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About 1,225 results

ALLMedicine™ Cryptosporidiosis Center

Research & Reviews  444 results

Development of Two Mouse Models for Vaccine Evaluation against Cryptosporidiosis.
https://doi.org/10.1128/iai.00127-22
Infection and Immunity; Dayao DA, Jaskiewcz J et. al.

Jun 24th, 2022 - Cryptosporidiosis was shown a decade ago to be a major contributor to morbidity and mortality of diarrheal disease in children in low-income countries. A serious obstacle to develop and evaluate immunogens and vaccines to control this disease is t...

A comparison of risk factors for cryptosporidiosis and non-cryptosporidiosis diarrhoea:...
https://doi.org/10.1371/journal.pntd.0010508
PLoS Neglected Tropical Diseases; Johansen ØH, Abdissa A et. al.

Jun 7th, 2022 - Cryptosporidiosis is a major cause of diarrhoea in young children in low-and-middle-income countries. New interventions should be informed by evidence pertaining to risk factors and their relative importance. Inconsistencies in the literature may ...

RNA-Based Therapy for Cryptosporidium parvum Infection: Proof-of-Concept Studies.
https://doi.org/10.1128/iai.00196-22
Infection and Immunity; Castellanos-Gonzalez A, Sadiqova A et. al.

Jun 2nd, 2022 - Cryptosporidium is a leading cause of moderate-to-severe diarrhea in children, which is one of the major causes of death in children under 5 years old. Nitazoxanide is the only FDA-approved treatment for cryptosporidiosis. However, it has limited ...

Prospects of halofuginone as an antiprotozoal drug scaffold.
https://doi.org/10.1016/j.drudis.2022.05.020
Drug Discovery Today; Gill J, Sharma A

Jun 1st, 2022 - Halofuginone is a clinically active derivative of febrifugine that was first isolated from the Chinese herb Dichroa febrifuga. The beneficial biological effects of halofuginone on various diseases including parasitic diseases, cancer, fibrosis, an...

Horse-Specific Cryptosporidium Genotype in Human with Crohn's Disease and Arthritis.
https://doi.org/10.3201/eid2806.220064
Emerging Infectious Diseases; Zajączkowska Ż, Brutovská AB et. al.

May 25th, 2022 - We identified an unusual subtype of a Cryptosporidium sp. horse genotype as the cause of cryptosporidiosis in a 13-year-old girl in Poland who was undergoing immunosuppressive treatment for juvenile rheumatoid arthritis and Crohn's disease. The sa...

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Clinicaltrials.gov  24 results

Treatment of Cryptosporidiosis
https://clinicaltrials.gov/ct2/show/NCT04103216

Mar 31st, 2022 - Background: Reports from longitudinal birth cohort study at Bangladesh show that 77% of children experience at least one incidence of cryptosporidiosis in the first two years of life. Cryptosporidiosis is also associated with the development of ma...

A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3
https://clinicaltrials.gov/ct2/show/NCT00000771

Nov 4th, 2021 - In previous studies, patients with cryptosporidiosis demonstrated dramatic improvement with paromomycin therapy. Patients are randomized to receive either placebo or paromomycin for 3 weeks. After the initial double-blind phase, all patients recei...

A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium
https://clinicaltrials.gov/ct2/show/NCT00001081

Nov 1st, 2021 - There is no proven therapy for cryptosporidiosis in persons with AIDS. Nitazoxanide appears to be a good candidate drug for further evaluation because of its effectiveness in preclinical models, the data from early clinical trials and its safety p...

Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children
https://clinicaltrials.gov/ct2/show/NCT00055107

Nov 1st, 2021 - C. parvum is a significant opportunistic infection in much of the developing world, where children may not have access to highly active antiretroviral therapy. There is currently no established therapy for chronic cryptosporidiosis in HIV infected...

Stool Transplants to Treat Refractory Clostridium Difficile Colitis
https://clinicaltrials.gov/ct2/show/NCT02127398

Sep 20th, 2021 - Recurrent colitis due to Clostridium difficile results from disruption of the normal gut flora, and is very difficult to treat. It is now clear that restoration of the normal gut flora is the most effective way to treat recurrent C. difficile coli...

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News  16 results

GSK, Novartis Pledge Funds for Neglected Tropical Diseases
https://www.medscape.com/viewarticle/976095

Jun 24th, 2022 - LONDON (Reuters) - GSK and Novartis reinforced commitments on Thursday to tackle neglected tropical diseases, as world leaders and health experts gather in Rwanda to discuss ways to better combat illnesses affecting more than a billion people, mos...

CDC Mandates Measles Quarantine for Afghanistan Evacuees
https://www.medscape.com/viewarticle/959222

Sep 22nd, 2021 - Evacuees of Afghanistan who have arrived in the United States must be vaccinated against measles and undergo quarantine for 21 days, according to a health advisory issued September 20 by the Centers for Disease Control and Prevention (CDC). At the...

Cryptosporidiosis Outbreak Rate Continues to Rise
https://www.medscape.com/viewarticle/915088

Jul 1st, 2019 - Outbreaks of a parasitic infection linked to swimming pools, farm animals, and childcare settings have risen steadily over the past decade, according to the Centers for Disease Control and Prevention (CDC). From 2009 to 2017, outbreaks of cryptosp...

Cryptosporidiosis infections spike during summer swim season
https://www.mdedge.com/familymedicine/article/203787/infectious-diseases/cryptosporidiosis-infections-spike-during-summer?channel=27970
MDedge Pediatrics; Heidi Splete

Jun 28th, 2019 - Outbreaks of cryptosporidiosis increased in the United States by an average of 13% each year between 2009 and 2017, based on data from the Centers for Disease Control and Prevention. In a study published in the CDC’s Morbidity and Mortality Weekly.

Cryptosporidiosis infections spike during summer swim season
https://www.mdedge.com/pediatrics/article/203787/infectious-diseases/cryptosporidiosis-infections-spike-during-summer-swim
Heidi Splete

Jun 28th, 2019 - Outbreaks of cryptosporidiosis increased in the United States by an average of 13% each year between 2009 and 2017, based on data from the Centers for Disease Control and Prevention. In a study published in the CDC’s Morbidity and Mortality Weekly.

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Patient Education  6 results see all →