ et. al.

Feb 24th, 2021 - Pembrolizumab is a treatment that has shown a survival benefit in patients with metastatic melanoma. Programmed death receptor 1 inhibitors are new therapeutic agents that produce clinical responses with a more manageable profile of adverse effect...

Haplo-identical or mismatched unrelated donor hematopoietic cell transplantation for Fa...
https://doi.org/10.1002/ajh.26135
American Journal of Hematology; Zubicaray J, Pagliara D et. al.

Feb 19th, 2021 - Allogeneic hematopoietic cell transplantation (HCT) is the only curative option for bone marrow failure or hematopoietic malignant diseases for Fanconi anemia (FA) patients. Although results have improved over the last decades, reaching more than ...

Thrombopoietin Promotes Cell Proliferation and Attenuates Apoptosis of Aplastic Anemia ...
https://doi.org/10.1177/0963689720980367
Cell Transplantation; Qian J, Cao X et. al.

Feb 15th, 2021 - The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate t...

Eltrombopag Add-on Treatment in a Child With Fanconi Aplastic Anemia Awaiting Hematopoi...
https://doi.org/10.1097/MPH.0000000000002082
Journal of Pediatric Hematology/oncology; Aydin Koker S, Çalişkan Polat A

Feb 9th, 2021 - Fanconi aplastic anemia (FAA) is a rare inherited bone marrow failure disorder characterized by congenital defects and pancytopenia. Hematopoietic stem cell transplantation (HSCT) is a curative treatment for patients with FAA due to the risk of ca...

Bariatric Embolization in the Treatment of Patients with a Body Mass Index Between 30 a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304103
Cardiovascular and Interventional Radiology; Levigard RB, Serrão H et. al.

Feb 2nd, 2021 - Germline loss-of-function mutations in the transcription factor signal transducer and activator of transcription 3 (STAT3) cause immunodeficiency, whereas somatic gain-of-function mutations in STAT3 are associated with large granular lymphocytic l...

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Guidelines  2 results

Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the ...
https://doi.org/10.1016/j.bcmd.2015.03.007
Blood Cells, Molecules & Diseases; Barone A, Lucarelli A et. al.

May 15th, 2015 - Acquired aplastic anemia (AA) is a rare heterogeneous disease characterized by pancytopenia and hypoplastic bone marrow. The incidence is 2-3/million inhabitants/year, in Europe, but higher in East Asia. Survival in severe aplastic anemia (SAA) ha...

Diagnostic criteria to distinguish hypocellular acute myeloid leukemia from hypocellula...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635414
Haematologica Bennett JM, Orazi A

Jan 15th, 2009 - Members of the French-American-British Cooperative Leukemia Working Group met to review cases of aplastic anemia, hypocellular myelodysplastic syndrome and hypocellular acute myeloid leukemia. Criteria were proposed and modified following three wo...

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Drugs  91 results see all →

Clinicaltrials.gov  2,943 results

Unexpected pure red series aplastic anemia secondary to pembrolizumab treatment: a case...
https://doi.org/10.1097/CMR.0000000000000724
Melanoma Research; Meri-Abad M, Cunquero Tomás AJ et. al.

Feb 24th, 2021 - Pembrolizumab is a treatment that has shown a survival benefit in patients with metastatic melanoma. Programmed death receptor 1 inhibitors are new therapeutic agents that produce clinical responses with a more manageable profile of adverse effect...

Haplo-identical or mismatched unrelated donor hematopoietic cell transplantation for Fa...
https://doi.org/10.1002/ajh.26135
American Journal of Hematology; Zubicaray J, Pagliara D et. al.

Feb 19th, 2021 - Allogeneic hematopoietic cell transplantation (HCT) is the only curative option for bone marrow failure or hematopoietic malignant diseases for Fanconi anemia (FA) patients. Although results have improved over the last decades, reaching more than ...

Thrombopoietin Promotes Cell Proliferation and Attenuates Apoptosis of Aplastic Anemia ...
https://doi.org/10.1177/0963689720980367
Cell Transplantation; Qian J, Cao X et. al.

Feb 15th, 2021 - The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate t...

Eltrombopag Add-on Treatment in a Child With Fanconi Aplastic Anemia Awaiting Hematopoi...
https://doi.org/10.1097/MPH.0000000000002082
Journal of Pediatric Hematology/oncology; Aydin Koker S, Çalişkan Polat A

Feb 9th, 2021 - Fanconi aplastic anemia (FAA) is a rare inherited bone marrow failure disorder characterized by congenital defects and pancytopenia. Hematopoietic stem cell transplantation (HSCT) is a curative treatment for patients with FAA due to the risk of ca...

Bariatric Embolization in the Treatment of Patients with a Body Mass Index Between 30 a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304103
Cardiovascular and Interventional Radiology; Levigard RB, Serrão H et. al.

Feb 2nd, 2021 - Germline loss-of-function mutations in the transcription factor signal transducer and activator of transcription 3 (STAT3) cause immunodeficiency, whereas somatic gain-of-function mutations in STAT3 are associated with large granular lymphocytic l...

see more →

News  89 results

Chimerism and the use of fludarabine associated with secondary graft failure in aplastic anemia
https://www.mdedge.com/hematology-oncology/article/218544/anemia/chimerism-and-use-fludarabine-associated-secondary-graft?channel=39313
Mark S. Lesney

Mar 6th, 2020 - Inferior overall survival was observed in patients with aplastic anemia who had mixed or complete recipient-type chimerism or complete donor chimerism after hematopoietic stem cell transplantation (HSCT), according to the results of a registry dat.

Aplastic Anemia: Diagnosis and Treatment
https://www.mdedge.com/jcomjournal/article/208651/hematology/aplastic-anemia-diagnosis-and-treatment/page/0/4?channel=325

Oct 7th, 2019 - Treatment of Acquired Aplastic Anemia Supportive Care While the workup and treatment plan are being established, attention should be directed at supportive care for prevention of complications. The most common complications leading to death in pat.

Combination Immunotherapy Leading to Severe Hepatotoxicity and Fatal Aplastic Anemia: Case Report and Review of the Literature
https://www.mdedge.com/fedprac/avaho/article/207600/mixed-topics/combination-immunotherapy-leading-severe-hepatotoxicity?channel=53
Dominick A, Fields-Meehan JE et. al.

Sep 5th, 2019 - Background: Dual immune checkpoint blockade (DICB) is utilized for a variety of malignancies. These therapies have a unique and often unpredictable side effect profile compared to conventional chemotherapy.

Aplastic Anemia: Current Treatment
https://www.mdedge.com/hematology-oncology/article/192810/anemia/aplastic-anemia-current-treatment/page/0/2

Jan 23rd, 2019 - Immunosuppressive Therapy For patients without an HLA-matched sibling donor or those who are older than 50 years of age, immunosuppressive therapy is the first-line therapy. ATG and cyclosporine A are the treatments of choice.

Aplastic Anemia: Evaluation and Diagnosis
https://www.mdedge.com/hematology-oncology/article/192807/anemia/aplastic-anemia-evaluation-and-diagnosis/page/0/2

Jan 18th, 2019 - In addition to peripheral blood findings, bone marrow biopsy is essential for the diagnosis, and should demonstrate a markedly hypocellular marrow (cellularity < 25%), occasionally with an increase in T lymphocytes. 7,39 Because marrow cellularity.

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Patient Education  19 results see all →