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About 2,305 results

ALLMedicine™ Alcoholic Hepatitis Center

Research & Reviews  692 results

Increased Prevalence of Alcohol-Related Gastrointestinal and Liver Diseases During the ...
https://www.ncbi.nlm.nih.gov/pubmed/36413455
Rhode Island Medical Journal (2013); Kothadia S, Chung W et. al.

Nov 23rd, 2022 - Higher prevalence of alcohol-related gastrointestinal (GI) and liver diseases (ARGLDs) were anecdotally reported during the COVID-19 pandemic, but little published evidence exists. A healthcare system audit of inpatient GI consults was performed d...

Effect of an Integrated Transplantation Mental Health Program on Alcohol Relapse After ...
https://doi.org/10.1016/j.transproceed.2022.09.026
Transplantation Proceedings; Zanowski SC, Price JS et. al.

Nov 22nd, 2022 - Liver transplantation (LT) for severe alcohol-associated hepatitis (AH) remains controversial due to perceived increased recidivism risk after LT because of a lack of protracted abstinence before LT. Data on risk stratification for alcohol relapse...

The Liverpool alcohol-related liver disease algorithm identifies twice as many emergenc...
https://doi.org/10.1111/apt.17307
Alimentary Pharmacology & Therapeutics; Dhanda A, Bodger K et. al.

Nov 19th, 2022 - Emergency admissions in England for alcohol-related liver disease (ArLD) have increased steadily for decades. Statistics based on administrative data typically focus on the ArLD-specific code as the primary diagnosis and are therefore at risk of e...

The Mechanisms of Systemic Inflammatory and Immunosuppressive Acute-on-Chronic Liver Fa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646330
Journal of Immunology Research; Kou K, Sun X et. al.

Nov 18th, 2022 - Acute-on-chronic liver failure (ACLF) is a complex clinical syndrome, and patients often have high short-term mortality. It occurs with intense systemic inflammation, often accompanied by a proinflammatory event (such as infection or alcoholic hep...

Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced s...
https://doi.org/10.1016/j.metabol.2022.155334
Metabolism: Clinical and Experimental; Dong H, Zhong W et. al.

Nov 10th, 2022 - Alcohol consumption has been shown to disrupt hepatic lipid homeostasis. Long-chain acyl-CoA synthetase 1 (ACSL1) critically regulates hepatic fatty acid metabolism and lipid homeostasis by channeling fatty acids to lipid metabolic pathways. Howev...

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Guidelines  3 results

ACG Clinical Guideline: Alcoholic Liver Disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524956
The American Journal of Gastroenterology; Singal AK, Bataller R et. al.

Jan 18th, 2018 - Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at advanced stages and data on the prevalence and profile of ...

Medical Management of Severe Alcoholic Hepatitis: Expert Review from the Clinical Practice Updates Committee of the AGA Institute
https://www.cghjournal.org/article/S1542-3565(16)30798-4/fulltext?code=yjcgh-site

Apr 17th, 2017 - The purpose of this clinical practice update is to review diagnostic criteria for severe acute alcoholic hepatitis and to determine the current best practices for this life-threatening condition. The best practices in this review are based on clin...

Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alco...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287362
Gastroenterology Crabb DW, Bataller R et. al.

Feb 28th, 2016 - Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia.|2016|Crabb DW,Bataller R,Chalasani NP,Kamath PS,Lucey M,|classification,standards,...

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Clinicaltrials.gov  114 results

A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment
https://clinicaltrials.gov/ct2/show/NCT04563026

Sep 30th, 2022 - This is a randomized, double-blind, placebo-controlled, phase 2b clinical Trial evaluating Safety and Efficacy of DUR-928 (an experimental medication) in Patients with Alcoholic Hepatitis (AH).

Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis
https://clinicaltrials.gov/ct2/show/NCT04072822

Sep 16th, 2022 - This multicenter, randomized, double blinded, placebo-controlled clinical trial is focused on novel treatments for severe alcoholic hepatitis (AH), a life-threatening stage of alcoholic liver injury that has a short-term mortality rate much higher...

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH
https://clinicaltrials.gov/ct2/show/NCT03845205

Sep 9th, 2022 - In the United States, alcoholic liver disease (ALD) is the second most common indication for liver transplant (LT). Traditionally, ALD patients have been required to complete a six-month mandatory period of alcohol abstinence before LT. More recen...

sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis
https://clinicaltrials.gov/ct2/show/NCT02924701

Aug 12th, 2022 - Primary biliary cholangitis (PBC, previously called 'primary biliary cirrhosis') is an autoimmune cholestatic liver disease characterized by destruction of intrahepatic bile ducts and progression to liver fibrosis and cirrhosis. In the pre-cirrhot...

Efficacy and Safety of G-CSF in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid
https://clinicaltrials.gov/ct2/show/NCT02442180

Aug 8th, 2022 - Severe alcoholic hepatitis is defined as alcoholic hepatitis patients having discriminant function (DF) score over 32 or accompanying hepatic encephalopathy. These patients have shown poor prognosis of 28 day mortality as 30 to 50% without treatme...

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News  105 results

Steroids and G-CSF Improve 90-day Survival in Severe Alcoholic Hepatitis
https://www.medscape.com/viewarticle/983798

Nov 9th, 2022 - WASHINGTON — Adding granulocyte-colony stimulating factor (G-CSF) to steroid therapy can improve 90-day survival for patients with severe alcoholic hepatitis (SAH), researchers from India reported. Among patients with SAH, the combination of G-CSF...

Past Decompensation in Alcoholic Hepatitis Not 'Absolute Contraindication' to Early Transplant
https://www.medscape.com/viewarticle/978309

Jul 29th, 2022 - Past decompensation in alcohol-associated hepatitis may be linked with worse survival following liver transplantation, but it's not all bad news, according to a retrospective study. Traditionally, patients with alcoholic liver disease were asked t...

Alcohol-related Liver Disease Clinical Practice Guidelines (AFEF, 2022)
https://www.medscape.com/viewarticle/974654

Jun 1st, 2022 - Guidelines for the management of alcohol-related liver disease were published in April 2022 by the French Association for the Study of the Liver (AFEF) in Liver International.[1] Use the AUDIT-C questionnaire in general practice and specialist con...

Treatment for Alcohol Abuse Reduces Hepatitis Readmission
https://www.medscape.com/viewarticle/974503

May 24th, 2022 - SAN DIEGO — Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.83% of those patients who received psychotherapy, counsel...

Treatment for alcohol abuse reduces hepatitis readmission
https://www.mdedge.com/internalmedicine/article/254812/hepatology/treatment-alcohol-abuse-reduces-hepatitis-readmission
Laird Harrison

May 22nd, 2022 - SAN DIEGO – Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.

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Patient Education  8 results see all →