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About 42,490 results

ALLMedicine™ Malaria Center

Research & Reviews  15,626 results

Prevalence of potential mediators of artemisinin resistance in African isolates of Plas...
https://doi.org/10.1186/s12936-021-03987-6
Malaria Journal; Owoloye A, Olufemi M et. al.

Dec 4th, 2021 - The devastating public health impact of malaria has prompted the need for effective interventions. Malaria control gained traction after the introduction of artemisinin-based combination therapy (ACT). However, the emergence of artemisinin (ART) p...

Making a good malaria vaccine better.
https://doi.org/10.1016/j.pt.2021.11.006
Trends in Parasitology; Duffy PE

Dec 4th, 2021 - Last month, the World Health Organization (WHO) recommended widespread use of RTS,S/AS01 vaccine to prevent malaria in young African children, noting its 30% reduction in deadly severe malaria. In a recent report, Das et al. describe antibody effe...

Financially-Incentives to Improve Provider Compliance
https://clinicaltrials.gov/ct2/show/NCT04634019

Dec 3rd, 2021 - The main idea of the intervention is to conduct quarterly provider knowledge assessments at health facilities and to pay facilities a bonus if providers perform well on these tests. For the intervention, 12 clinical vignettes were created. These v...

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Guidelines  4 results

Updated CDC Recommendations for Using Artemether-Lumefantrine for the Treatment of Unco...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898222
MMWR. Morbidity and Mortality Weekly Report; Ballard SB, Salinger A et. al.

Apr 13th, 2018 - Malaria infection during pregnancy is associated with an increased risk for maternal and fetal complications. In the United States, treatment options for uncomplicated, chloroquine-resistant Plasmodium falciparum and P. vivax malaria in pregnant w...

Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-expos...
https://www.ncbi.nlm.nih.gov/pubmed/19730409
MMWR. Recommendations and Reports : Morbidity and Mortali... Mofenson LM, Brady MT et. al.

Sep 5th, 2009 - This report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (OIs) among HIV-exposed and HIV-infected children, last published in 2002 and 2004, respectively. These guidelin...

Guidance on the evaluation of Plasmodium vivax vaccines in populations exposed to natur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844894
Vaccine Mueller I, Moorthy VS et. al.

Jul 30th, 2009 - In this paper we give guidance for the design and conduct of vaccine trials against Plasmodium vivax malaria. The paper supplements earlier guidelines on the planning of vaccine trials against Plasmodium falciparum malaria [WHO. Guidelines for the...

Treatment and prevention of malaria in pregnancy and newborn.
https://doi.org/10.1515/JPM.2008.002
Journal of Perinatal Medicine; Coll O, Menendez C et. al.

Jan 11th, 2008 - Pregnant women are at increased risk for malaria infection. Although important advances have been made in the last years, the mechanisms that explain the increased susceptibility are not yet fully understood. Malaria infection in pregnancy is asso...

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Drugs  197 results see all →

Clinicaltrials.gov  453 results

Financially-Incentives to Improve Provider Compliance
https://clinicaltrials.gov/ct2/show/NCT04634019

Dec 3rd, 2021 - The main idea of the intervention is to conduct quarterly provider knowledge assessments at health facilities and to pay facilities a bonus if providers perform well on these tests. For the intervention, 12 clinical vignettes were created. These v...

Dynamic CDSA to Manage Sick Children in Tanzania
https://clinicaltrials.gov/ct2/show/NCT05144763

Dec 3rd, 2021 - Children are a well-recognized vulnerable population that still suffers from a high rate of acute infectious diseases and preventable deaths. This is especially true in fragile health systems of Sub-Saharan Africa, where under-five mortality is 10...

Blood-Stage Plasmodium Vivax Cell Bank
https://clinicaltrials.gov/ct2/show/NCT05095272

Dec 3rd, 2021 - This is a single-center, open-label study using induced blood-stage malaria (IBSM) to produce a human malaria parasite (HMP) bank for use in future studies. This study will be conducted in up to two participants. Participants will be inoculated in...

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease
https://clinicaltrials.gov/ct2/show/NCT03685721

Dec 2nd, 2021 - Polymerization of deoxy-sickle-hemoglobin (deoxy-HbS), the root cause of sickle cell disease (SCD) is influenced by a few factors, a key factor is 2,3-diphosphoglycerate (2,3-DPG) concentration in the red blood cells. 2,3-DPG is an allosteric effe...

Malaria Surveillance in Rakai, Uganda
https://clinicaltrials.gov/ct2/show/NCT01265407

Nov 30th, 2021 - Malaria is a leading cause of morbidity and mortality in Uganda, accounting for 25-40 percent of all outpatient visits at health facilities, 20 percent of hospital admissions, and 9-14 percent of inpatient deaths. Malaria is meso- to holoendemic i...

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News  703 results

I Am CDC- Bunmi Akinkugbe
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/415949

I work for the Division of Global Migration and Quarantine as the Officer-in-Charge of the CDC Atlanta Quarantine Station at Hartsfield Jackson Atlanta International Airport, the world’s busiest airport. I’m a public health first responder, leadin...

Why Have We Waited So Long for a Malaria Vaccine?
https://www.medscape.com/viewarticle/962419

Nov 9th, 2021 - Amed Ouattara, PhD Despite a global effort to eradicate malaria, a large malaria burden persists, in part due to the repeated emergence of parasite resistance to antimalarial drugs and mosquito resistance to insecticides. In 2019, an estimated 229...

Nebraska AG: Docs Can Prescribe Controversial COVID Drugs
https://www.medscape.com/viewarticle/961011

Oct 15th, 2021 - OMAHA, Neb. (AP) — Nebraska's attorney general said Friday that he won't seek disciplinary action against doctors who prescribe controversial, off-label drugs to treat and prevent coronavirus infections, as long as they get informed consent from p...

African Union to Start Talks With WHO on Malaria Vaccine Rollout on Continent
https://www.medscape.com/viewarticle/960438

Oct 8th, 2021 - NAIROBI (Reuters) - Africa will start talks with the World Health Organization about getting the first approved malaria vaccine to the continent as soon as possible, the African Union's top health official said on Thursday, amid calls for funding ...

Global Burden of Plasmodium vivax Malaria Is Much Greater Than Previously Thought
https://www.medscape.com/viewarticle/960484

Oct 8th, 2021 - The burden of Plasmodium vivax malaria has been grossly underestimated, according to a report in PLOS Medicine. The study was conducted by J. Kevin Baird, PhD, Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, and colleagues. There are fi...

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Patient Education  13 results see all →