About 1,148 results

ALLMedicine™ African Trypanosomiasis Center

Research & Reviews  453 results

Passive surveillance of human African trypanosomiasis in Côte d'Ivoire: Understanding p...
PLoS Neglected Tropical Diseases; Koné M, Kaba D et. al.

Aug 31st, 2021 - Little is known about the diagnostic performance of rapid diagnostic tests (RDTs) for passive screening of human African trypanosomiasis (HAT) in Côte d'Ivoire. We determined HAT prevalence among clinical suspects, identified clinical symptoms and...

Estimating the impact of Tiny Targets in reducing the incidence of Gambian sleeping sic...
Parasites & Vectors; Bessell PR, Esterhuizen J et. al.

Aug 20th, 2021 - Riverine species of tsetse (Glossina) transmit Trypanosoma brucei gambiense, which causes Gambian human African trypanosomiasis (gHAT), a neglected tropical disease. Uganda aims to eliminate gHAT as a public health problem through detection and tr...

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents.
International Journal for Parasitology. Drugs and Drug Re... Lin C, Hulpia F et. al.

Aug 11th, 2021 - Kinetoplastid parasites are the causative agents of Chagas disease (CD), leishmaniasis and human African trypanosomiasis (HAT). Despite a sustained decrease in the number of HAT cases, more efforts are needed to discover safe and effective therapi...

Multiplex Bead Assay for the Detection of Human IgG Antibody Responses to African Trypa...
The American Journal of Tropical Medicine and Hygiene; Priest JW, Handali S

Aug 10th, 2021 - The recent introduction of large-scale, population-based serologic surveys in several nations where human African trypanosomiasis (HAT) remains endemic could provide an opportunity to better map the remaining disease foci and to identify asymptoma...

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in d...
PLoS Pathogens; Steketee PC, Dickie EA et. al.

Jul 27th, 2021 - Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense. In comparison to the well-studied T. brucei, there is a major pau...

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Drugs  1 results see all →

News  5 results

What Neglected Tropical Diseases Teach Us About Stigma
Aileen Y. Chang, MD, Maria T. Ochoa, MD

Oct 3rd, 2019 - Neglected tropical diseases (NTDs) are a group of 20 diseases that typically are chronic and cause long-term disability, which negatively impacts work productivity, child survival, and school performance and attendance with adverse effect on futur.

EMA Panel Backs First Oral-Only Drug for Deadly Sleeping Sickness

Nov 16th, 2018 - The first oral-only treatment for human African trypanosomiasis (HAT), commonly known as sleeping sickness, has received a green light from the Committee for Human Medicinal Products (CHMP) of the European Medicines Agency (EMA). Fexinidazole Wint...

Novel Drug Approvals for 2021

Innovation drives progress. When it comes to innovation in the development of new drugs and therapeutic biological products, FDA’s Center for Drug Evaluation and Research (CDER) supports the pharmaceutical industry at every step of the process. Wi...

Advising Patients on Safe Travel Abroad

May 6th, 2011 - Specific Recommendations Arthropod-Borne Diseases Arthropods are not only a source of nuisance and pain at the site of their bites, but they also may cause more harmful generalized reactions as a result of venom production or allergies to substanc...

New FDA Orphan Drugs: IPI-504, Pafuramidine, Preos

Sep 21st, 2007 - September 21, 2007 — The US Food and Drug Administration (FDA) has granted orphan drug designation for IPI-504 for the treatment of gastrointestinal stromal tumors, pafuramidine for the treatment of African sleeping sickness, and PREOS for the tre...

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