ALLMedicine™ Transfusion Reactions Center

Nov 3rd, 2021 - The U (universal) antigen is part of the MNS blood group present at a frequency of nearly 100% in Caucasians and 98% of African Americans. The anti-U antibody is clinically significant and has been reported to cause hemolytic transfusion reactions...

Oct 26th, 2021 - Blood transfusions are generally safe but can carry considerable risks. This review summarizes the different types of transfusion reactions and ways to diagnose and manage them. Symptoms are often overlapping and nonspecific. When a reaction is su...

Oct 23rd, 2021 - The reported incidence of adverse reactions following Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) transfusion has generally been lower than expected based on the incidence of transfusion reactions that have been observed in studi...

Oct 13th, 2021 - In previous studies, researchers highlight that children have higher rates of transfusion reactions than adults. However, little is known about the pediatric populations that experience reactions, and there are no reports that consider appropriate...

Oct 12th, 2021 - Delayed haemolytic transfusion reaction (DHTR) is a potentially life-threatening complication of red blood cell (RBC) transfusions in sickle cell disease (SCD) and is classically induced by reactivation of previously formed antibodies. Improved an...

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

Sep 10th, 2021 - Sickle cell disease (SCD) is a multisystem disorder associated with episodes of acute clinical events and progressive organ damage. Episodic pain, triggered by micro-vasoocclusion induced by sickled red blood cells, is the most common acute compli...

Dec 30th, 2020 - This is a prospective, randomized, double-blind controlled trial to evaluate the efficacy of placebo versus chlorpheniramine for the prevention of allergic transfusion reactions.

Oct 19th, 2020 - Reducing perioperative blood loss is critically important in the treatment of multiply injured combat casualties, and major blood loss during complex spine trauma surgery is a significant concern. Similar to previous studies in dental, cardiac, an...

Jun 5th, 2020 - Specific objectives Show the efficacy and safety of fresh plasma in different doses in severe cases and in very severe cases. Assess whether fresh plasma can overcome negative prognostic factors in very severe ill patients with COVID-19 infection....

Dec 12th, 2019 - Leukocyte antibodies can cause febrile transfusion reactions, pulmonary reactions to granulocyte transfusions, and transfusion related acute lung injury (TRALI). Despite the fact that the role of leukocyte antibodies in these reactions was first d...

Dec 20th, 2020 - Aaron Gerds, MD, assistant professor of medicine in the Hematology and Medical Oncology Department at the Cleveland Clinic Taussig Cancer Institute, discusses the adverse event anemia in patients with myelofibrosis. Anemia is a really big issue i...

Dec 4th, 2020 - Aaron Gerds, MD Luspatercept has shown efficacy as a treatment of anemia in patients with myelofibrosis (MF), a disease that is associated with high rates of anemia, explained Aaron T. Gerds, MD, MS. While JAK inhibitors including ruxolitinib (Ja...

Nov 18th, 2020 - Key clinical point : Approximately half of transfusion-dependent MDS patients said they had not discussed ways to reduce the need for transfusions with their doctors and 74% said there were no alternatives to blood transfusions. Major finding : Am.

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...