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About 90 results

ALLMedicine™ Sideroblastic Anemias Center

Research & Reviews  45 results

Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital siderobla...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524500
The Journal of Clinical Investigation; Crispin A, Guo C et. al.

Jul 7th, 2020 - The congenital sideroblastic anemias (CSAs) can be caused by primary defects in mitochondrial iron-sulfur (Fe-S) cluster biogenesis. HSCB (heat shock cognate B), which encodes a mitochondrial cochaperone, also known as HSC20 (heat shock cognate pr...

Treatment of Acquired Sideroblastic Anemias.
https://doi.org/10.1016/j.hoc.2019.11.002
Hematology/oncology Clinics of North America; Mangaonkar AA, Patnaik MM

Feb 24th, 2020 - Sideroblastic anemias are a heterogeneous group of disorders unified by the presence of abnormal erythroid precursors with perinuclear mitochondrial iron deposition in the bone marrow. Based on etiology, they are classified into clonal and nonclon...

Causes and pathophysiology of the sideroblastic anemias
https://www.uptodate.com//contents/causes-and-pathophysiology-of-the-sideroblastic-anemias
Sylvia S Bottomley

INTRODUCTION Sideroblastic anemias are anemias in which ring sideroblasts are present on the bone marrow aspirate smear stained for iron with Prussian blue. Ring sideroblasts are found in diverse circumstances, which underscores a broad spectrum o...

Sideroblastic anemias: Diagnosis and management
https://www.uptodate.com//contents/sideroblastic-anemias-diagnosis-and-management
Sylvia S Bottomley

INTRODUCTION The sideroblastic anemias comprise a wide spectrum of relatively uncommon heritable and acquired erythropoietic disorders that are due to various abnormalities in heme synthesis and mitochondrial function ( table 1 ). ●In many of thes...

The molecular genetics of sideroblastic anemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318428
Blood Ducamp S, Fleming MD

Nov 7th, 2018 - The sideroblastic anemias (SAs) are a group of inherited and acquired bone marrow disorders defined by pathological iron accumulation in the mitochondria of erythroid precursors. Like most hematological diseases, the molecular genetic basis of the...

see more →

Clinicaltrials.gov  45 results

Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital siderobla...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524500
The Journal of Clinical Investigation; Crispin A, Guo C et. al.

Jul 7th, 2020 - The congenital sideroblastic anemias (CSAs) can be caused by primary defects in mitochondrial iron-sulfur (Fe-S) cluster biogenesis. HSCB (heat shock cognate B), which encodes a mitochondrial cochaperone, also known as HSC20 (heat shock cognate pr...

Treatment of Acquired Sideroblastic Anemias.
https://doi.org/10.1016/j.hoc.2019.11.002
Hematology/oncology Clinics of North America; Mangaonkar AA, Patnaik MM

Feb 24th, 2020 - Sideroblastic anemias are a heterogeneous group of disorders unified by the presence of abnormal erythroid precursors with perinuclear mitochondrial iron deposition in the bone marrow. Based on etiology, they are classified into clonal and nonclon...

Causes and pathophysiology of the sideroblastic anemias
https://www.uptodate.com//contents/causes-and-pathophysiology-of-the-sideroblastic-anemias
Sylvia S Bottomley

INTRODUCTION Sideroblastic anemias are anemias in which ring sideroblasts are present on the bone marrow aspirate smear stained for iron with Prussian blue. Ring sideroblasts are found in diverse circumstances, which underscores a broad spectrum o...

Sideroblastic anemias: Diagnosis and management
https://www.uptodate.com//contents/sideroblastic-anemias-diagnosis-and-management
Sylvia S Bottomley

INTRODUCTION The sideroblastic anemias comprise a wide spectrum of relatively uncommon heritable and acquired erythropoietic disorders that are due to various abnormalities in heme synthesis and mitochondrial function ( table 1 ). ●In many of thes...

The molecular genetics of sideroblastic anemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318428
Blood Ducamp S, Fleming MD

Nov 7th, 2018 - The sideroblastic anemias (SAs) are a group of inherited and acquired bone marrow disorders defined by pathological iron accumulation in the mitochondria of erythroid precursors. Like most hematological diseases, the molecular genetic basis of the...

see more →