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About 702 results

ALLMedicine™ Myeloproliferative Disease Center

Research & Reviews  343 results

Genome-wide DNA methylation profiling is able to identify prefibrotic PMF cases at risk...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860011
Clinical Epigenetics; Lehmann U, Stark H et. al.

Feb 5th, 2021 - Patients suffering from the BCR-ABL1-negative myeloproliferative disease prefibrotic primary myelofibrosis (pre-PMF) have a certain risk for progression to myelofibrosis. Accurate risk estimation for this fibrotic progression is of prognostic impo...

Hypereosinophilic syndrome with multiorgan involvement: an interdisciplinary work-up.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868273
BMJ Case Reports; Looman KIM, Nuver ME et. al.

Feb 5th, 2021 - A previously healthy 40-year-old man was referred to our emergency department with pruritic skin lesions and dyspnoea. Laboratory investigation revealed hypereosinophilia. Further diagnostic work-up confirmed the diagnosis of idiopathic hypereosin...

Periodontal management in a primary polycythemia rubra vera patient: A case report.
https://doi.org/10.1111/scd.12537
Special Care in Dentistry : Official Publication of the A... Hassan FW, Mohd N

Oct 30th, 2020 - Polycythemia rubra vera (PRV) is a myeloproliferative disease, which is characterized by the proliferation of all three major hematopoietic groups (erythrocytes, leucocytes and platelets). This hematological condition presented with different clin...

Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to an uncom...
https://doi.org/10.3324/haematol.2020.250969
Haematologica Ong J, Lin JI et. al.

Jun 3rd, 2020 - Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to an uncommon homozygous MPL p.Y591D mutation.|2020|Ong J,Lin JI,Mitchell H,Morgan S,Perkins AC,|

Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
https://doi.org/10.1182/blood.2019003910
Blood He H, Xu P et. al.

Apr 18th, 2020 - Hematopoietic stem cell (HSC) aging correlates with an increasing risk of myeloproliferative disease and immunosenescence. In this study, we show that aging-related inflammation promotes HSC aging through tumor necrosis factor-α (TNF-α)→ERK→ETS1→i...

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Guidelines  2 results

NCCN Guidelines Insights: Myeloproliferative Neoplasms, Version 2.2018
http://www.jnccn.org/content/15/10/1193.full
Mesa, R.,et al

Sep 30th, 2017 - Myeloproliferative neoplasms (MPNs) are a group of heterogeneous disorders of the hematopoietic system that include myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET). PV and ET are characterized by significant thromboh.

Myeloproliferative Neoplasms, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology
http://www.jnccn.org/content/14/12/1572.full
Mesa, R.,et al

Nov 30th, 2016 - Myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET) are a group of heterogeneous disorders of the hematopoietic system collectively known as Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs). The diagn.

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Clinicaltrials.gov  353 results

Genome-wide DNA methylation profiling is able to identify prefibrotic PMF cases at risk...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860011
Clinical Epigenetics; Lehmann U, Stark H et. al.

Feb 5th, 2021 - Patients suffering from the BCR-ABL1-negative myeloproliferative disease prefibrotic primary myelofibrosis (pre-PMF) have a certain risk for progression to myelofibrosis. Accurate risk estimation for this fibrotic progression is of prognostic impo...

Hypereosinophilic syndrome with multiorgan involvement: an interdisciplinary work-up.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868273
BMJ Case Reports; Looman KIM, Nuver ME et. al.

Feb 5th, 2021 - A previously healthy 40-year-old man was referred to our emergency department with pruritic skin lesions and dyspnoea. Laboratory investigation revealed hypereosinophilia. Further diagnostic work-up confirmed the diagnosis of idiopathic hypereosin...

Periodontal management in a primary polycythemia rubra vera patient: A case report.
https://doi.org/10.1111/scd.12537
Special Care in Dentistry : Official Publication of the A... Hassan FW, Mohd N

Oct 30th, 2020 - Polycythemia rubra vera (PRV) is a myeloproliferative disease, which is characterized by the proliferation of all three major hematopoietic groups (erythrocytes, leucocytes and platelets). This hematological condition presented with different clin...

Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to an uncom...
https://doi.org/10.3324/haematol.2020.250969
Haematologica Ong J, Lin JI et. al.

Jun 3rd, 2020 - Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to an uncommon homozygous MPL p.Y591D mutation.|2020|Ong J,Lin JI,Mitchell H,Morgan S,Perkins AC,|

Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
https://doi.org/10.1182/blood.2019003910
Blood He H, Xu P et. al.

Apr 18th, 2020 - Hematopoietic stem cell (HSC) aging correlates with an increasing risk of myeloproliferative disease and immunosenescence. In this study, we show that aging-related inflammation promotes HSC aging through tumor necrosis factor-α (TNF-α)→ERK→ETS1→i...

see more →

News  4 results

Switch may increase supply of HSCs from cord blood
https://www.mdedge.com/hematology-oncology/article/187211/transplantation/switch-may-increase-supply-hscs-cord-blood
HT Staff

Jul 15th, 2016 - Cord blood donation Photo courtesy of NHS Researchers have discovered a genetic switch that could increase the supply of hematopoietic stem cells (HSCs) derived from cord blood, according to a paper published in Cell Stem Cell. However, experiment.

Nilotinib Still Trumps Imatinib in Chronic CML
https://www.medpagetoday.com/hematologyoncology/leukemia/28127

Aug 20th, 2011 - Action Points Note that chronic myeloid leukemia is a myeloproliferative disease characterized by a chromosomal translocation, which leads to production of the BCR–ABL oncoprotein, an active tyrosine kinase. Tyrosine kinase inhibitor (TKI) imatini...

A Simple, Rapid, and Sensitive Method for the Detection of the JAK2 V617F Mutation
https://www.medscape.com/viewarticle/558906_1

Abstract and Introduction Abstract The point mutation 1849 (GAET) V617F in the JAK2gene occurs at high frequency in several chronic myeloproliferative diseases. Although a number of V617F mutation detection methods have been described, few are rea...

A Simple, Rapid, and Sensitive Method for the Detection of the JAK2 V617F Mutation
https://www.medscape.com/viewarticle/558906

Abstract and Introduction Abstract The point mutation 1849 (GAET) V617F in the JAK2gene occurs at high frequency in several chronic myeloproliferative diseases. Although a number of V617F mutation detection methods have been described, few are rea...

see more →