ALLMedicine™ Transfusion Reactions Center

Jul 3rd, 2022 - Unmasking delayed hemolytic transfusion reactions in patients with sickle-cell disease: Challenges and opportunities for improvement.|2022|Covington ML,Cone-Sullivan JK,Andrzejewski C,Lu W,Thomasson RR,|

Jul 2nd, 2022 - Bombay phenotype, an exceptionally rare blood type in individuals outside of Southeast Asia, occurs in approximately 1 in 1,000,000 individuals in Europe. This blood phenotype is characterized by the absence of the H antigen on red blood cells (RB...

Jul 2nd, 2022 - Among transfusion-associated adverse reactions, allergic transfusion reactions (ATRs) and febrile non-hemolytic transfusion reactions (FNHTRs) have a particularly high incidence. However, details of their occurrence time and related clinical facto...

Jun 28th, 2022 - Over 90% of patients undergoing cranial vault remodeling for craniosynostosis receive blood transfusions to compensate for intraoperative blood loss. However, transfusions are not without risk and can lead to allergic and immune transfusion reacti...

Jun 28th, 2022 - There are no international standards or normalizations for diagnosing and treating complications from blood transfusions. We comprehensively compared the incidence of adverse blood transfusions in children and adults. Available literature on blood...

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

May 10th, 2022 - Paracentesis-induced circulatory disturbance (PICD) is a very common cause of mortality and morbidity in patients undergoing large-volume paracentesis. Albumin is commonly used in decompensated cirrhosis during large-volume paracentesis. However, ...

Apr 8th, 2022 - Iron deficiency anemia (IDA) is the most common hematologic disorder in the United States and worldwide. Patients with moderate to severe anemia often present to the acute care setting for initial assessment and evaluation; women with abnormal ute...

Mar 8th, 2022 - Reducing perioperative blood loss is critically important in the treatment of multiply injured combat casualties, and major blood loss during complex spine trauma surgery is a significant concern. Similar to previous studies in dental, cardiac, an...

Mar 3rd, 2022 - Problem to be addressed: In December 2019, the Wuhan Municipal Health Committee (Wuhan, China) identified an outbreak of viral pneumonia cases of unknown cause. Coronavirus RNA was quickly identified in some of these patients.This novel coronaviru...

Feb 17th, 2022 - Sickle cell disease is an inherited defect caused by a mutation in the Beta globin gene affecting red blood cells. Symptoms begin at 6 months of life and often lead to debilitating vaso-occlusive pain crises, acute insults to vital organ systems,c...

Apr 6th, 2022 - MANCHESTER — Over a fifth of reported blood transfusion reactions are in patients with sickle cell disease, over half of which involve the potentially life-threatening complication hyperhaemolysis, suggests a UK analysis. "Haemolytic transfusion r...

Apr 2nd, 2021 - Transcript:Bijal D. Shah, MD: Risk stratification in acute lymphoblastic leukemia (ALL) is absolutely the next most important thing we can do to improve outcomes. Now, risk stratification involves, I think, fundamentally two components. The first ...

Dec 5th, 2020 - Eric H. Kraut, MD Erythropoietin-stimulating agents (ESAs), once considered miracle drugs that enjoyed widespread use for cancer-related anemia, fell into disfavor in 2007, when evidence demonstrated that ESAs decreased survival and time to dise...

Nov 18th, 2020 - Key clinical point : Approximately half of transfusion-dependent MDS patients said they had not discussed ways to reduce the need for transfusions with their doctors and 74% said there were no alternatives to blood transfusions. Major finding : Am.

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...