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ALLMedicine™ Pernicious Anemia Center

Research & Reviews  158 results

Type I Polyglandular Autoimmune Syndrome
https://emedicine.medscape.com/article/124183-print

Nov 11th, 2021 - Practice Essentials Type I polyglandular autoimmune syndrome (PGA-I) is a rare disorder with sporadic autosomal recessive inheritance. The three major components of PGA-I are as follows: Chronic mucocutaneous candidiasis Hypoparathyroidism Autoimm...

Type I Polyglandular Autoimmune Syndrome
http://emedicine.medscape.com/article/124183-overview

Nov 11th, 2021 - Practice Essentials Type I polyglandular autoimmune syndrome (PGA-I) is a rare disorder with sporadic autosomal recessive inheritance. The three major components of PGA-I are as follows: Chronic mucocutaneous candidiasis Hypoparathyroidism Autoimm...

Perspective: The High-Folate-Low-Vitamin B-12 Interaction Is a Novel Cause of Vitamin B...
https://doi.org/10.1093/advances/nmab106
Advances in Nutrition (Bethesda, Md.); Selhub J, Miller JW et. al.

Oct 12th, 2021 - Vitamin B-12 is a water-soluble vitamin that plays important roles in intermediary metabolism. Vitamin B-12 deficiency has many identifiable causes, including autoimmune and other gastrointestinal malabsorption disorders, dietary deficiency, and c...

Megaloblastic Anemia
https://emedicine.medscape.com/article/204066-overview

Jul 17th, 2021 - Practice Essentials Megaloblasts are large nucleated red blood cells. (See the image below.) Vitamin B12 deficiency (eg, pernicious anemia), folic acid deficiency, and certain medications are the most common causes of megaloblastic anemia, a macro...

Genome-wide association study identifies five risk loci for pernicious anemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213695
Nature Communications; Laisk T, Lepamets M et. al.

Jun 20th, 2021 - Pernicious anemia is a rare condition characterized by vitamin B12 deficiency anemia due to lack of intrinsic factor, often caused by autoimmune gastritis. Patients with pernicious anemia have a higher incidence of other autoimmune disorders, such...

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Drugs  73 results see all →

Clinicaltrials.gov  2 results

Megadose of Hydroxocobalamin for the Treatment of Pernicious Anemia
https://clinicaltrials.gov/ct2/show/NCT03372447

Mar 8th, 2021 - The investigators will administrate a single intramuscular dose of hydroxocobalamin 10,000mcg, Thiamin 100mg, Pyridoxine 50mg. To assess response to treatment, a complete blood count (CBC) will be performed weekly during the first month of treatme...

Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy
https://clinicaltrials.gov/ct2/show/NCT00699478

Jul 19th, 2012 - Vitamin B 12 is important for hexane synthesis. Its deficiency causes pernicious anemia and abnormal functioning neurons. It is not synthesized intrinsically, and extrinsic supplement is vital. Vitamin B 12 is known to be abundant in meat and dair...

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News  24 results

Treating Vitamin B12 Deficiency: What Formulation Is Best?
https://www.medscape.com/viewarticle/926301_2

Mar 9th, 2020 - Oral B12: A Cheap, Effective Choice The Schilling test measures cobalamin absorption by assessing increased urine radioactivity after an oral dose of radioactive cobalamin. It is not readily available in most countries , however, so a measure of s...

Persistent Pruritic Papules on the Buttocks
https://www.mdedge.com/dermatology/article/214187/autoimmune-diseases/persistent-pruritic-papules-buttocks
Emily Ileen Patton, DO, Jared E. Roberts, MD et. al.

Dec 12th, 2019 - The Diagnosis: Dermatitis Herpetiformis Dermatitis herpetiformis (DH), also known as Duhring disease, is a rare autoimmune disease. It is the cutaneous manifestation of gluten sensitivity with antibodies targeting epidermal transglutaminase.

A 64-Year-Old Man With Throat Swelling
https://reference.medscape.com/viewarticle/900203_3

Aug 8th, 2018 - Which of the following is the most likely diagnosis? Your Peers Chose: Pernicious anemia 0% C1-INH deficiency 0% Drug-induced angioedema 0% Hereditary angioedema 0% Discussion Angiotensin-converting enzyme (ACE)-induced angioedema is a well-recogn...

Vitamin and Mineral Supplements: Which Patients Will Benefit?
https://www.medscape.com/viewarticle/892051

Feb 5th, 2018 - Hello. I am Dr JoAnn Manson, professor of medicine at Harvard Medical School and Brigham and Women's Hospital in Boston, Massachusetts. I'd like to talk with you today about vitamin and mineral supplements. Is there a rational approach? Most of ou...

A 26-Year-Old Man With Abdominal Pain
https://reference.medscape.com/viewarticle/721158_5

Jul 17th, 2017 - The mere presence of a diverticulum does not justify its surgical removal. If the diverticula are large and found in an isolated, dilated, and hypertrophied segment, and if they are the cause of intestinal obstruction, hemorrhage, adhesions, perfo...

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Patient Education  3 results see all →