ALLMedicine™ Escherichia Coli Center

Jan 22nd, 2022 - Leafy green vegetables are a common source of Shiga toxin-producing Escherichia coli O157:H7 (STEC O157) foodborne illness outbreaks. Ruminant animals, primarily cattle, are the major reservoir of STEC O157. Epidemiological, traceback and field in...

Jan 21st, 2022 - In Canada, enteric infections cause significant health and economic burden. We evaluated the individual characteristics of laboratory-confirmed cases of Campylobacter spp. (n = 28,728), non-typhoidal Salmonella spp. (n = 22,640), Yersinia spp. (n ...

Jan 21st, 2022 - Inflammatory bowel disease (IBD) affects millions of people worldwide and has emerged as a growing problem in industrialized nations. The lack of therapeutic targets has limited the treatment of IBD. Studies found that parasitic nematode infection...

Jan 20th, 2022 - The use of efflux pump inhibitors (EPIs) as potentiators along with the traditional antibiotics assists in the warfare against antibiotic-resistant superbugs. Efflux pumps of the resistance-nodulation-cell division (RND) family play crucial roles ...

Jan 19th, 2022 - DEAD-box proteins (DBPs) are a prominent class of RNA remodeling proteins that alter RNA structure, a process they typically perform through an ATP-dependent RNA helicase activity. Although many DBPs have been characterized at the structural and f...

Dec 18th, 2013 - Sales of raw or unpasteurized milk and milk products are still legal in at least 30 states in the United States. Raw milk and milk products from cows, goats, and sheep continue to be a source of bacterial infections attributable to a number of vir...

Jul 6th, 2010 - Adequate detection of carbapenemase-producing Enterobacteriaceae is crucial for infection control measures and appropriate choice of antimicrobial therapy. This guideline aims to improve the detection of carbapenemase-producing Enterobacteriaceae ...

Oct 17th, 2009 - Shiga toxin--producing Escherichia coli (STEC) are a leading cause of bacterial enteric infections in the United States. Prompt, accurate diagnosis of STEC infection is important because appropriate treatment early in the course of infection might...

Sep 19th, 2008 - This guideline for the investigation and initial treatment of atypical hemolytic uremic syndrome (HUS) is intended to offer an approach based on opinion, as evidence is lacking. It builds on the current ability to identify the etiology of specific...

Jan 19th, 2022 - ExPEC10V (JNJ-69968054) is a 10-valent vaccine candidate in development for prevention of invasive extraintestinal pathogenic Escherichia coli (ExPEC) disease (IED) in adults 60 years of age and older. ExPEC10V consists of O-antigen polysaccharide...

Dec 10th, 2021 - Escherichia Coli poses a major public health problem. E. Coli is not only a commensal of the digestive tract but also a major opportunistic pathogen, first cause of urinary tract infections, first cause of bacteremia. However, little is known abou...

Sep 24th, 2021 - other data elements, such as eligibility criteria or outcome measures. (Limit: 32,000 characters) Project title: Pre-delivery administration of azithromycin to prevent neonatal sepsis and death: a phase III double-blind randomized clinical trial A...

Sep 21st, 2021 - Janssen Research & Development is developing ExPEC10V, a 10-valent conjugate vaccine comprising the 10 most predominant O-polysaccharides of ExPEC. Invasive ExPEC Disease (IED) is defined as an acute illness consistent with bacterial infection tha...

Aug 24th, 2021 - The purpose of this study is to determine if EcoActive is safe and effective in people with Crohn's disease. EcoActive is a collection of bacteriophages. Bacteriophages (or phages) are viruses that infect only bacteria. The phages in EcoActive inf...

Nov 4th, 2021 - In this question-and-answer article (the first in a series), our objective is to reinforce for the clinician several practical points of management for common infectious diseases. The principal references for the answers to the questions are 2 tex.

Oct 11th, 2021 - NEW YORK (Reuters Health) - Cord-blood-derived products marketed for treatments that the U.S. Food and Drug Administration (FDA) has not approved may be contaminated with bacteria, a new government study shows. In an investigation of bacterial inf...

Aug 3rd, 2021 - Bristol Myers Squibb (BMS) has made the decision to withdraw in the indication for romidepsin (Istodax) as a monotherapy for the treatment of adult patients with peripheral T-cell lymphoma (PTCL) who have previously received at least 1 therapy.1 ...

Jul 2nd, 2021 - The US Food and Drug Administration (FDA) has approved a new version of asparaginase for use in children and adults who have developed hypersensitivity to asparaginase derived from Escherichia coli. The new product is Jazz Pharmaceutical's Rylaze ...

Jun 24th, 2021 - Key clinical point: Fungal or bacterial bloodstream infections were common in children within 5 years of liver or kidney transplants; the overall incidence in the first year post-transplant was 1. 91 per 100 recipients per month.