ALLMedicine™ Bacterial Sepsis Center

Dec 17th, 2021 - Early diagnosis, precise antimicrobial treatment and subsequent patient stratification can improve sepsis outcomes. Circulating biomarkers such as plasma microRNAs (miRNAs) have proven to be surrogates for diagnosis, severity and case management o...

Dec 11th, 2021 - Optimal duration of antibiotic therapy in Gram-negative bacterial (GNB) sepsis in non-VLBW infants has not been specifically evaluated in previous studies. This was an open labeled noninferiority randomized controlled trial. Non-VLBW infants with ...

Nov 25th, 2021 - Aims: Recent in vitro findings suggest that the serine protease Granzyme K (GzmK) may act as a proinflammatory mediator. However, its role in sepsis is unknown. Here we aim to understand the role of GzmK in a mouse model of bacterial sepsis and co...

Nov 24th, 2021 - Severe combined immunodeficiency (SCID) consists of a group of disorders defined by abnormal B and T cell development that typically results in death within the first year of life if undiagnosed or untreated. Reticular dysgenesis (RD) is a rare bu...

Nov 9th, 2021 - In late 2019, a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of COVID-19 (COronaVIrus Disease-2019) in Hubei Province, China. COVID-19 has become a pandemic with approximately 4.1 ...

Nov 9th, 2021 - In late 2019, a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of COVID-19 (COronaVIrus Disease-2019) in Hubei Province, China. COVID-19 has become a pandemic with approximately 4.1 ...

Sep 28th, 2021 - Bacterial sepsis occurs in patients with severe infections. The condition is caused by toxic substances (toxins) released from bacteria and the patient's elevated inflammatory response to those toxins. In preclinical studies, human mesenchymal str...

Sep 9th, 2020 - Detailed objectives of the study are: To compare the efficacy of an optimised vancomycin dosing regimen to a standard vancomycin dosing regimen in patients with late onset, bacterial sepsis, known or suspected to be caused by Gram-positive microor...

Jun 1st, 2020 - In December 2019, severe pneumonia cases were reported in relation to the Huanan Seafood Wholesale Market in Wuhan, China. Four months and more than thousand deaths later, the responsible pathogen of the largest and most critical global health eme...

Aug 1st, 2018 - The delayed administration of an adequate antimicrobial therapy is a strong predictor of impaired outcome in patients with bacterial sepsis. Therefore, the current Surviving Sepsis Campaign guidelines (2016) recommend that administration of intrav...

Dec 20th, 2020 - Momelotinib improved overall survival (OS) and sustained efficacy outcomes in patients with intermediate- or high-risk myelofibrosis, according to updated findings from the phase 3 SIMPLIFY-1 and SIMPLIFY-2 trials.1,2 Lead author Srdan Verstovsek...

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Apr 15th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The SARS-CoV-2 novel coronavirus has dramatically altered specialty practice across the board, including the practice of infertility treatment. Reproductive medi...

Sep 9th, 2019 - A 55-year-old woman with type 2 diabetes and recently diagnosed ulcerative colitis is admitted to hospital with confusion and anxiety. She appears pale, and feels feverish. She notes that she is having heart palpitations and is short of breath. Vi...