ALLMedicine™ Cholangitis Center

Jun 27th, 2022 - PDC-E2 specific CD8+ T cells play a leading role in biliary destruction in PBC. However, there are limited data on characterization of these autoantigen specific CD8+ T cells, particularly in liver. Here we aimed to identify the pathogenic intrahe...

Jun 27th, 2022 - The association between ulcerative colitis (UC) and primary sclerosing cholangitis has been described for several years and can be classified as having a distinct disease phenotype from inflammatory bowel diseases (IBD). The simultaneous occurrenc...

Jun 25th, 2022 - Cholestatic liver injury triggers a wound healing response orchestrated by Kupffer cells (KCs), hepatic stellate cells (HSCs) and other immune cells that leads to peribiliary fibrosis and disease progression. Inflammation is central, particularly ...

Jun 24th, 2022 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

Jun 24th, 2022 - Background: Metastatic digestive tract cancers, in particular esophageal, gastric, pancreatic and hepatobiliary carcinomas, are associated with poor survival beyond five years and poor response to existing therapies. Data from the National Cancer ...

Jun 24th, 2022 - EASL Clinical Practice Guidelines on Sclerosing Cholangitis.|2022| , ,|

Aug 1st, 2021 - Primary biliary cholangitis (PBC) is a chronic inflammatory disease of the intra-hepatic bile ducts [1]. It is characterised biologically by chronic cholestasis associated with the presence of specific autoantibodies, and histologically by lesions...

Aug 1st, 2021 - Primary sclerosing cholangitis (PSC) is a rare and chronic cholestatic liver disease of unknown cause commonly associated with inflammatory bowel disease (IBD) and characterized by progressive obliterative fibro-inflammation of the biliary tree. A...

May 24th, 2021 - Cholangitis is a GI emergency requiring prompt recognition and treatment. The purpose of this document from the American Society for Gastrointestinal Endoscopy's (ASGE) Standards of Practice Committee is to provide an evidence-based approach for m...

Oct 22nd, 2020 - Endoscopy is an essential component in the management of inflammatory bowel disease [IBD]. There is a risk of SARS-CoV-2 transmission during endoscopic procedures. The International Organization for the study of IBD [IOIBD] has developed 11 positi...

Jun 24th, 2022 - Background: Metastatic digestive tract cancers, in particular esophageal, gastric, pancreatic and hepatobiliary carcinomas, are associated with poor survival beyond five years and poor response to existing therapies. Data from the National Cancer ...

Jun 24th, 2022 - In this single-site, small-scale prospective natural history study, we intend to recruit up to 40 patients with PSC diagnosed by standard clinical, biochemical, or imaging features (including up to 30 with a known diagnosis of IBD) and up to 90 co...

Jun 24th, 2022 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

Jun 21st, 2022 - This study will consist of a Screening Visit, a 7-day Run-in Period, a 16-week Treatment Period, and a Follow-up Visit (approximately 7-10 days after the last dose of study drug). Informed consent will be obtained prior to performing any study-spe...

Jun 15th, 2022 - AIMS A) Characterize unusual disease and pathologic presentations which require endoscopic treatment in a large safety net hospital B) To study the impact of EUS and ERCP on the management of these patients. C) Analyze how EUS and ERCP results cor...

May 27th, 2022 - Patients with acute cholangitis are twice as likely to be readmitted within 30 days if they don't get a cholecystectomy in the same hospital admission for which they get biliary decompression, researchers say. The readmissions result mostly from s...

Mar 1st, 2022 - Inflammatory bowel disease (IBD) patients diagnosed with colorectal cancer (CRC) had better cancer outcomes when they had undergone a recent surveillance colonoscopy, a retrospective study of military veterans found. In the analysis of over 550 su...

Feb 11th, 2022 - A case-control study revealed which patients were more likely to use herbal products for irritable bowel syndrome. (BMC Gastroenterology) Diabetes following a liver transplant was linked to cancer risk, a study from Italy found. (Annals of Hepatol...

Dec 10th, 2021 - NEW YORK (Reuters Health) - Immune-mediated diseases were associated with an increased risk of local and systemic cancers, as well as total cancers, in a large cohort study, supporting the role of local and systemic immunoregulation in the develop...

Sep 7th, 2021 - NEW YORK (Reuters Health) - About 2% of patients with inflammatory bowel diseases (IBD) will develop primary sclerosing cholangitis (PSC), with a higher prevalence in men than women, according to a new analysis. In a paper in Gastroenterology, the...