About 9,538 results

ALLMedicine™ Leishmaniasis Center

Research & Reviews  3,583 results

Leishmania guyanensis M4147 as a new LRV1-bearing model parasite: Phosphatidate phospha...
PLoS Neglected Tropical Diseases; Zakharova A, Albanaz ATS et. al.

Jun 25th, 2022 - Leishmaniasis is a parasitic vector-borne disease caused by the protistan flagellates of the genus Leishmania. Leishmania (Viannia) guyanensis is one of the most common causative agents of the American tegumentary leishmaniasis. It has previously ...

Impaired in vitro Interferon-γ production in patients with visceral leishmaniasis is im...
PLoS Neglected Tropical Diseases; Takele Y, Adem E et. al.

Jun 25th, 2022 - Visceral leishmaniasis (VL) is a neglected tropical disease that causes substantial morbidity and mortality and is a growing health problem in Ethiopia, where this study took place. Most individuals infected with Leishmania donovani parasites will...

Immunotherapy for visceral leishmaniasis: A trapeze of balancing counteractive forces.
International Immunopharmacology; Mazire PH, Saha B et. al.

Jun 24th, 2022 - The protozoan parasite Leishmania donovani, residing and replicating within the cells of the monocyte-macrophage (mono-mac) lineage, causes visceral leishmaniasis (VL) in humans. While, Leishmania infantum, is the main causative agent for zoonotic...

Probing O-substituted Nifuroxazide analogues against Leishmania: Synthesis, in vitro ef...
European Journal of Pharmaceutical Sciences : Official Jo... Badenhorst GD, Kannigadu C et. al.

Jun 23rd, 2022 - Leishmaniasis is a neglected tropical disease affecting millions of people worldwide, with 650 000 to 1.1 million new infections reported annually by the World Health Organization. Current antileishmanial treatments are unsatisfactory due to the d...

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Guidelines  4 results

Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectiou...
Clinical Infectious Diseases : an Official Publication Of... Aronson N, Herwaldt BL et. al.

Dec 13th, 2016 - It is important to realize that leishmaniasis guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. The ID...

Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectiou...
The American Journal of Tropical Medicine and Hygiene; Aronson N, Herwaldt BL et. al.

Dec 9th, 2016 - Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH).|2016|Aronson N,Herwaldt BL,Libman M,Pearson R,Lopez-Vele...

Control of visceral leishmaniasis in Brazil: recommendations from Brasileish.
Parasites & Vectors; Ribeiro VM, da Silva SM et. al.

Jan 15th, 2013 - On 26 October 2012, veterinary medicine clinicians and researchers, members of Brasileish - Study Group about Animal Leishmaniasis - met at the Regional Council of Veterinary Medicine of Minas Gerais, in the city Belo Horizonte, in order to discus...

Designing and reporting clinical trials on treatments for cutaneous leishmaniasis.
Clinical Infectious Diseases : an Official Publication Of... González U, Pinart M et. al.

Jul 14th, 2010 - Cutaneous leishmaniasis is considered to be one of the most neglected and serious parasitic infectious skin diseases in many developing countries. We have assessed the design and reporting of randomized, controlled trials evaluating treatments inc...

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Drugs  2 results see all →

Clinicaltrials.gov  164 results

Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of Cure

Jun 22nd, 2022 - CONTEXT Visceral leishmaniasis (VL), or kala-azar, is caused by parasitic protozoa of the Leishmania donovani species complex, which are transmitted by the bite of infected female phlebotomine sand flies. VL has a worldwide distribution throughout...

Treatment of Mucosal Bolivian Leishmaniasis

Jun 15th, 2022 - The purpose of this protocol is to conduct a randomized comparison of the efficacy and tolerance of miltefosine, LAMB, and pentavalent antimony for the treatment of mucosal leishmaniasis. With such controlled pharmacodynamic data, and additional c...

Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis

Jun 8th, 2022 - Arnica tincture is a topical preparation based on the plant legally authorized in the countries of the European community, and it is included in the vademecun of medicinal plants in Colombia. The research product is the commercial phytotherapeutic...

Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa

Jun 6th, 2022 - Primary objective and endpoint: To evaluate the performance of different diagnostic tests in detecting anti-Leishmania antibodies to improve early diagnosis of VL in eastern Africa, in particular Ethiopia, and Kenya. Evaluation of the diagnostic p...

Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis.

Jun 3rd, 2022 - Curaleish is a topical formulation in lotion and cream that contains natural extracts (hydroalcoholic and glycolic for lotion and cream, respectively) of the branches (stems and leaves) of the Caesalpinia spinosa tree known as "Tara" or "Davidivi"...

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News  61 results

GSK, Novartis Pledge Funds for Neglected Tropical Diseases

Jun 24th, 2022 - LONDON (Reuters) - GSK and Novartis reinforced commitments on Thursday to tackle neglected tropical diseases, as world leaders and health experts gather in Rwanda to discuss ways to better combat illnesses affecting more than a billion people, mos...

Slow-Growing Pink Nodule in an Active-Duty Service Member
Travis Frantz, MD, McKay Frandsen, DO et. al.

Feb 17th, 2022 - The Diagnosis: Leishmaniasis Hematoxylin and eosin staining of the tissue specimen revealed a dense histiocytic infiltrate with scattered lymphocytes and neutrophils. There were round to oval basophilic structures within the macrophages consistent.

Miltefosine Granted Orphan Drug Approval for Invasive Candidiasis

Nov 12th, 2021 - The US Food and Drug Administration (FDA) has granted orphan drug designation approval of miltefosine (Profounda, Inc) for the treatment of invasive candidiasis. This condition includes the potentially life-threatening candidemia, which is among t...

The tryptophan photoproduct FICZ and its effects on the skin
Leslie S. Baumann, MD

Oct 15th, 2021 - The melatonin precursor tryptophan, an amino acid essential in the human diet, has been shown to display antioxidant effects. 1 FICZ (also known as 6-formylindolo[3,2-b]carbazole) is a photoproduct of tryptophan that is engendered by exposure to UV.

CDC Mandates Measles Quarantine for Afghanistan Evacuees

Sep 22nd, 2021 - Evacuees of Afghanistan who have arrived in the United States must be vaccinated against measles and undergo quarantine for 21 days, according to a health advisory issued September 20 by the Centers for Disease Control and Prevention (CDC). At the...

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Patient Education  1 results see all →