ALLMedicine™ Blood Substitutes Center

Oct 16th, 2020 - Fluorine-19 (19F) magnetic resonance (MR) molecular imaging is a promising noninvasive and quantitative molecular imaging approach with intensive research due to the high sensitivity and low endogenous background signal of the 19F atom in vivo. Pe...

Nov 4th, 2019 - We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. We contrib...

Apr 3rd, 2019 - It is only in the last 20 years that many of the original ideas on artificial cells are being increasingly applied and extended by researchers around the world. Artificial cell has now evolved into nanomedicine, biotherapeutics, blood substitutes,...

Mar 29th, 2019 - Despite the exhaustive search for an acceptable substitute to erythrocyte transfusion, neither chemical-based products such as perfluorocarbons nor hemoglobin-based oxygen carriers have succeeded in providing a reasonable alternative to allogeneic...

Dec 10th, 2018 - Overview The attempt to develop a viable blood substitute spans more than 7 decades. These efforts have essentially focused on the ability of red blood cells to carry oxygen. Hence, most of the products that are in advanced-phase clinical trials a...

Oct 16th, 2020 - Fluorine-19 (19F) magnetic resonance (MR) molecular imaging is a promising noninvasive and quantitative molecular imaging approach with intensive research due to the high sensitivity and low endogenous background signal of the 19F atom in vivo. Pe...

Nov 4th, 2019 - We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. We contrib...

Apr 3rd, 2019 - It is only in the last 20 years that many of the original ideas on artificial cells are being increasingly applied and extended by researchers around the world. Artificial cell has now evolved into nanomedicine, biotherapeutics, blood substitutes,...

Mar 29th, 2019 - Despite the exhaustive search for an acceptable substitute to erythrocyte transfusion, neither chemical-based products such as perfluorocarbons nor hemoglobin-based oxygen carriers have succeeded in providing a reasonable alternative to allogeneic...

Dec 10th, 2018 - Overview The attempt to develop a viable blood substitute spans more than 7 decades. These efforts have essentially focused on the ability of red blood cells to carry oxygen. Hence, most of the products that are in advanced-phase clinical trials a...

Apr 28th, 2008 - Action Points Explain to interested patients that a meta-analysis found that hemoglobin-based blood substitutes increase serious risks without increasing clinical benefit. Point out that none of these products is FDA-approved. BETHESDA, Md., April...

Abstract and Introduction Abstract Objectives: We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. Methods: We provide a review of the notable products developed in both categories and includ...