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About 1,823 results

ALLMedicine™ Transfusion Reactions Center

Research & Reviews  479 results

Unmasking delayed hemolytic transfusion reactions in patients with sickle-cell disease:...
https://doi.org/10.1111/trf.16967
Transfusion Covington ML, Cone-Sullivan JK et. al.

Jul 3rd, 2022 - Unmasking delayed hemolytic transfusion reactions in patients with sickle-cell disease: Challenges and opportunities for improvement.|2022|Covington ML,Cone-Sullivan JK,Andrzejewski C,Lu W,Thomasson RR,|

Incidental Discovery of a Patient with the Bombay Phenotype.
https://doi.org/10.1093/labmed/lmac075
Laboratory Medicine; Jacobs JW, Horstman E et. al.

Jul 2nd, 2022 - Bombay phenotype, an exceptionally rare blood type in individuals outside of Southeast Asia, occurs in approximately 1 in 1,000,000 individuals in Europe. This blood phenotype is characterized by the absence of the H antigen on red blood cells (RB...

Analysis of Clinical Factors Associated with the Occurrence Time of AllergicTransfusion...
https://www.ncbi.nlm.nih.gov/pubmed/35777807
Annals of Clinical and Laboratory Science; Yanagisawa R, Yamanaka R et. al.

Jul 2nd, 2022 - Among transfusion-associated adverse reactions, allergic transfusion reactions (ATRs) and febrile non-hemolytic transfusion reactions (FNHTRs) have a particularly high incidence. However, details of their occurrence time and related clinical facto...

The Effects of Preoperative Administration of Erythropoietin in Pediatric Patients Unde...
https://doi.org/10.1097/SCS.0000000000008648
The Journal of Craniofacial Surgery; Chumble A, Brush P et. al.

Jun 28th, 2022 - Over 90% of patients undergoing cranial vault remodeling for craniosynostosis receive blood transfusions to compensate for intraoperative blood loss. However, transfusions are not without risk and can lead to allergic and immune transfusion reacti...

Comparison of transfusion reactions in children and adults: A systematic review and met...
https://doi.org/10.1002/pbc.29842
Pediatric Blood & Cancer; Wang Y, Sun W et. al.

Jun 28th, 2022 - There are no international standards or normalizations for diagnosing and treating complications from blood transfusions. We comprehensively compared the incidence of adverse blood transfusions in children and adults. Available literature on blood...

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Guidelines  2 results

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion sup...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988392
Blood Advances; Chou ST, Alsawas M et. al.

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Red blood cell specifications for patients with hemoglobinopathies: a systematic review...
https://doi.org/10.1111/trf.14611
Transfusion Compernolle V, Chou ST et. al.

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

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Drugs  170 results see all →

Clinicaltrials.gov  42 results

Midodrine Versus Albumin for Prevention of Paracentesis Induced Circulatory Disturbance
https://clinicaltrials.gov/ct2/show/NCT05240391

May 10th, 2022 - Paracentesis-induced circulatory disturbance (PICD) is a very common cause of mortality and morbidity in patients undergoing large-volume paracentesis. Albumin is commonly used in decompensated cirrhosis during large-volume paracentesis. However, ...

IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department
https://clinicaltrials.gov/ct2/show/NCT05304442

Apr 8th, 2022 - Iron deficiency anemia (IDA) is the most common hematologic disorder in the United States and worldwide. Patients with moderate to severe anemia often present to the acute care setting for initial assessment and evaluation; women with abnormal ute...

Tranexamic Acid to Reduce Blood Loss in Spine Trauma Surgery
https://clinicaltrials.gov/ct2/show/NCT02314988

Mar 8th, 2022 - Reducing perioperative blood loss is critically important in the treatment of multiply injured combat casualties, and major blood loss during complex spine trauma surgery is a significant concern. Similar to previous studies in dental, cardiac, an...

CONvalescent Plasma for Hospitalized Adults With COVID-19 Respiratory Illness (CONCOR-1)
https://clinicaltrials.gov/ct2/show/NCT04348656

Mar 3rd, 2022 - Problem to be addressed: In December 2019, the Wuhan Municipal Health Committee (Wuhan, China) identified an outbreak of viral pneumonia cases of unknown cause. Coronavirus RNA was quickly identified in some of these patients.This novel coronaviru...

Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)
https://clinicaltrials.gov/ct2/show/NCT01499888

Feb 17th, 2022 - Sickle cell disease is an inherited defect caused by a mutation in the Beta globin gene affecting red blood cells. Symptoms begin at 6 months of life and often lead to debilitating vaso-occlusive pain crises, acute insults to vital organ systems,c...

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News  35 results

Greater Care Needed Over Transfusions in Sickle Cell Disease
https://www.medscape.com/viewarticle/971657

Apr 6th, 2022 - MANCHESTER — Over a fifth of reported blood transfusion reactions are in patients with sickle cell disease, over half of which involve the potentially life-threatening complication hyperhaemolysis, suggests a UK analysis. "Haemolytic transfusion r...

Induction and Post-Induction Therapy for Adult ALL
https://www.onclive.com/view/induction-and-post-induction-therapy-for-adult-all

Apr 2nd, 2021 - Transcript:Bijal D. Shah, MD: Risk stratification in acute lymphoblastic leukemia (ALL) is absolutely the next most important thing we can do to improve outcomes. Now, risk stratification involves, I think, fundamentally two components. The first ...

Management of Cancer-Related Anemia in 2011
https://www.onclive.com/view/management-of-cancer-related-anemia-in-2011

Dec 5th, 2020 - Eric H. Kraut, MD Erythropoietin-stimulating agents (ESAs), once considered miracle drugs that enjoyed widespread use for cancer-related anemia, fell into disfavor in 2007, when evidence demonstrated that ESAs decreased survival and time to dise...

Most transfusion-dependent MDS patients report positive quality of life
https://www.mdedge.com/fedprac/article/232099/myelodysplastic-syndrome/most-transfusion-dependent-mds-patients-report

Nov 18th, 2020 - Key clinical point : Approximately half of transfusion-dependent MDS patients said they had not discussed ways to reduce the need for transfusions with their doctors and 74% said there were no alternatives to blood transfusions. Major finding : Am.

FDA OKs Emergency Use of Convalescent Plasma for Seriously Ill COVID-19 Patients
https://www.staging.medscape.com/viewarticle/927716

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...

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Patient Education  1 results see all →