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About 2,958 results

ALLMedicine™ Burkholderia Center

Research & Reviews  1,119 results

Precise measurement of the fitness effects of spontaneous mutations by droplet digital ...
https://doi.org/10.1093/genetics/iyab117
Genetics Rana A, Patton D et. al.

Dec 2nd, 2021 - Understanding how mutations affect survivability is a key component to knowing how organisms and complex traits evolve. However, most mutations have a minor effect on fitness and these effects are difficult to resolve using traditional molecular t...

Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound's...
https://doi.org/10.1080/22221751.2021.2011621
Emerging Microbes & Infections; Ku JWK, Marsh ST et. al.

Nov 26th, 2021 - Melioidosis is a serious infectious disease endemic in Southeast Asia, Northern Australia and has been increasingly reported in other tropical and subtropical regions in the world. Percutaneous inoculation through cuts and wounds on the skin is on...

Subclinical Burkholderia pseudomallei Infection Associated with Travel to the British V...
https://doi.org/10.3201/eid2712.211816
Emerging Infectious Diseases; Dewart CM, Almeida FA et. al.

Nov 23rd, 2021 - Phylogenetic analysis of a clinical isolate associated with subclinical Burkholderia pseudomallei infection revealed probable exposure in the British Virgin Islands, where reported infections are limited. Clinicians should consider this geographic...

In Vitro Susceptibility of Gram-negative Pathogens to Cefiderocol in Five Consecutive A...
https://doi.org/10.1128/AAC.01990-21
Antimicrobial Agents and Chemotherapy; Karlowsky JA, Hackel MA et. al.

Nov 23rd, 2021 - We report in vitro susceptibility data from five consecutive annual SIDERO-WT surveillance studies (2014-2019) for cefiderocol and comparators tested against Gram-negative clinical isolates from North America and Europe. CLSI broth microdilution w...

Increased Incidence of Melioidosis in Far North Queensland, Queensland, Australia, 1998...
https://doi.org/10.3201/eid2712.211302
Emerging Infectious Diseases; Smith S, Horne P et. al.

Nov 23rd, 2021 - During January 1998-December 2019, the annual incidence of melioidosis in Far North Queensland, Queensland, Australia, more than doubled. Because climate and prevalence of predisposing medical conditions remained stable during that time, we hypoth...

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Drugs  21 results see all →

Clinicaltrials.gov  6 results

Inhaled Gaseous Nitric Oxide (gNO) Antimicrobial Treatment of Difficult Bacterial and Viral Lung (COVID-19) Infections
https://clinicaltrials.gov/ct2/show/NCT03331445

Jul 16th, 2021 - Main Study Primary Objective: Assess the safety of inhaled NO (gNO) in adults & adolescents with NTM, Burkholderia, Aspergillus Lung Infections and Viral Lung (COVID-19) Infections Safety will be evaluated by unanticipated adverse events in clinic...

Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis
https://clinicaltrials.gov/ct2/show/NCT02694393

Mar 5th, 2021 - Pseudomonas aeruginosa infects the airways of 80% of adults with Cystic Fibrosis (CF). In these patients, P. aeruginosa forms extremely antibiotic resistant biofilm communities that accelerate progression of obstructive lung disease. Current treat...

Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia
https://clinicaltrials.gov/ct2/show/NCT01966796

Sep 9th, 2020 - MDR bacteria were defined as Pseudomonas aeruginosa (P. aeruginosa), Enterobacter species, those not sensitive to second and third generation cephalosporins, Acinetobacter species, extended-spectrum β-lactamase (ESBL) Enterobacteriaceae such as Es...

Diagnostic Accuracy of the DPP II Assay
https://clinicaltrials.gov/ct2/show/NCT04299412

Apr 3rd, 2020 - Burkholderia pseudomallei is responsible for melioidosis, a disease that can present a range of signs and symptoms and can be treated by a specific drug regimen. Diagnosis of melioidosis is made by isolation of the bacteria from body fluids or tis...

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis and Chronic Burkholderia Species Infection
https://clinicaltrials.gov/ct2/show/NCT01059565

Mar 11th, 2014 - The purpose of this research study was to determine if an experimental drug called Aztreonam for Inhalation Solution (AZLI) was safe and effective to treat Burkholderia lung infections in patients with cystic fibrosis (CF). Spirometry was used to ...

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News  37 results

FDA Warns Clinicians to Stop Using Eco-Med Products Because of Contamination Concerns
https://www.medscape.com/viewarticle/956871

Aug 18th, 2021 - The US Food and Drug Administration (FDA) is urging healthcare providers to immediately stop use of and discard all Eco-Med ultrasound gels and lotions because of risk for bacterial contamination with Burkholderia cepacia complex (Bcc).  In early ...

CDC Reports Burkholderia cepacia and B pseudomallei Outbreaks
https://www.medscape.com/viewarticle/956548

Aug 12th, 2021 - The CDC and FDA have announced an outbreak of at least 15 Burkholderia cepacia infections associated with contaminated ultrasound gel used to guide invasive procedures as well as an unrelated outbreak of Burkholderia pseudomallei that caused two d...

Case Series Shows Feasibility of Haploidentical Transplant in High-Risk Myelofibrosis
https://www.onclive.com/view/case-series-shows-feasibility-of-haploidentical-transplant-in-highrisk-myelofibrosis

Dec 4th, 2020 - Keri Maher, DO, MS Haploidentical allogeneic stem cell transplant is a viable treatment option for patients with myelofibrosis who have a higher risk for posttransplant complications and mortality, according to a 3-patient case series shared in a...

Anti-Migraine Drug Recalled Due to Potential Contamination
https://www.medscape.com/viewarticle/917018

Aug 19th, 2019 - Pfizer is recalling two lots of eletriptan hydrobromide (Relpax) 40-mg tablets because of potential contamination with Pseudomonas and Burkholderia bacteria, the company has announced. The drug is indicated for the acute treatment of migraine with...

Nurse Assist Inc. Recalls Normal Saline Flush IV Syringes Due to Possible Burkholderia Cepacia Bloodstream Infections | FDA
https://www.fda.gov/medical-devices/medical-device-recalls/nurse-assist-inc-recalls-normal-saline-flush-iv-syringes-due-possible-burkholderia-cepacia

The FDA has identified this as a Class I recall, the most serious type of recall. Use of these devices may cause serious injuries or death. Recalled Product: Product Name: Normal Saline Flush Product Description: 12 mL IV Flush Syringe with a 3 mL...

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