ALLMedicine™ Early HIV Infection Center

Mar 29th, 2022 - Specific Aims: Recent studies suggest that very early initiation of ART (prior to seroconversion) does not prevent the establishment of HIV reservoirs, which eventually expand when ART is discontinued. Early ART initiation is, however, associated ...

Mar 17th, 2022 - Although antiretroviral therapy (ART) has prolonged the lives of HIV-infected individuals, HIV reservoir remains the main stumbling block to HIV cure. Presently, early ART initiation is one of the effective measures to reduce the HIV reservoir. Th...

Dec 1st, 2021 - Initiation of combination antiretroviral therapy (cART) during acute or early HIV-infection (AEHI) limits the size of the viral reservoir and preserves immune function. This renders individuals who started cART during AEHI promising participants i...

Nov 12th, 2021 - In 2019, the US Government announced its goal to end the HIV epidemic within 10 years, mirroring the initiatives set forth by UNAIDS. Public health prevention interventions are a crucial part of this ambitious goal. However, numerous challenges to...

Nov 1st, 2021 - Limited access to HIV treatment is a major problem in many parts of the world. If a well tolerated anti-HIV regimen with convenient once-daily dosing is effective in reducing viral load in people with recent or early HIV infection, this regimen co...

Mar 29th, 2022 - Specific Aims: Recent studies suggest that very early initiation of ART (prior to seroconversion) does not prevent the establishment of HIV reservoirs, which eventually expand when ART is discontinued. Early ART initiation is, however, associated ...

Nov 1st, 2021 - Limited access to HIV treatment is a major problem in many parts of the world. If a well tolerated anti-HIV regimen with convenient once-daily dosing is effective in reducing viral load in people with recent or early HIV infection, this regimen co...

Nov 1st, 2021 - Combination antiretroviral therapy including two nucleoside reverse transcriptase inhibitors (NRTIs) and a single HIV-1 protease inhibitor (PI) results in significant and sustained decreases in plasma HIV-1 RNA with a resultant marked diminution i...

Oct 29th, 2021 - In this prospective longitudinal study we aim to assess how immunologic and viral aspects of the human immunodeficiency virus (HIV) viral reservoir, established during early HIV infection and responsible for viral rebound at treatment interruption...

Oct 28th, 2021 - There is increasing data on the potential for inhibition of immune activation as primary therapy for HIV infection. The rationale of CsA therapy is to decrease T cell activation in patients with early HIV infection. Activation of T cells leads to ...

Apr 29th, 2015 - Hello. This is Dr Paul Sax from Brigham and Women's Hospital and Harvard Medical School. Today I'd like to discuss the recently updated Department of Health and Human Services (DHHS) HIV treatment guidelines,[1] which were released on April 8. In ...

Jun 21st, 2013 - Action Points New approaches to HIV testing can detect acute infections that would have gone undetected with older methods. Note that new 4th-generation tests detect both immunoglobulin M-class and G-class antibodies as well as the p24 antigen whe...

Nov 11th, 2009 - November 11, 2009 — A review published in the November 1 issue of American Family Physician describes the role of primary care clinicians in the treatment of patients with HIV infection. "Prevention and treatment of...HIV infection have changed co...

Aug 5th, 2008 - Action Points Explain to interested patients that the study suggested lower-than-expected accuracy of the rapid oral HIV test. Inform patients that the rapid test appeared to identify patients at elevated risk for HIV infection. BOSTON, Aug. 5 -- ...

Feb 25th, 2005 - Action Points Advise concerned patients that this is an isolated case and that others like it have not been reported but that this is another reason to practice safe sex. At the same time, remind patients who engage in risky sexual practices to ge...