ALLMedicine™ Infective Endocarditis Center

Jun 28th, 2022 - Prosthetic valve endocarditis with mechanical complications causing pulmonary edema is fatal, therefore it needs to be diagnosed early and should be treated surgically in emergency setting. Transesophageal echocardiogram is crucial for recognizing...

Jun 26th, 2022 - This report describes a patient with destructive multivalvular endocarditis with multiorgan dysfunction. Intraoperatively severe unexpected adhesions due to pancarditis precluded the standard commando operation. The approach of combining autotrans...

Jun 25th, 2022 - Effective prevention of thromboembolism is essential for patients with mechanical prosthetic heart valves. For this group of patients, vitamin K antagonists (VKAs) remain the drug group of choice despite the widespread use of new anticoagulants in...

Jun 24th, 2022 - Transesophageal echocardiography (TEE) is the gold standard for the detection of valvular vegetations (VV). Differentiating small VV from degenerative changes is challenging and prone to inter-observer variability. We evaluated inter-observer agre...

Jun 24th, 2022 - Staphylococcus aureus is a medically important pathogen with high metabolic versatility allowing it to infect various niches within a host. S. aureus utilizes two major transcriptional regulators, namely, CodY and CcpA, to remodel metabolic and vi...

Oct 30th, 2021 - In 2007, the American Heart Association published updated evidence-based guidelines on the recommended use of antibiotic prophylaxis to prevent viridans group streptococcal (VGS) infective endocarditis (IE) in cardiac patients undergoing invasive ...

May 8th, 2021 - Infective endocarditis can involve a normal, abnormal, or prosthetic cardiac valve. The diagnosis is typically made clinically with persistently positive blood cultures, characteristic signs and symptoms, and echocardiographic evidence of valvular...

Apr 4th, 2017 - 2016 The American Association for Thoracic Surgery (AATS) consensus guidelines: Surgical treatment of infective endocarditis: Executive summary.|2017| ,Pettersson GB,Coselli JS, ,Pettersson GB,|therapeutic use,standards,diagnosis,etiology,surgery,...

Sep 17th, 2015 - Infective Endocarditis in Childhood: 2015 Update: A Scientific Statement From the American Heart Association.|2015|Baltimore RS,Gewitz M,Baddour LM,Beerman LB,Jackson MA,|physiology,blood,therapeutic use,complications,microbiology,diagnosis,microb...

Sep 17th, 2015 - Infective endocarditis is a potentially lethal disease that has undergone major changes in both host and pathogen. The epidemiology of infective endocarditis has become more complex with today's myriad healthcare-associated factors that predispose...

Jun 21st, 2022 - The purpose of this superiority study is to evaluate the efficacy and safety of exebacase in addition to standard of care antibiotics (SoCA) compared with SoCA alone for the treatment of patients with Staphylococcus aureus (S. aureus) bloodstream ...

Jun 7th, 2022 - All the clinical, biological, microbiological and laboratory describing the history of patients and their evolution during hospitalization for infective endocarditis will be obtained from physicians supporting patients and recorded in an electroni...

Jun 3rd, 2022 - This is a Phase 2b clinical study, multicenter, randomized, open-label, assessor-blinded, superiority study. The study will compare dalbavancin to standard of care antibiotic therapy for the completion of therapy in patients with complicated bacte...

Jun 1st, 2022 - The trial will include patients diagnosed with left-side Infective Endocarditis according to the modified Duke criteria, with ≥10 days of appropriate parenteral antibiotic treatment overall and at least one week of appropriate parenteral treatment...

May 12th, 2022 - This study evaluates safety and tolerability of endolysin-derived LSVT-1701 (tonabacase) as an add-on to standard of care (SOC) antibiotic therapy for the treatment of patients with complicated Staphylococcus aureus bacteremia (SAB), including lef...

Mar 16th, 2022 - Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways Survival of patients with type 2 diabetes deteriorates after more than 3 years following heart valve surger...

Sep 28th, 2021 - In response to a study published in August, FDA is investigating whether women really have worse outcomes after Watchman left atrial appendage occlusion (LAAO) than men. Shorter intervals between measurements: a way to slice a minute off standard ...

May 6th, 2021 - Patients who suffer a stroke during hospitalization for infective endocarditis (IE) after transcatheter aortic valve replacement (TAVR) have a dismal prognosis, with more than half dying during the index hospitalization and two thirds within the f...

Apr 27th, 2021 - One consequence of the ongoing opioid epidemic in the United States may be an increase in the number of hemorrhagic strokes caused by infective endocarditis, research suggests. Intravenous drug use (IVDU) can cause this bacterial infection of the ...

Apr 1st, 2021 - The occurrence of endocarditis in hemodialysis patients may be significantly higher than previously thought, but it is as lethal as ever, a new observational study suggests. Researchers examined data from patients with infective endocarditis from ...