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About 11,255 results

ALLMedicine™ Acinetobacter Center

Research & Reviews  5,441 results

Prevalence of Genes Encoding Aminoglycoside-Modifying Enzymes and armA among Acinetobac...
https://doi.org/10.2174/1871526521666210225113041
Infectious Disorders Drug Targets; ELsheredy A, Yousif Z et. al.

Feb 26th, 2021 - Acinetobacter baumannii (A.baumannii ) is a ubiquitous pathogen responsible for serious infections in hospitalized patients with a high propensity to develop resistance to antimicrobial agents. The study aimed to determine the antimicrobial resist...

Rescuing the Last-Line Polymyxins: Achievements and Challenges.
https://doi.org/10.1124/pharmrev.120.000020
Pharmacological Reviews; Nang SC, Azad MAK et. al.

Feb 25th, 2021 - Antibiotic resistance is a major global health challenge and, worryingly, several key Gram negative pathogens can become resistant to most currently available antibiotics. Polymyxins have been revived as a last-line therapeutic option for the trea...

Molecular characterization and antibiotic resistance of Acinetobacter baumannii in cere...
https://doi.org/10.1371/journal.pone.0247418
PloS One; Shi X, Wang H et. al.

Feb 22nd, 2021 - The increasing prevalence of carbapenem-resistant Acinetobacter baumannii (CRAB) caused nosocomial infections generate significant comorbidity and can cause death among patients. Current treatment options are limited. These infections pose great d...

Targeting Superoxide dismutase confers enhanced Reactive Oxygen Species mediated eradic...
https://doi.org/10.1128/AAC.02180-20
Antimicrobial Agents and Chemotherapy; Dubey V, Gupta R et. al.

Feb 17th, 2021 - Bacterial persisters represent non-inheritable drug tolerant population that are linked to recalcitrance of infections in healthcare settings. The rise of antibiotic resistance and depletion of new antibiotics in drug discovery pipeline has made t...

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Guidelines  5 results

Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985752
Antimicrobial Agents and Chemotherapy; Pogue JM, Jones RN et. al.

Nov 26th, 2019 - The polymyxins are important agents for carbapenem-resistant Gram-negative bacilli. The United States Committee on Antimicrobial Susceptibility Testing breakpoint recommendations for colistin and polymyxin B are that isolates of Pseudomonas aerugi...

International Consensus Guidelines for the Optimal Use of the Polymyxins
https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.2209

Feb 1st, 2019 - The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the 1950s and thus did not undergo contemporary drug development procedures. Their clinical use has recently resurged, assuming an important role as salvage thera...

Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinet...
http://www.who.int/infection-prevention/publications/guidelines-cre/en/
WHO

Oct 31st, 2017 - Health care-associated infections (HAI) are one of the most common adverse events in care delivery. A large proportion are caused by antibiotic resistant organisms.

Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
https://doi.org/10.1007/s00134-015-4079-4
Intensive Care Medicine; Garnacho-Montero J, Dimopoulos G et. al.

Oct 6th, 2015 - Acinetobacter baumannii constitutes a dreadful problem in many ICUs worldwide. The very limited therapeutic options available for these organisms are a matter of great concern. No specific guidelines exist addressing the prevention and management ...

Antimicrobial resistance in major pathogens of hospital-acquired pneumonia in Asian cou...
https://doi.org/10.1016/j.ajic.2007.10.020
American Journal of Infection Control; Lagamayo EN

May 27th, 2008 - Antimicrobial resistance is a worldwide problem. For patients with hospital-acquired or ventilator-associated pneumonia, resistant pathogens pose a significant challenge to successful treatment outcomes and to the cost-effective delivery of health...

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Drugs  107 results see all →

Clinicaltrials.gov  5,615 results

Prevalence of Genes Encoding Aminoglycoside-Modifying Enzymes and armA among Acinetobac...
https://doi.org/10.2174/1871526521666210225113041
Infectious Disorders Drug Targets; ELsheredy A, Yousif Z et. al.

Feb 26th, 2021 - Acinetobacter baumannii (A.baumannii ) is a ubiquitous pathogen responsible for serious infections in hospitalized patients with a high propensity to develop resistance to antimicrobial agents. The study aimed to determine the antimicrobial resist...

Rescuing the Last-Line Polymyxins: Achievements and Challenges.
https://doi.org/10.1124/pharmrev.120.000020
Pharmacological Reviews; Nang SC, Azad MAK et. al.

Feb 25th, 2021 - Antibiotic resistance is a major global health challenge and, worryingly, several key Gram negative pathogens can become resistant to most currently available antibiotics. Polymyxins have been revived as a last-line therapeutic option for the trea...

Molecular characterization and antibiotic resistance of Acinetobacter baumannii in cere...
https://doi.org/10.1371/journal.pone.0247418
PloS One; Shi X, Wang H et. al.

Feb 22nd, 2021 - The increasing prevalence of carbapenem-resistant Acinetobacter baumannii (CRAB) caused nosocomial infections generate significant comorbidity and can cause death among patients. Current treatment options are limited. These infections pose great d...

Targeting Superoxide dismutase confers enhanced Reactive Oxygen Species mediated eradic...
https://doi.org/10.1128/AAC.02180-20
Antimicrobial Agents and Chemotherapy; Dubey V, Gupta R et. al.

Feb 17th, 2021 - Bacterial persisters represent non-inheritable drug tolerant population that are linked to recalcitrance of infections in healthcare settings. The rise of antibiotic resistance and depletion of new antibiotics in drug discovery pipeline has made t...

see more →

News  87 results

International Consensus Guidelines for the Optimal Use of the Polymyxins
https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.2209

Feb 1st, 2019 - The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the 1950s and thus did not undergo contemporary drug development procedures. Their clinical use has recently resurged, assuming an important role as salvage thera...

New pediatric therapies show promise for influenza, multidrug-resistant pathogens
https://www.mdedge.com/pulmonary-health-hub/article/184556/infectious-diseases/new-pediatric-therapies-show-promise
Jeff Craven

Nov 14th, 2018 - ORLANDO – More therapies are becoming available for children for the treatment of influenza and multidrug-resistant infections such as Enterobacteriaceae and Acinetobacter, John S. Bradley, MD, said at the annual meeting of the American Academy of.

Original Study: Should Nitrofurantoin Be Used to Treat Alkaline Urinary Tract Infection?
https://www.mdedge.com/emergencymedicine/article/170013/renal-genitourinary/original-study-should-nitrofurantoin-be-used/page/0/1

Jul 11th, 2018 - Results Data were categorized into 16 different bacterial genera or species. Acinetobacter (n = 1), Kluyvera ascorbata (n = 2), and Stenotrophomonas maltophilia (n = 3) were underrepresented in the dataset and therefore were not included in the da.

WHO: Superbugs Are Immediate Threat (Reuters)
https://www.medpagetoday.com/infectiousdisease/infectioncontrol/63434

Feb 27th, 2017 - The World Health Organization said there is an urgent need for new antibiotics to fight 12 "priority pathogens," Reuters reported. Classified on a tri-level scale -- medium, high, or critical -- the agency said the bacteria are resistant to many o...

Stronger 'Superbugs,' and No New Drugs to Fight Them
https://www.medscape.com/viewarticle/873337

Dec 15th, 2016 - (Reuters) - For nearly two years, a killer stalked the patients of Providence Alaska Medical Center. It was a bacteria called Acinetobacter baumannii, a common cause of infections in hospitals. This one was different. After a rash of mild cases in...

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