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About 3,310 results

ALLMedicine™ Burkholderia Center

Research & Reviews  1,235 results

Progressive dysbiosis of human orodigestive microbiota along the sequence of gastroesop...
https://doi.org/10.1002/ijc.34191
International Journal of Cancer; Hao Y, Karaoz U et. al.

Jun 26th, 2022 - The incidence of esophageal adenocarcinoma (EA) has drastically increased in the United States since 1970s for unclear reasons. We hypothesized that the widespread usage of antibiotics has increased the procarcinogenic potential of the orodigestiv...

Melioidosis: an unusual diagnosis for deep temporal and masticatory space infection fol...
https://doi.org/10.1136/bcr-2022-248866
BMJ Case Reports; Shetty NS, Karikal A et. al.

Jun 23rd, 2022 - We report a patient in his early 70s, with an alleged history of trauma to the right temporal region, following which a swelling developed. A week later, erythematous changes, throbbing pain and occasional fever spikes were noted. A month after th...

The AraC/XylS Protein MxiE and Its Coregulator IpgC Control a Negative Feedback Loop in...
https://doi.org/10.1128/jb.00137-22
Journal of Bacteriology; McKenna JA, Karney MMA et. al.

Jun 16th, 2022 - Members of the AraC family of transcriptional regulators (AFTRs) control the expression of many genes important to cellular processes, including virulence. In Shigella species, the type III secretion system (T3SS), a key determinant for host cell ...

A rare case of melioidosis presenting as myositis in Sri Lanka.
https://doi.org/10.1186/s12879-022-07515-y 10.1186/s13256-019-2321-3 10.1371/journal.pntd.0000900 10.1177/1535370215583801 10.3390/tropicalmed3010022 10.1128/CMR.18.2.383-416.2005 10.1086/509810 10.31128/AJGP-04-18-4558 10.1016/S0140-6736(03)13374-0
BMC Infectious Diseases; Vithana SMP, Chathuranga LS et. al.

Jun 16th, 2022 - Melioidosis caused by Burkholderia pseudomallei is an emerging infection in Sri Lanka with a high case fatality rate. The disease usually manifests as pneumonia, however multisystem involvement is common. Myositis is an extremely rare occurrence a...

Clinical Burkholderia pseudomallei isolates from north Queensland carry diverse bimABm ...
https://doi.org/10.1371/journal.pntd.0009482
PLoS Neglected Tropical Diseases; Burnard D, Bauer MJ et. al.

Jun 15th, 2022 - Burkholderia pseudomallei is an environmental gram-negative bacterium that causes the disease melioidosis and is endemic in many countries of the Asia-Pacific region. In Australia, the mortality rate remains high at approximately 10%, despite cura...

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Drugs  23 results see all →

Clinicaltrials.gov  19 results

RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI
https://clinicaltrials.gov/ct2/show/NCT03869437

Jun 6th, 2022 - Infections with antibiotic resistant bacteria cause a significant burden of disease worldwide. Bloodstream infections may arise from a variety of sources, are commonly encountered in clinical practice, and are associated with significant morbidity...

Pharmacokinetics of Omadacycline in Cystic Fibrosis
https://clinicaltrials.gov/ct2/show/NCT04460586

Sep 24th, 2021 - Omadacycline exhibits excellent activity against bacteria including methicillin-resistant Staphylococcus aureus (MRSA), Burkholderia cepacia, and Nontuberculous mycobacteria (NTM) that are a potential source of lung infection in CF patients. As om...

A Single-blind Stepped Wedge Cluster Randomized Controlled Behaviour Change Trial to Determine Effectiveness of Prevention Programme of Melioidosis in Diabetics in Ubon Ratchathani, Northeast Thail...
https://clinicaltrials.gov/ct2/show/NCT02089152

Jul 21st, 2021 - Melioidosis is an infectious disease caused by soil-dwelling Gram-negative bacilli Burkholderia pseudomallei. The disease is highly endemic in northeast Thailand. Diabetes mellitus is the major underlying risk factor for melioidosis, occurring in ...

Inhaled Gaseous Nitric Oxide (gNO) Antimicrobial Treatment of Difficult Bacterial and Viral Lung (COVID-19) Infections
https://clinicaltrials.gov/ct2/show/NCT03331445

Jul 16th, 2021 - Main Study Primary Objective: Assess the safety of inhaled NO (gNO) in adults & adolescents with NTM, Burkholderia, Aspergillus Lung Infections and Viral Lung (COVID-19) Infections Safety will be evaluated by unanticipated adverse events in clinic...

Parenting Concerns in Patients With Cystic Fibrosis (MucoPar)
https://clinicaltrials.gov/ct2/show/NCT04133246

Apr 19th, 2021 - Life expectancy has improved significantly in cystic fibrosis in recent years. From paediatric disease, it has become a disease of the adult, with the emergence of new issues, such as becoming a parent. Parent patients still face the risk of compl...

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News  47 results

CDC Details Deadly Aromatherapy Outbreak
https://www.medpagetoday.com/primarycare/generalprimarycare/97467

Mar 2nd, 2022 - While the lavender-scented spritz from Walmart might have seemed the furthest thing from exotic, the Burkholderia pseudomallei bacteria inside sparked a deadly melioidosis outbreak that CDC scientists highlighted as a reason to watch for unexpecte...

Can Phages Help Where Antibiotics Have Failed?
https://www.medscape.com/viewarticle/969001

Feb 23rd, 2022 - A new film called Salt in My Soul was recently released, with one of the expressed goals being to raise funds for phage research and antibiotic resistance. Mallory Smith The film shares the story of Mallory Smith, a young woman, now deceased, who ...

Freshwater Aquarium Provides Source for Melioidosis Infection
https://www.medscape.com/viewarticle/965928

Jan 3rd, 2022 - A Maryland woman came down with a severe tropical infection called melioidosis from her freshwater home aquarium, says a report in the journal Emerging Infectious Diseases describing a new route of transmission. Melioidosis is caused by the bacter...

FDA Warns Clinicians to Stop Using Eco-Med Products Because of Contamination Concerns
https://www.medscape.com/viewarticle/956871

Aug 18th, 2021 - The US Food and Drug Administration (FDA) is urging healthcare providers to immediately stop use of and discard all Eco-Med ultrasound gels and lotions because of risk for bacterial contamination with Burkholderia cepacia complex (Bcc).  In early ...

CDC Reports Burkholderia cepacia and B pseudomallei Outbreaks
https://www.medscape.com/viewarticle/956548

Aug 12th, 2021 - The CDC and FDA have announced an outbreak of at least 15 Burkholderia cepacia infections associated with contaminated ultrasound gel used to guide invasive procedures as well as an unrelated outbreak of Burkholderia pseudomallei that caused two d...

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