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About 4,683 results

ALLMedicine™ Aspergillosis Center

Research & Reviews  1,629 results

Case Commentary: Long-term fosmanogepix use in a transplant recipient with disseminated...
https://doi.org/10.1128/aac.02368-21
Antimicrobial Agents and Chemotherapy; Kline A, Lionakis MS

Jan 25th, 2022 - Aspergillus calidoustus is an emerging, azole-resistant, cryptic Aspergillus species in immunosuppressed patients that often features extrapulmonary involvement and carries high mortality. The case presented by J. F. Camargo, R. Jabr, A. D. Anders...

Outcomes of surgery for different types of chronic pulmonary aspergillosis: results fro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772183
BMC Pulmonary Medicine; Shen C, Qiao G et. al.

Jan 21st, 2022 - The reported experience of surgical treatment for chronic pulmonary aspergillosis (CPA) mainly focused on simple aspergilloma (SA), few about other types of CPA. The present study aims to evaluate the outcomes of surgical treatment for different t...

Impact of emphysema on the prognosis of Mycobacterium avium complex pulmonary disease.
https://doi.org/10.1016/j.rmed.2022.106738
Respiratory Medicine; Takasaka N, Hosaka Y et. al.

Jan 21st, 2022 - Chronic obstructive pulmonary disease (COPD) is a major comorbid disease of Mycobacterium avium complex pulmonary disease (MAC-PD). Emphysema is one of the main pathological findings in COPD, a risk factor for chronic pulmonary aspergillosis (CPA)...

Fungal Sinusitis
http://emedicine.medscape.com/article/863062-overview

Jan 19th, 2022 - Practice Essentials Fungal infections of the sinuses have recently been blamed for causing most cases of chronic rhinosinusitis. The evidence, though, is still controversial. Most fungal sinus infections are benign or noninvasive, except when they...

Fungal Sinusitis
https://emedicine.medscape.com/article/863062-print

Jan 19th, 2022 - Practice Essentials Fungal infections of the sinuses have recently been blamed for causing most cases of chronic rhinosinusitis. The evidence, though, is still controversial. Most fungal sinus infections are benign or noninvasive, except when they...

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Guidelines  7 results

Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727169
American Journal of Respiratory and Critical Care Medicine; Hage CA, Carmona EM et. al.

Aug 31st, 2019 - Background: Fungal infections are of increasing incidence and importance in immunocompromised and immunocompetent patients. Timely diagnosis relies on appropriate use of laboratory testing in susceptible patients.Methods: The relevant literature r...

ESCMID-ECMM guideline: diagnosis and management of invasive aspergillosis in neonates a...
https://doi.org/10.1016/j.cmi.2019.05.019
Clinical Microbiology and Infection : the Official Public... Warris A, Lehrnbecher T et. al.

Jun 4th, 2019 - Presenting symptoms, distributions and patterns of diseases and vulnerability to invasive aspergillosis (IA) are similar between children and adults. However, differences exist in the epidemiology and underlying conditions, the usefulness of newer...

Individualized Medication of Voriconazole: A Practice Guideline of the Division of Ther...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250289
Therapeutic Drug Monitoring; Chen K, Zhang X et. al.

Sep 8th, 2018 - Voriconazole (VRZ) is a second-generation triazole antifungal agent with broad-spectrum activity. It is available in both intravenous and oral formulations, and is primarily indicated for treating invasive aspergillosis. The most commonly used dos...

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-...
https://doi.org/10.1016/j.cmi.2018.01.002
Clinical Microbiology and Infection : the Official Public... Ullmann AJ, Aguado JM et. al.

Mar 17th, 2018 - The European Society for Clinical Microbiology and Infectious Diseases, the European Confederation of Medical Mycology and the European Respiratory Society Joint Clinical Guidelines focus on diagnosis and management of aspergillosis. Of the numero...

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormyc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394968
Haematologica Tissot F, Agrawal S et. al.

Dec 25th, 2016 - The European Conference on Infections in Leukemia (ECIL) provides recommendations for diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various types of infection in patients with hematologic malignancies or he...

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Drugs  92 results see all →

Clinicaltrials.gov  64 results

Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)
https://clinicaltrials.gov/ct2/show/NCT04218851

Dec 2nd, 2021 - This study will evaluate the safety, efficacy, and pharmacokinetics of posaconazole (POS) intravenous (IV) and oral formulations in pediatric participants 2 to <18 years of age with invasive aspergillosis (IA).

PC945 Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients
https://clinicaltrials.gov/ct2/show/NCT05037851

Nov 30th, 2021 - Part 1 of the study comprises a 12 week Prophylaxis or Pre-emptive Therapy Phase. Part 2 comprises a 4-week Safety Follow-Up Phase. The study will screen single or double lung transplant recipients due to receive a mold-active antifungal: either a...

Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA
https://clinicaltrials.gov/ct2/show/NCT03920527

Oct 12th, 2021 - Aspergillus is a saprophytic fungus which is present normally in our surroundings and causes a large number of pulmonary diseases spreading through inhalational route. The spectrum of disease caused by aspergillus spp. is wide with the manifestati...

Pharmacological Evaluation of Antifungal in Chronic Pulmonary Aspergillosis
https://clinicaltrials.gov/ct2/show/NCT05064605

Oct 1st, 2021 - Knowledge of these elements is however an essential prerequisite for optimizing the dosages in these contexts. The main objective of the study is to quantify the diffusion of antifungals in the lower respiratory tract in patients treated for pulmo...

Prospective Clinical Evaluation of Beta-D-Glucan Assay in Blood and BAL
https://clinicaltrials.gov/ct2/show/NCT01576653

Sep 28th, 2021 - In patients with invasive fungal infection (IFI) rapid diagnosis is essential for early initiation of appropriate antifungal therapy and thereby survival. Conventional culture is still the Gold-Standard for diagnosis of IFI. Sensitivity of convent...

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News  78 results

GM-EIA and BDG assays ineffective for IFD diagnosis in AML patients receiving antifungal prophylaxis
https://www.mdedge.com/hematology-oncology/article/243646/aml/gm-eia-and-bdg-assays-ineffective-ifd-diagnosis-aml-patients

Jul 30th, 2021 - Key clinical point: Twice-weekly surveillance with galactomannan enzyme immunoassay (GM-EIA) and b-D-glucan (BDG) assay was ineffective at detecting invasive fungal diseases (IFDs) in children, adolescents, and young adults with acute myeloid leuk.

Five Things You Need to Know About Bronchiectasis
https://www.medscape.com/viewarticle/955069

Jul 22nd, 2021 - Bronchiectasis is a chronic condition characterised by symptoms of persistent or recurrent bronchial sepsis caused by irreversible damage to and dilation of the bronchi.[1] The key principles of the diagnosis and management of bronchiectasis were ...

Diagnostic tests may miss invasive aspergillosis in children
http://www.mdedge.com/infectiousdisease/article/239319/invasive-fungal-infections/diagnostic-tests-may-miss-invasive

Apr 28th, 2021 - Key clinical point : The small number of invasive aspergillosis cases may contribute to the low specificity of several tests in children after stem cell transplants and should be interpreted with caution. Major finding: The sensitivity and specifi.

Multiple sclerosis patients may develop fungal infections on disease-modifying drugs
https://www.mdedge.com/infectiousdisease/article/239312/invasive-fungal-infections/multiple-sclerosis-patients-may-develop

Apr 28th, 2021 - Key clinical point : Invasive fungal infections, though rare, have been observed in multiple sclerosis patients using a range of disease-modifying treatments and should be suspected in patients presenting with signs of infection. Major finding : T.

RADIANT-3 Trial: Everolimus for Patients With pNETs
https://www.onclive.com/view/radiant-3-trial-everolimus-for-patients-with-pnets

Apr 2nd, 2021 - For High-Definition, Click The utilization of the mTOR inhibitor everolimus as a treatment for patients with pancreatic neuroendocrine tumors (pNET) has increased since the FDA first approved the drug in this space in 2011, based on findings fro...

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Patient Education  3 results see all →