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About 263 results

ALLMedicine™ Macrocytosis Center

Research & Reviews  89 results

Clinical Presentation of Subacute Combined Degeneration in a Patient With Chronic B12 Deficiency
https://www.mdedge.com/fedprac/article/252920/neurology/clinical-presentation-subacute-combined-degeneration-patient
Nathan Kostick, Evan Chen et. al.

Mar 21st, 2022 - Subacute combined degeneration (SCD) is an acquired neurologic complication of vitamin B12 (cobalamin) or, rarely, vitamin B9 (folate) deficiency. SCD is characterized by progressive demyelination of the dorsal and lateral spinal cord, resulting i.

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor
https://clinicaltrials.gov/ct2/show/NCT02678533

Dec 22nd, 2021 - Fanconi anemia is an autosomal recessive disease with an average survival of around 24 years old. The number of cells producted by bone marrow decreases around 5-10 years old. Hematological symptoms occur around 7 years old. 80% of patients with F...

Bone Marrow Failure Clinical Presentation
https://emedicine.medscape.com/article/199003-clinical

Dec 6th, 2021 - History Patients with bone marrow failure present with the consequences of low blood counts. Low platelet counts predispose patients to spontaneous bleeding in the skin and mucous membranes. Neutropenia places the patient at risk for serious infec...

Bone Marrow Failure Workup
https://emedicine.medscape.com/article/199003-workup

Dec 6th, 2021 - Approach Considerations Bone marrow failure can present as isolated cytopenias such as pure red cell aplasia or amegakaryocytic thrombocytopenia; or with pancytopenia, as in aplastic anemia. Peripheral blood findings Anemia is common, with red cel...

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Drugs  6 results see all →

Clinicaltrials.gov  3 results

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor
https://clinicaltrials.gov/ct2/show/NCT02678533

Dec 22nd, 2021 - Fanconi anemia is an autosomal recessive disease with an average survival of around 24 years old. The number of cells producted by bone marrow decreases around 5-10 years old. Hematological symptoms occur around 7 years old. 80% of patients with F...

Etiopathogenesis of Anemia in Chronic Liver Disease
https://clinicaltrials.gov/ct2/show/NCT04622449

Sep 28th, 2021 - Common causes of anemia include acute and chronic blood loss due to upper gastrointestinal (GI) bleeding, malnutrition, hemolysis, hypersplenism secondary to portal hypertension, and impaired coagulation. Alcohol causes anemia by its direct bone m...

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100
https://clinicaltrials.gov/ct2/show/NCT00479115

Oct 30th, 2020 - Fanconi anemia is a rare autosomal recessive syndrome comprised of progressive bone marrow failure, congenital anomalies and a predisposition to malignancy. The heterozygote rate in the United States may be as high as 1 in 300. The mean age for th...

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News  7 results

Clinical Presentation of Subacute Combined Degeneration in a Patient With Chronic B12 Deficiency
https://www.mdedge.com/fedprac/article/252920/neurology/clinical-presentation-subacute-combined-degeneration-patient
Nathan Kostick, Evan Chen et. al.

Mar 21st, 2022 - Subacute combined degeneration (SCD) is an acquired neurologic complication of vitamin B12 (cobalamin) or, rarely, vitamin B9 (folate) deficiency. SCD is characterized by progressive demyelination of the dorsal and lateral spinal cord, resulting i.

Diverse Set of Biomarkers Tied to Increased MDD Incidence
https://www.medscape.com/viewarticle/954678

Jul 13th, 2021 - Takeaway In a large community-based cohort study, biological markers of liver, kidney and endocrine dysfunction, innate immunity, anaemia and macrocytosis were associated with an increased 5-year incidence of major depressive disorder (MDD). Why t...

Ensuring an Accurate Diagnosis
https://www.onclive.com/view/ensuring-an-accurate-diagnosis

Apr 2nd, 2021 - Amy DeZern, MD, MHS: From your perspective, Dr Komrokji, what do community physicians need to look out for in terms of recognizing some of these symptoms and making sure we bring a patient to their accurate diagnosis? Rami Komrokji, MD: As you me...

EU Panel Recommends Hydroxycarbamide for Sickle Cell Disease
https://www.medscape.com/viewarticle/912306

Apr 26th, 2019 - The European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use recommended granting marketing authorization for hydroxycarbamide (Xromi, Nova Laboratories Ireland Limited) for the prevention of vaso-occlusive complications ...

EU Panel Recommends Hydroxycarbamide for Sickle Cell Disease
https://www.staging.medscape.com/viewarticle/912306

Apr 26th, 2019 - The European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use recommended granting marketing authorization for hydroxycarbamide (Xromi, Nova Laboratories Ireland Limited) for the prevention of vaso-occlusive complications ...

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