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About 11,431 results

ALLMedicine™ Acinetobacter Center

Research & Reviews  5,529 results

A randomized, double-blind, placebo- and positive-controlled crossover study of the eff...
https://doi.org/10.1111/cts.12991
Clinical and Translational Science; O'Donnell J, Maloney K et. al.

May 2nd, 2021 - Durlobactam (formerly ETX2514) is a diazabicyclooctane β-lactamase inhibitor that inhibits class A, C, and D β-lactamases. Sulbactam combined with durlobactam has in vitro and in vivo activity against Acinetobacter baumannii including carbapenem- ...

Multidrug resistance pattern of Acinetobacter species isolated from clinical specimens ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084144
PloS One; Ayenew Z, Tigabu E et. al.

Apr 29th, 2021 - Acinetobacter species have been a leading cause of nosocomial infections, causing significant morbidity and mortality over the entire world including Ethiopia. The most important features of A. baumannii are its ability to persist in the hospital ...

Multidrug Resistance Efflux Pumps in Acinetobacter spp.: An Update.
https://doi.org/10.1128/AAC.00514-21
Antimicrobial Agents and Chemotherapy; Kornelsen V, Kumar A

Apr 27th, 2021 - Acinetobacter spp. have become of increased clinical importance as studies have shown the antimicrobial resistant potential of these species. Efflux pumps can lead to reduced susceptibility to a variety of antibiotics and are present in large numb...

Revisiting colistin susceptibility testing: Will adding calcium to Mueller-Hinton agar ...
https://doi.org/10.1016/j.cmi.2021.04.014
Clinical Microbiology and Infection : the Official Public... Matuschek E, Brolund A et. al.

Apr 26th, 2021 - To investigate if adding calcium to Mueller-Hinton agar for gradient MIC or disk diffusion tests could improve separation between colistin susceptible and resistant populations of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and...

Personalised randomised controlled trial designs-a new paradigm to define optimal treat...
https://doi.org/10.1016/S1473-3099(20)30791-X
The Lancet. Infectious Diseases; Walker AS, White IR et. al.

Apr 24th, 2021 - Antimicrobial resistance is impacting treatment decisions for, and patient outcomes from, bacterial infections worldwide, with particular threats from infections with carbapenem-resistant Enterobacteriaceae, Acinetobacter baumanii, or Pseudomonas ...

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Guidelines  5 results

Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985752
Antimicrobial Agents and Chemotherapy; Pogue JM, Jones RN et. al.

Nov 26th, 2019 - The polymyxins are important agents for carbapenem-resistant Gram-negative bacilli. The United States Committee on Antimicrobial Susceptibility Testing breakpoint recommendations for colistin and polymyxin B are that isolates of Pseudomonas aerugi...

International Consensus Guidelines for the Optimal Use of the Polymyxins
https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.2209

Feb 1st, 2019 - The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the 1950s and thus did not undergo contemporary drug development procedures. Their clinical use has recently resurged, assuming an important role as salvage thera...

Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinet...
http://www.who.int/infection-prevention/publications/guidelines-cre/en/
WHO

Oct 31st, 2017 - Health care-associated infections (HAI) are one of the most common adverse events in care delivery. A large proportion are caused by antibiotic resistant organisms.

Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
https://doi.org/10.1007/s00134-015-4079-4
Intensive Care Medicine; Garnacho-Montero J, Dimopoulos G et. al.

Oct 6th, 2015 - Acinetobacter baumannii constitutes a dreadful problem in many ICUs worldwide. The very limited therapeutic options available for these organisms are a matter of great concern. No specific guidelines exist addressing the prevention and management ...

Antimicrobial resistance in major pathogens of hospital-acquired pneumonia in Asian cou...
https://doi.org/10.1016/j.ajic.2007.10.020
American Journal of Infection Control; Lagamayo EN

May 27th, 2008 - Antimicrobial resistance is a worldwide problem. For patients with hospital-acquired or ventilator-associated pneumonia, resistant pathogens pose a significant challenge to successful treatment outcomes and to the cost-effective delivery of health...

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Drugs  107 results see all →

Clinicaltrials.gov  5,703 results

A randomized, double-blind, placebo- and positive-controlled crossover study of the eff...
https://doi.org/10.1111/cts.12991
Clinical and Translational Science; O'Donnell J, Maloney K et. al.

May 2nd, 2021 - Durlobactam (formerly ETX2514) is a diazabicyclooctane β-lactamase inhibitor that inhibits class A, C, and D β-lactamases. Sulbactam combined with durlobactam has in vitro and in vivo activity against Acinetobacter baumannii including carbapenem- ...

Multidrug resistance pattern of Acinetobacter species isolated from clinical specimens ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084144
PloS One; Ayenew Z, Tigabu E et. al.

Apr 29th, 2021 - Acinetobacter species have been a leading cause of nosocomial infections, causing significant morbidity and mortality over the entire world including Ethiopia. The most important features of A. baumannii are its ability to persist in the hospital ...

Multidrug Resistance Efflux Pumps in Acinetobacter spp.: An Update.
https://doi.org/10.1128/AAC.00514-21
Antimicrobial Agents and Chemotherapy; Kornelsen V, Kumar A

Apr 27th, 2021 - Acinetobacter spp. have become of increased clinical importance as studies have shown the antimicrobial resistant potential of these species. Efflux pumps can lead to reduced susceptibility to a variety of antibiotics and are present in large numb...

Revisiting colistin susceptibility testing: Will adding calcium to Mueller-Hinton agar ...
https://doi.org/10.1016/j.cmi.2021.04.014
Clinical Microbiology and Infection : the Official Public... Matuschek E, Brolund A et. al.

Apr 26th, 2021 - To investigate if adding calcium to Mueller-Hinton agar for gradient MIC or disk diffusion tests could improve separation between colistin susceptible and resistant populations of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and...

Personalised randomised controlled trial designs-a new paradigm to define optimal treat...
https://doi.org/10.1016/S1473-3099(20)30791-X
The Lancet. Infectious Diseases; Walker AS, White IR et. al.

Apr 24th, 2021 - Antimicrobial resistance is impacting treatment decisions for, and patient outcomes from, bacterial infections worldwide, with particular threats from infections with carbapenem-resistant Enterobacteriaceae, Acinetobacter baumanii, or Pseudomonas ...

see more →

News  87 results

International Consensus Guidelines for the Optimal Use of the Polymyxins
https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.2209

Feb 1st, 2019 - The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the 1950s and thus did not undergo contemporary drug development procedures. Their clinical use has recently resurged, assuming an important role as salvage thera...

New pediatric therapies show promise for influenza, multidrug-resistant pathogens
https://www.mdedge.com/pulmonary-health-hub/article/184556/infectious-diseases/new-pediatric-therapies-show-promise
Jeff Craven

Nov 14th, 2018 - ORLANDO – More therapies are becoming available for children for the treatment of influenza and multidrug-resistant infections such as Enterobacteriaceae and Acinetobacter, John S. Bradley, MD, said at the annual meeting of the American Academy of.

Original Study: Should Nitrofurantoin Be Used to Treat Alkaline Urinary Tract Infection?
https://www.mdedge.com/emergencymedicine/article/170013/renal-genitourinary/original-study-should-nitrofurantoin-be-used/page/0/1

Jul 11th, 2018 - Results Data were categorized into 16 different bacterial genera or species. Acinetobacter (n = 1), Kluyvera ascorbata (n = 2), and Stenotrophomonas maltophilia (n = 3) were underrepresented in the dataset and therefore were not included in the da.

WHO: Superbugs Are Immediate Threat (Reuters)
https://www.medpagetoday.com/infectiousdisease/infectioncontrol/63434

Feb 27th, 2017 - The World Health Organization said there is an urgent need for new antibiotics to fight 12 "priority pathogens," Reuters reported. Classified on a tri-level scale -- medium, high, or critical -- the agency said the bacteria are resistant to many o...

Stronger 'Superbugs,' and No New Drugs to Fight Them
https://www.medscape.com/viewarticle/873337

Dec 15th, 2016 - (Reuters) - For nearly two years, a killer stalked the patients of Providence Alaska Medical Center. It was a bacteria called Acinetobacter baumannii, a common cause of infections in hospitals. This one was different. After a rash of mild cases in...

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