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About 42,550 results

ALLMedicine™ Herpes Center

Research & Reviews  19,187 results

Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid ...
https://doi.org/10.1136/jitc-2020-002224
Journal for Immunotherapy of Cancer; Zhang B, Huang J et. al.

Apr 10th, 2021 - OH2 is a genetically engineered oncolytic herpes simplex virus type 2 designed to selectively amplify in tumor cells and express granulocyte-macrophage colony-stimulating factor to enhance antitumor immune responses. We investigated the safety, to...

Anterograde transport of α-herpesviruses in neuronal axons.
https://doi.org/10.1016/j.virol.2021.02.011
Virology DuRaine G, Johnson DC

Apr 9th, 2021 - α-herpesviruses have been very successful, principally because they establish lifelong latency in sensory ganglia. An essential piece of the lifecycle of α-herpesviruses involves the capacity to travel from sensory neurons to epithelial tissues fo...

Roseola Infantum During the COVID-19 Pandemic.
https://doi.org/10.1097/MPH.0000000000002163
Journal of Pediatric Hematology/oncology; Aktürk H, Bağci MS et. al.

Apr 8th, 2021 - Roseola infantum is always considered to be among the differential diagnosis of young patients with fever and leukopenia whom to be strictly isolated with the preliminary diagnosis of COVID-19 until otherwise proven during the pandemic. Human herp...

Herpes simplex virus esophagitis-clinical challenges in the elderly.
https://doi.org/10.1136/bcr-2020-240956
BMJ Case Reports; Custódio SF, Félix C et. al.

Apr 8th, 2021 - A 77-year-old woman presented with a 2-week history of malaise, prostration, anorexia, abdominal pain, vomiting and diarrhoea. She had been taking systemic corticosteroids for the past year. During hospitalisation, renal insufficiency, ionic chang...

Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0ΔNLS vaccine ...
https://doi.org/10.1016/j.vaccine.2021.03.075
Vaccine Carr DJJ, Berube AN et. al.

Apr 5th, 2021 - The neonatal Fc receptor (FcRn) is constitutively expressed in the cornea and is up-regulated in response to herpes simplex virus type 1 (HSV-1). Previously, we found targeting cornea FcRn expression by small interfering RNA-mediated knockdown red...

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Guidelines  157 results

Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?
https://pubmed.ncbi.nlm.nih.gov/32888876/
Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology; Brandão TB, Gueiros LA et. al.

Feb 14th, 2021 - Several viruses transmitted through saliva, such as herpes simplex virus, cytomegalovirus, and Zika virus, are capable of infecting and replicating in the oral mucosa, leading to painful oral ulcers. Few studies have described the oral manifestati...

Bullous Disseminated Herpes Zoster: An Atypical Presentation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437097/
Cureus Jethwa T

Jul 19th, 2020 - Herpes zoster is an infection resulting from the reactivation of dormant varicella zoster virus (VZV) in a posterior dorsal root ganglion. It affects 50% of immunocompromised patients and, when the viral infection persists, it can lead to a proces...

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin Summary, Number 220.
https://doi.org/10.1097/AOG.0000000000003841
Obstetrics and Gynecology Reference;

Apr 25th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin...
https://doi.org/10.1097/AOG.0000000000003840
Obstetrics and Gynecology;

Apr 25th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Genital Ulcers: Differential Diagnosis and Management
https://www.aafp.org/afp/2020/0315/p355.html
American Family Physician; Roett MA,et al

Mar 14th, 2020 - Genital ulcers may be located on the vagina, penis, and anorectal or perineal areas and may be infectious or noninfectious. Herpes simplex virus is the most common cause of genital ulcers in the United States. A diagnosis of genital herpes simplex...

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Drugs  941 results see all →

Clinicaltrials.gov  20,847 results

Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid ...
https://doi.org/10.1136/jitc-2020-002224
Journal for Immunotherapy of Cancer; Zhang B, Huang J et. al.

Apr 10th, 2021 - OH2 is a genetically engineered oncolytic herpes simplex virus type 2 designed to selectively amplify in tumor cells and express granulocyte-macrophage colony-stimulating factor to enhance antitumor immune responses. We investigated the safety, to...

Anterograde transport of α-herpesviruses in neuronal axons.
https://doi.org/10.1016/j.virol.2021.02.011
Virology DuRaine G, Johnson DC

Apr 9th, 2021 - α-herpesviruses have been very successful, principally because they establish lifelong latency in sensory ganglia. An essential piece of the lifecycle of α-herpesviruses involves the capacity to travel from sensory neurons to epithelial tissues fo...

Roseola Infantum During the COVID-19 Pandemic.
https://doi.org/10.1097/MPH.0000000000002163
Journal of Pediatric Hematology/oncology; Aktürk H, Bağci MS et. al.

Apr 8th, 2021 - Roseola infantum is always considered to be among the differential diagnosis of young patients with fever and leukopenia whom to be strictly isolated with the preliminary diagnosis of COVID-19 until otherwise proven during the pandemic. Human herp...

Herpes simplex virus esophagitis-clinical challenges in the elderly.
https://doi.org/10.1136/bcr-2020-240956
BMJ Case Reports; Custódio SF, Félix C et. al.

Apr 8th, 2021 - A 77-year-old woman presented with a 2-week history of malaise, prostration, anorexia, abdominal pain, vomiting and diarrhoea. She had been taking systemic corticosteroids for the past year. During hospitalisation, renal insufficiency, ionic chang...

Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0ΔNLS vaccine ...
https://doi.org/10.1016/j.vaccine.2021.03.075
Vaccine Carr DJJ, Berube AN et. al.

Apr 5th, 2021 - The neonatal Fc receptor (FcRn) is constitutively expressed in the cornea and is up-regulated in response to herpes simplex virus type 1 (HSV-1). Previously, we found targeting cornea FcRn expression by small interfering RNA-mediated knockdown red...

see more →

News  1,353 results

A 53-Year-Old Man With Worsening Heartburn: Osmosis USMLE Study Question
https://www.medscape.com/viewarticle/855326

Mar 18th, 2021 - Test yourself with this question from Osmosis.org and see how you stack up against your peers! A 53-year-old man presents for an outpatient visit complaining of minor heartburn that has been ongoing for 7 years. He occasionally takes antacids, whi...

Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?
https://pubmed.ncbi.nlm.nih.gov/32888876/
Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology; Brandão TB, Gueiros LA et. al.

Feb 14th, 2021 - Several viruses transmitted through saliva, such as herpes simplex virus, cytomegalovirus, and Zika virus, are capable of infecting and replicating in the oral mucosa, leading to painful oral ulcers. Few studies have described the oral manifestati...

MHRA Updates Safety Advice on Fingolimod
https://www.medscape.com/viewarticle/944262

Jan 17th, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has strengthened the safety warnings for fingolimod (Gilenya), highlighting the risks of serious liver injury and herpes meningoencephalitis. A recent European review identified seven ...

Acute Non-PHN Complications of Herpes Zoster
https://www.medscape.com/viewarticle/941590

Nov 24th, 2020 - Acute complications of herpes zoster (HZ) other than post-herpetic neuralgia (PHN) are relatively common, a new study suggests. Researchers conducted a cohort study of unvaccinated immunocompetent adults with incident HZ (n=178,964) and matched to...

A 38-Year-Old Dog Owner With a Blistering, Itchy Rash
https://reference.medscape.com/viewarticle/939533_3

Oct 28th, 2020 - Discussion Herpes simplex virus infection can affect almost any area of the skin or mucous membranes and presents with localized blistering. Isolation of the virus in tissue culture confirms the diagnosis.[1] In this case, the viral and bacterial ...

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Patient Education  65 results see all →