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About 53,403 results

ALLMedicine™ Anemia Center

Research & Reviews  16,782 results

The neglected members of the family: non-BRCA mutations in the Fanconi anemia/BRCA path...
https://doi.org/10.1093/humupd/dmab045
Human Reproduction Update; Vanni VS, Campo G et. al.

Jan 20th, 2022 - BReast CAncer (BRCA) genes are extensively studied in the context of fertility and reproductive aging. BRCA proteins are part of the DNA repair Fanconi anemia (FA)/BRCA pathway, in which more than 20 proteins are implicated. According to which gen...

Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88.
https://doi.org/10.4049/jimmunol.2100784
Journal of Immunology (Baltimore, Md. : 1950); Soldatenko A, Hoyt LR et. al.

Jan 19th, 2022 - RBC transfusion therapy is essential for the treatment of anemia. A serious complication of transfusion is the development of non-ABO alloantibodies to polymorphic RBC Ags; yet, mechanisms of alloantibody formation remain unclear. Storage of mouse...

HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.
https://doi.org/10.1182/blood.2021012048
Blood Dulmovits BM, Tang Y et. al.

Jan 19th, 2022 - Anemia of inflammation, also known as anemia of chronic disease, is refractory to erythropoietin (EPO) treatment, but the mechanisms underlying the EPO-refractory state are unclear. Here, we demonstrate that high mobility group box-1 protein (HMGB...

Clinical impact of vivax malaria: A collection review.
https://doi.org/10.1371/journal.pmed.1003890
PLoS Medicine; Phyo AP, Dahal P et. al.

Jan 19th, 2022 - Plasmodium vivax infects an estimated 7 million people every year. Previously, vivax malaria was perceived as a benign condition, particularly when compared to falciparum malaria. Reports of the severe clinical impacts of vivax malaria have been i...

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Guidelines  25 results

Controversies in optimal anemia management: conclusions from a Kidney Disease: Improvin...
https://doi.org/10.1016/j.kint.2021.03.020
Kidney International; Babitt JL, Eisenga MF et. al.

Apr 12th, 2021 - In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and associated with significant adverse consequences. In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) issued an anemia guideline for managing the diagnosis,...

Spotlight: Gastrointestinal Evaluation of Iron Deficiency Anemia.
https://doi.org/10.1053/j.gastro.2020.08.036
Gastroenterology Ko CW, Siddique SM et. al.

Aug 31st, 2020 - Spotlight: Gastrointestinal Evaluation of Iron Deficiency Anemia.|2020|Ko CW,Siddique SM,Patel A,Harris A,Altayar O,|blood,diagnosis,etiology,standards,standards,standards,diagnostic imaging,metabolism,pathology,standards,blood,complications,diagn...

GI Evaluation of Iron Deficiency Anemia: Clinical Decision Support Tool.
https://doi.org/10.1053/j.gastro.2020.08.043
Gastroenterology

Aug 31st, 2020 - GI Evaluation of Iron Deficiency Anemia: Clinical Decision Support Tool.|2020| ,|blood,diagnosis,etiology,standards,methods,standards,standards,diagnostic imaging,metabolism,pathology,standards,blood,complications,diagnosis,pathology,analysis,diag...

AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency ...
https://doi.org/10.1053/j.gastro.2020.06.046
Gastroenterology Ko CW, Siddique SM et. al.

Aug 19th, 2020 - AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia.|2020|Ko CW,Siddique SM,Patel A,Harris A,Sultan S,|blood,diagnosis,epidemiology,etiology,standards,standards,diagnostic imaging,metabolism,pathology,stan...

Management of Cancer-Associated Anemia With Erythropoiesis-Stimulating Agents: ASCO/ASH...
https://doi.org/10.1200/JCO.18.02142
Journal of Clinical Oncology : Official Journal of the Am... Bohlius J, Bohlke K et. al.

Apr 11th, 2019 - To update the American Society of Clinical Oncology (ASCO)/American Society of Hematology (ASH) recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. PubMed and the Cochrane Library were searched for randomiz...

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Drugs  732 results see all →

Clinicaltrials.gov  943 results

Dietary Intake, Health and Micronutrient Status in Haiti
https://clinicaltrials.gov/ct2/show/NCT04034381

Jan 14th, 2022 - Women of reproductive age and young children are especially vulnerable to micronutrient deficiencies which may lead to life-long disabilities. In Haiti, deficiencies in micronutrients such as iron, zinc, and vitamin A, are likely prevalent, but re...

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma
https://clinicaltrials.gov/ct2/show/NCT04933539

Jan 14th, 2022 - Background: Smoldering multiple myeloma (SMM) is a precursor condition to MM defined by the clinical parameters of M-protein >=3.0 g/dL or bone marrow plasma cells >=10%, and absence of end organ disease. Patients with high-risk SMM have a risk of...

Lidocaine in ERAS for FESS
https://clinicaltrials.gov/ct2/show/NCT03047070

Jan 14th, 2022 - Functional endoscopic sinus surgery (FESS) is a commonly performed procedure in the head and neck field. It is known that bleeding during FESS can affect directly to the visibility of safe landmarks and surgical outcomes. Use of vasoactive drugs t...

Quality Assurance on Anemia Management in Patients With Solid Tumors and Malignant Lymphoma
https://clinicaltrials.gov/ct2/show/NCT05190263

Jan 13th, 2022 - Health care structure analysis and recruitment (phase 1): In a first step, data on care facilities treating patients in the above indica-tions in Germany will be collected (gastroenterology, gynecology, hema-tology/oncology, and pneumology hospita...

A Study to Learn More About the Long-term Safety and Effectiveness of Molidustat as a Treatment for Japanese Men and Women With Renal Anemia
https://clinicaltrials.gov/ct2/show/NCT04899661

Jan 12th, 2022 - In this study, the researchers want to learn more about the safety and effectiveness of Molidustat in Japanese men and women who have renal anemia, a condition in which the kidneys do not make enough of a hormone that helps the body make new red b...

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News  2,754 results

Sugemalimab Boosts Outcomes in NSCLC
https://www.medpagetoday.com/hematologyoncology/lungcancer/96754

Jan 19th, 2022 - The anti-PD-L1 antibody sugemalimab significantly prolonged progression-free survival (PFS) in patients with unresectable or metastatic non-small cell lung cancer (NSCLC), results from two phase III trials conducted in China showed. In an interim ...

Anemia in Astronauts Could Be a Challenge for Space Missions
https://www.medscape.com/viewarticle/966648

Jan 17th, 2022 - (Reuters) - The next "giant leap" for humans may be a trip to Mars, but having enough oxygen-carrying red blood cells for the journey might present a challenge, new research suggests. Even space tourists lining up for short trips might have to sta...

FDA Accepts BLA for Tislelizumab in Esophageal Squamous Cell Carcinoma
https://www.onclive.com/view/fda-accepts-bla-for-tislelizumab-in-esophageal-squamous-cell-carcinoma

Jan 14th, 2022 - The FDA has accepted for review a biologics license application (BLA) for tislelizumab (BGB-A317) as a potential therapeutic option in patients with unresectable recurrent locally advanced or metastatic esophageal squamous cell carcinoma (ESCC) fo...

Ibrutinib/Rituximab Combo Represents Effective Chemo-Free Option for Elderly Patients with MCL
https://www.onclive.com/view/ibrutinib-rituximab-combo-represents-effective-chemo-free-option-for-elderly-patients-with-mcl

Jan 14th, 2022 - The combination of ibrutinib (Imbruvica) and rituximab (Rituxan) produced a high overall response rate (ORR) and durable survival in elderly patients with mantle cell lymphoma (MCL), according to data from a phase 2 ENRICH trial (NCT0180567) publi...

Fast Five Quiz: Relapsed/Refractory Multiple Myeloma
https://www.medscape.com/viewarticle/962961

Jan 11th, 2022 - Multiple myeloma is a plasma cell cancer characterized by proliferation of monoclonal plasma cells in bone marrow, leading to an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell...

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Patient Education  125 results see all →