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About 2,645 results

ALLMedicine™ African Trypanosomiasis Center

Research & Reviews  1,319 results

Modelling to quantify the likelihood that local elimination of transmission has occurre...
https://doi.org/10.1093/cid/ciab190
Clinical Infectious Diseases : an Official Publication Of... Davis CN, Castaño MS et. al.

Apr 27th, 2021 - The gambiense human African trypanosomiasis (gHAT) elimination programme in the Democratic Republic of Congo (DRC) routinely collects case data through passive surveillance and active screening, with several regions reporting no cases for several ...

Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Stud...
https://doi.org/10.1021/acsinfecdis.1c00048
ACS Infectious Diseases; Martín-Escolano R, Etxebeste-Mitxeltorena M et. al.

Apr 19th, 2021 - Chagas disease is a tropical infection caused by the protozoan parasite Trypanosoma cruzi and a global public health concern. It is a paradigmatic example of a chronic disease without an effective treatment. Current treatments targeting T. cruzi a...

Early Stages of Drug Discovery in an Academic Institution and Involvement of Pharma for...
https://doi.org/10.1021/acsinfecdis.1c00091
ACS Infectious Diseases; Gelb MH, Buckner FS

Apr 19th, 2021 - In this Viewpoint, we provide a brief description of two efforts to develop drugs to treat diseases caused by tropical parasites (Malaria, human African trypanosomiasis and Chagas disease). These efforts are largely based in a University setting b...

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078842
PLoS Neglected Tropical Diseases; Sanderson L, da Silva M et. al.

Apr 15th, 2021 - Human African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system stage whe...

Cost-effectiveness modelling to optimise active screening strategy for gambiense human ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017623
BMC Medicine; Davis CN, Rock KS et. al.

Apr 2nd, 2021 - Gambiense human African trypanosomiasis (gHAT) has been brought under control recently with village-based active screening playing a major role in case reduction. In the approach to elimination, we investigate how to optimise active screening in v...

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Clinicaltrials.gov  1,323 results

Modelling to quantify the likelihood that local elimination of transmission has occurre...
https://doi.org/10.1093/cid/ciab190
Clinical Infectious Diseases : an Official Publication Of... Davis CN, Castaño MS et. al.

Apr 27th, 2021 - The gambiense human African trypanosomiasis (gHAT) elimination programme in the Democratic Republic of Congo (DRC) routinely collects case data through passive surveillance and active screening, with several regions reporting no cases for several ...

Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Stud...
https://doi.org/10.1021/acsinfecdis.1c00048
ACS Infectious Diseases; Martín-Escolano R, Etxebeste-Mitxeltorena M et. al.

Apr 19th, 2021 - Chagas disease is a tropical infection caused by the protozoan parasite Trypanosoma cruzi and a global public health concern. It is a paradigmatic example of a chronic disease without an effective treatment. Current treatments targeting T. cruzi a...

Early Stages of Drug Discovery in an Academic Institution and Involvement of Pharma for...
https://doi.org/10.1021/acsinfecdis.1c00091
ACS Infectious Diseases; Gelb MH, Buckner FS

Apr 19th, 2021 - In this Viewpoint, we provide a brief description of two efforts to develop drugs to treat diseases caused by tropical parasites (Malaria, human African trypanosomiasis and Chagas disease). These efforts are largely based in a University setting b...

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078842
PLoS Neglected Tropical Diseases; Sanderson L, da Silva M et. al.

Apr 15th, 2021 - Human African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system stage whe...

Cost-effectiveness modelling to optimise active screening strategy for gambiense human ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017623
BMC Medicine; Davis CN, Rock KS et. al.

Apr 2nd, 2021 - Gambiense human African trypanosomiasis (gHAT) has been brought under control recently with village-based active screening playing a major role in case reduction. In the approach to elimination, we investigate how to optimise active screening in v...

see more →

News  3 results

What Neglected Tropical Diseases Teach Us About Stigma
https://www.mdedge.com/dermatology/article/209336/infectious-diseases/what-neglected-tropical-diseases-teach-us-about?channel=234
Aileen Y. Chang, MD, Maria T. Ochoa, MD

Oct 3rd, 2019 - Neglected tropical diseases (NTDs) are a group of 20 diseases that typically are chronic and cause long-term disability, which negatively impacts work productivity, child survival, and school performance and attendance with adverse effect on futur.

EMA Panel Backs First Oral-Only Drug for Deadly Sleeping Sickness
https://www.medscape.com/viewarticle/905009

Nov 15th, 2018 - The first oral-only treatment for human African trypanosomiasis (HAT), commonly known as sleeping sickness, has received a green light from the Committee for Human Medicinal Products (CHMP) of the European Medicines Agency (EMA). Fexinidazole Wint...

Advising Patients on Safe Travel Abroad
https://www.medscape.com/viewarticle/741804_3

May 5th, 2011 - Specific Recommendations Arthropod-Borne Diseases Arthropods are not only a source of nuisance and pain at the site of their bites, but they also may cause more harmful generalized reactions as a result of venom production or allergies to substanc...

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