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About 8,315 results

ALLMedicine™ Acinetobacter Center

Research & Reviews  2,705 results

A New Insight to Silver Sulfadiazine Antibacterial Dressings: Nanoparticle-Loaded Nanof...
https://doi.org/10.1208/s12249-022-02465-9
AAPS PharmSciTech; Mutlu-Ağardan NB, Tort S et. al.

Dec 1st, 2022 - The aim of this study was formulating a new-generation antibacterial dressing in a form of polymer-based hybrid nanofiber-nanoparticles, effective on Gram-negative and Gram-positive bacteria using silver sulfadiazine (SSD), an FDA-approved topical...

Metal retention and replacement in QueD2 protect queuosine-tRNA biosynthesis in metal-s...
https://doi.org/10.1073/pnas.2213630119
Proceedings of the National Academy of Sciences of the Un... Jordan MR, Gonzalez-Gutierrez G et. al.

Nov 29th, 2022 - In response to bacterial infection, the vertebrate host employs the metal-sequestering protein calprotectin (CP) to withhold essential transition metals, notably Zn(II), to inhibit bacterial growth. Previous studies of the impact of CP-imposed tra...

Acinetobacter baumannii among Patients Receiving Glucocorticoid Aerosol Therapy during ...
https://doi.org/10.3201/eid2812.220347
Emerging Infectious Diseases; Zhang W, Yin M et. al.

Nov 24th, 2022 - Acinetobacter baumannii is a nosocomial pathogen associated with severe illness and death. Glucocorticoid aerosol is a common inhalation therapy in patients receiving invasive mechanical ventilation. We conducted a prospective cohort study to anal...

Silver Carboxylate-Eluting Titanium-Dioxide Polydimethylsiloxane Coating Inhibits Multi...
https://doi.org/10.1089/sur.2022.279
Surgical Infections; Garcia DR, Vishwanath N et. al.

Nov 23rd, 2022 - Background: Vancomycin-resistant Enterococcus faecalis and multi-drug-resistant (MDR) Acinetobacter baumannii are rising contributors to spinal fusion and fracture-associated infections (FAI), respectively. These MDR bacteria can form protective b...

Successful treatment with tigecycline of severe pandrug-resistant Acinetobacter baumann...
https://doi.org/10.21037/apm-22-900
Annals of Palliative Medicine; Liu X, Zhou H et. al.

Nov 22nd, 2022 - Acinetobacter baumannii (A. baumannii) is one of the most common pathogens that cause hospital-acquired infections. In recent years, drug-resistant A. baumannii has become prevalent worldwide, and pandrug-resistant A. baumannii is increasingly bei...

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Guidelines  4 results

Diagnosis and management of infections caused by multidrug-resistant bacteria: guidelin...
https://doi.org/10.1016/j.ijantimicag.2022.106611
International Journal of Antimicrobial Agents; Tiseo G, Brigante G et. al.

Jun 14th, 2022 - Management of patients with infections caused by multidrug-resistant organisms is challenging and requires a multidisciplinary approach to achieve successful clinical outcomes. The aim of this paper is to provide recommendations for the diagnosis ...

Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985752
Antimicrobial Agents and Chemotherapy; Pogue JM, Jones RN et. al.

Nov 27th, 2019 - The polymyxins are important agents for carbapenem-resistant Gram-negative bacilli. The United States Committee on Antimicrobial Susceptibility Testing breakpoint recommendations for colistin and polymyxin B are that isolates of Pseudomonas aerugi...

Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
https://doi.org/10.1007/s00134-015-4079-4
Intensive Care Medicine; Garnacho-Montero J, Dimopoulos G et. al.

Oct 7th, 2015 - Acinetobacter baumannii constitutes a dreadful problem in many ICUs worldwide. The very limited therapeutic options available for these organisms are a matter of great concern. No specific guidelines exist addressing the prevention and management ...

Preventing catheter-associated urinary tract infections: An executive summary of the As...
https://doi.org/10.1016/j.ajic.2010.08.003
American Journal of Infection Control; Rebmann T, Greene LR

Sep 28th, 2010 - The Association for Professionals in Infection Control and Epidemiology (APIC) began publishing their series of Elimination Guides in 2007. Since then, 9 Elimination Guides have been developed that cover a range of important infection prevention i...

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Drugs  408 results see all →

Clinicaltrials.gov  71 results

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV
https://clinicaltrials.gov/ct2/show/NCT04380207

Oct 10th, 2022 - The Centers for Disease Control (CDC) has listed carbapenem-resistant Enterobacteriaceae and Acinetobacter as urgent threats and multidrug resistant Pseudomonas, and extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae as serious t...

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT04808414

Oct 10th, 2022 - The United States (US) Centers for Disease Control (CDC) have listed multidrug-resistant (MDR) Acinetobacter and MDR Pseudomonas aeruginosa as serious threats [CDC, 2019]. Consistent with the global nature of these resistant bacteria, the World He...

Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects
https://clinicaltrials.gov/ct2/show/NCT05072444

Oct 10th, 2022 - The Centers for Disease Control (CDC) has listed carbapenem-resistant Enterobacteriaceae and Acinetobacter as urgent threats and multidrug resistant Pseudomonas, and extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae as serious t...

Bacteriophage Therapy TP-102 in Diabetic Foot Ulcers
https://clinicaltrials.gov/ct2/show/NCT04803708

Oct 4th, 2022 - The primary objective of this study is to evaluate the safety of a topical bacteriophage cocktail in the treatment of non infected and infected diabetic foot ulcers with Pseudomonas aeruginosa, Staphylococcus aureus and/or Acinetobacter baumanni. ...

RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI
https://clinicaltrials.gov/ct2/show/NCT03869437

Jun 6th, 2022 - Infections with antibiotic resistant bacteria cause a significant burden of disease worldwide. Bloodstream infections may arise from a variety of sources, are commonly encountered in clinical practice, and are associated with significant morbidity...

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News  138 results

COVID Pandemic Led to Surge in Superbug Infections, EU Agency Says
https://www.medscape.com/viewarticle/984207

Nov 18th, 2022 - LONDON (Reuters) - Infections from some antibiotic-resistant pathogens known as superbugs have more than doubled in health care facilities in Europe, an EU agency said on Thursday, providing further evidence of the wider impact of the COVID-19 pan...

Limiting Antibiotic Overprescription in Pandemics: New Guidelines
https://www.medscape.com/viewarticle/981201

Sep 21st, 2022 - A statement by the Society for Healthcare Epidemiology of America (SHEA), published online on September 14 in Infection Control & Hospital Epidemiology, offers healthcare providers guidelines on how to prevent inappropriate antibiotic use in futur...

CDC: COVID-19 Pandemic Undid Years of Progress in Fight Against Antimicrobial Resistance
https://www.medscape.com/viewarticle/978163

Jul 28th, 2022 - The COVID-19 pandemic erased years of progress in combating antibacterial resistance in the United States, according to a special report from the US Centers for Disease Control and Prevention (CDC). Arjun Srinivasan, MD "It is frightening to see t...

CDC: Pandemic Spurred Deadly Antimicrobial-Resistant Infections
https://www.medpagetoday.com/hospitalbasedmedicine/infectioncontrol/99687

Jul 12th, 2022 - A new CDC report warned that progress against deadly antimicrobial-resistant infections reversed course during the first year of the COVID-19 pandemic. After years of steady declines, antimicrobial-resistant hospital-related deaths and infections ...

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