ALLMedicine™ Antiretroviral Therapy Center

Jan 15th, 2022 - Recent patent losses for antiretroviral drugs (ARV) have led to the debate of cost-saving through the replacement of patented drugs with generic drugs. The split of recommended single-tablet regimens (STR) into their single substance partners is o...

Jan 15th, 2022 - Studies on HIV disclosure and adherence among children performed in Latin America are anecdotal. We aimed to assess the factors associated with HIV disclosure, adherence and viral suppression among Ecuadorian children and compare the psychological...

Jan 15th, 2022 - Perceived discrimination and medical mistrust are contributors to HIV inequities. The current study examined whether medical mistrust mediated the associations between perceived discrimination and adherence to antiretroviral therapy (ART) as well ...

Jan 14th, 2022 - There are no studies comparing the prognosis for mature T-cell lymphoma (TCL) in people with human immunodeficiency virus (PWH) to people without HIV (PWoH) and to AIDS-defining B-cell lymphomas (A-BCL) in the modern antiretroviral therapy (ART) e...

Jan 14th, 2022 - We report the association between pre-antiretroviral therapy (pre-ART) soluble vascular cell adhesion molecule-1 (sVCAM-1) levels and long-term mortality in HIV-infected West African adults participating in a trial of early ART in West Africa (Tem...

Oct 15th, 2020 - Data on the use of antiretroviral drugs, including new drugs and formulations, for the treatment and prevention of HIV infection continue to guide optimal practices. To evaluate new data and incorporate them into current recommendations for initia...

Sep 5th, 2020 - The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years. The 2019 Guidelines were extended with a new section focusing on drug-drug interactions and other prescribing issues in pe...

Jan 4th, 2019 - Life expectancy of people living with HIV (PLWH) is reaching similar length as in the general population. Accordingly, age-related comorbidities, including osteoporosis, are increasing. Fracture risk is higher and increases approximately 10 years ...

Aug 23rd, 2018 - This Committee Opinion is being revised to provide updated guidance on the management of pregnant women during pregnancy and delivery to prevent mother-to-child transmission of the human immunodeficiency virus (HIV). Prevention of transmission of ...

Aug 23rd, 2018 - Given the enormous advances in the prevention of perinatal transmission of human immunodeficiency virus (HIV), it is clear that early identification and treatment of all pregnant women with HIV is the best way to prevent neonatal infection and als...

Jan 13th, 2022 - This study will evaluate the safety, tolerability, pharmacokinetics, and antiviral activity of SAR441236, a tri-specific broadly neutralizing antibody against HIV. The study includes three arms. In Arm A, three cohorts of antiretroviral-treated, v...

Jan 13th, 2022 - Objective: In this Phase I, proof-of-concept study, we aim to determine whether an antiretroviral regimen approved to treat human immunodeficiency virus (HIV) infection would also suppress levels of Human Endogenous Retrovirus-K (HERV-K) found to ...

Jan 12th, 2022 - Background: Antiretroviral therapy (ART) has altered the natural history of HIV disease in children. Long-term survivors of pediatric HIV infection offer a tremendous opportunity to understand the effects of HIV and ART health outcomes. A thorough...

Jan 12th, 2022 - HIV infection is known to cause profound and irreversible dysfunction of both innate and adaptive arms of the immune system. However, there is mounting evidence that early and aggressive treatment with antiretroviral drugs can prevent loss of immu...

Jan 11th, 2022 - This study consists of 2 Parts. Part 1 is a dose escalation phase. This phase is open-label, single dose titration study in adult people living with HIV. There are 3 stages: a screening stage of up to 14 days; on study study treatment stage, where...

Dec 3rd, 2021 - Dr Anthony S. Fauci Decades before becoming the go-to authority in the US on the COVID-19 global pandemic, Anthony S. Fauci, MD, found himself witnessing the earliest perplexing cases of what would become another devastating global pandemic — HIV/...

Nov 30th, 2021 - In low- and middle-income countries, dolutegravir (Tivicay) uptake in women still trailed that in men months after a safety reaffirmation from the World Health Organization (WHO), a large study showed. By March 2020, cumulative incidence of uptake...

Nov 19th, 2021 - Takeaway People living with HIV (PLHIV) in the UK had an increased risk of developing multiple comorbid conditions. Why this matters The findings emphasise the importance of regular reviews for PLHIV to monitor the development of comorbidities in ...

Nov 16th, 2021 - NEW YORK (Reuters Health) - A young woman from Esperanza, Argentina, may be the first to clear HIV-1 naturally without stem cell transplantation, raising hopes that a "sterilizing cure" may be an "extremely rare but possible" outcome of HIV-1 infe...

Nov 12th, 2021 - Long-acting therapies headlined a year of continued drug development, both in the treatment and prevention of HIV. Meanwhile, CDC recommended a third dose of a COVID-19 mRNA vaccine for certain patients living with advanced or untreated HIV to boo...