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About 968 results

ALLMedicine™ Methemoglobinemia Center

Research & Reviews  275 results

Methemoglobinemia due to use of poppers: a case report.
https://doi.org/10.1186/s13256-022-03475-8 10.2165/00002018-199614060-00005 10.2165/00139709-200322010-00003 10.1016/j.drugpo.2018.11.011 10.1051/ata/2001007 10.1016/0929-693X(96)81305-4 10.1016/j.therap.2018.09.050 10.1080/02791072.2020.1791373
Journal of Medical Case Reports; Sonck E, Bourmanne E et. al.

Jun 21st, 2022 - Methemoglobinemia is an excess of oxidized hemoglobin in the blood, affecting oxygen transportation. It is characterized by central cyanosis that does not respond to oxygen therapy. Prognosis is excellent when treated adequately and rapidly. We pr...

Near-fatal pediatric methemoglobinemia secondary to intentional sodium nitrite ingestio...
https://doi.org/10.1016/j.ajem.2022.05.051
The American Journal of Emergency Medicine; Sajko N, Finn K et. al.

Jun 13th, 2022 - Methemoglobinemia is the result of inappropriate oxidation of hemoglobin iron groups, leading to a failure of oxygen transport and delivery, resulting in a clinical state of refractory hypoxia. Methemoglobin levels above 70% are often considered f...

Safety and practicality of high dose inhaled nitric oxide in emergency department COVID...
https://doi.org/10.1016/j.ajem.2022.04.052
The American Journal of Emergency Medicine; Strickland B, Albala L et. al.

May 28th, 2022 - Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator and mild bronchodilator that has been shown to improve systemic oxygenation, but has rarely been administered in the Emergency Department (ED). In addition to its favorable pulmonary ...

Elevated methemoglobin levels in patients treated with hydroxocobalamin: a case series ...
https://doi.org/10.1080/15563650.2022.2072315
Clinical Toxicology (Philadelphia, Pa.); Kiernan EA, Carpenter JE et. al.

May 14th, 2022 - Historically, the first step in treating cyanide (CN-) toxicity utilized antidotes to induce methemoglobinemia. This is concerning in patients who are already hypoxemic or have elevated carboxyhemoglobin. Hydroxocobalamin (OHCbl) is now the first-...

Acquired methemoglobinemia in children presenting to Italian pediatric emergency depart...
https://doi.org/10.1080/15563650.2022.2061986
Clinical Toxicology (Philadelphia, Pa.); Raucci U, Stanco M et. al.

Apr 14th, 2022 - Methemoglobinemia (MetHb) is a rare inherited or acquired cause of cyanosis in children. Owing to its rarity, case reports and case series are mostly available in the current literature. This study reports data on a large sample of children with a...

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Guidelines  2 results

Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for rasburicase t...
https://doi.org/10.1038/clpt.2014.97
Clinical Pharmacology and Therapeutics; Relling MV, McDonagh EM et. al.

May 3rd, 2014 - Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with development of acute hemolytic anemia (AHA) induced by a number of drugs. We provide guidance as to which G6PD genotypes are associated with G6PD deficiency in males and female...

ASRA practice advisory on local anesthetic systemic toxicity.
https://doi.org/10.1097/AAP.0b013e3181d22fcd
Regional Anesthesia and Pain Medicine; Neal JM, Bernards CM et. al.

Mar 11th, 2010 - The American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity assimilates and summarizes current knowledge regarding the prevention, diagnosis, and treatment of this potentially fatal complic...

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Drugs  72 results see all →

Clinicaltrials.gov  18 results

Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
https://clinicaltrials.gov/ct2/show/NCT05131295

Nov 23rd, 2021 - A prospective, analytical, randomized, double-blinded, placebo-controlled clinical trial was realized. Participants suffering from aneurysmal subarachnoid hemorrhage (SAH), matching the inclusion criteria, were randomly assigned using a computer-d...

Acquired Methemoglobinemia Observational Registry
https://clinicaltrials.gov/ct2/show/NCT03542760

Jul 8th, 2021 - This prospective, observational registry aims to collect real-world data regarding the safety and efficacy of ProvayBlue® (methylene blue 0.5%) used according to normal standard of care for the treatment of acquired methemoglobinemia. Methylene bl...

MEthylene Blue In Patients With Acquired Methemoglobinemia
https://clinicaltrials.gov/ct2/show/NCT03395223

Mar 10th, 2021 - This is an open label, uncontrolled, Phase 4 study including 10 patients who present in hospital/urgent care setting with acquired methemoglobinemia. The population may include pediatric and adult patients (males and females of all ages are includ...

Acute Safety and Acceptability Study of Experimental Device RD19 for Protection From Human Respiratory Disease Pathogens
https://clinicaltrials.gov/ct2/show/NCT04557826

Feb 4th, 2021 - This first-in-man (FIM) phase I study will evaluate the acute safety, tolerability,and acceptability of the investigational RD19 device among 25 healthy volunteers between the age of 18 and 45. Based on the results of numerous preclinical studies,...

Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.
https://clinicaltrials.gov/ct2/show/NCT01766999

Nov 3rd, 2020 - Tumescent local anesthesia is a procedure which is frequently performed for plastic cosmetic surgical procedures such as liposuction. The subcutaneous adipose tissue is infiltrated with large volumes of a solution which also contain local anesthet...

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News  20 results

FDA Drug Safety Communication: FDA recommends not using lidocaine to treat teething pain and requires new Boxed Warning
https://www.fda.gov/Drugs/DrugSafety/ucm402240.htm

The U.S. Food and Drug Administration (FDA) warns that prescription oral viscous lidocaine 2 percent solution should not be used to treat infants and children with teething pain.  We are requiring a new Boxed Warning, FDA’s strongest warning, to b...

FDA Warns on OTC Teething Products with Benzocaine
https://www.medpagetoday.com/pediatrics/generalpediatrics/73066

May 23rd, 2018 - WASHINGTON -- Benzocaine-containing products sold over the counter to relieve babies' teething pain are too risky and should no longer be sold, the FDA said Wednesday. The agency "is asking companies to stop selling these products for such use," a...

Stop Using OTC Benzocaine Teething Products, FDA Says
https://www.medscape.com/viewarticle/897136

May 23rd, 2018 - The US Food and Drug Administration (FDA) is warning consumers to immediately stop using benzocaine-containing over-the-counter drug products, including those used to treat teething pain, in infants and children under 2 years of age as they can po...

Methemoglobinemia in an HIV patient
https://www.mdedge.com/ccjm/article/159301/hematology/methemoglobinemia-hiv-patient?channel=325
Riva Raiker, MD, William C. Lippert, MD, MPH et. al.

Mar 1st, 2018 - A 45-year-old man with known human immunodeficiency virus infection presented with a 5-day history of dyspnea. When his dyspnea had become symptomatic, he had restarted his home dapsone prophylaxis, but his dyspnea had progressively worsened, and.

Recent Controversies in Pediatric Dermatology: The Usage of General Anesthesia in Young Children
https://www.mdedge.com/dermatology/article/143775/pediatrics/recent-controversies-pediatric-dermatology-usage-general
Nanette B. Silverberg, MD, Riva R. Ko, MD

Aug 2nd, 2017 - Clinicians who have attempted to perform an in-office procedure on infants or young children will recognize the difficulties that arise from the developmental inability to cooperate with procedures. 1 Potential problems mentioned in the literature.

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