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ALLMedicine™ Orf Center

Research & Reviews  1,189 results

The complete genome sequence of Indian Sheeppox vaccine virus and comparative analysis ...
https://doi.org/10.1016/j.gene.2021.146085
Gene Kumar A, Venkatesan G et. al.

Nov 30th, 2021 - Sheeppox virus (SPPV) is responsible for a significant economic loss to sheep husbandry in enzootic regions of Africa, the Middle East, and Asia including the Indian subcontinent. In this study, we present the complete genome sequence of SPPV vacc...

Silencing of cytochrome P450 gene CYP321A1 effects tannin detoxification and metabolism...
https://doi.org/10.1016/j.ijbiomac.2021.11.144
International Journal of Biological Macromolecules; Zhao P, Xue H et. al.

Nov 30th, 2021 - Cytochrome P450 monooxygenase (P450 or CYP) plays an important role in the metabolism of insecticides and plant allelochemicals by insects. CYP321B1, a novel Spodoptera litura P450 gene, was identified and characterized. CYP321B1 contains a 1488 b...

Nickel nanoparticle-induced cell transformation: involvement of DNA damage and DNA repa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600818
Journal of Nanobiotechnology; Mo Y, Zhang Y et. al.

Nov 19th, 2021 - Nickel nanoparticles (Nano-Ni) are increasingly used in industry and biomedicine with the development of nanotechnology. However, the genotoxic and carcinogenic effects of Nano-Ni and the underlying mechanisms are still unclear. At first, dose-res...

Functional screen of inflammatory bowel disease genes reveals key epithelial functions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582123
Genome Medicine; Ntunzwenimana JC, Boucher G et. al.

Nov 12th, 2021 - Genetic studies have been tremendously successful in identifying genomic regions associated with a wide variety of phenotypes, although the success of these studies in identifying causal genes, their variants, and their functional impacts has been...

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Clinicaltrials.gov  4 results

Fight COVID-19 Trial
https://clinicaltrials.gov/ct2/show/NCT04303299

Sep 2nd, 2021 - Overall Study Design and Plan Various Combination of Protease inhibitors, Oseltamivir, Favipiravir, and Chloroquin for treatment of COVID-19. Non parametric and parametric statistical analysis will be analysed in the efficacy of treatment. For the...

A Study of BBP-711 (ORF-229) in Healthy Adult Volunteers
https://clinicaltrials.gov/ct2/show/NCT04876924

May 12th, 2021 - This is a single-center, two-part, randomized, double-blinded, placebo-controlled, ascending dose study of BBP-711 in healthy male and female adult volunteers. The purpose of this study is to evaluate the safety and tolerability of BBP-711 in heal...

The Treatment With HBIG+GM-CSF+HBV Vaccine for Chronic Hepatitis B Patients With HBeAg Seroconversion
https://clinicaltrials.gov/ct2/show/NCT01878565

Jul 24th, 2013 - The host immunity has been generally recognized as the main factors to determine the outcome of chronic hepatitis B virus (HBV) infection. Previous studies have shown that HBV-specific T cell and B cell function are exhausted in chronic hepatitis ...

Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
https://clinicaltrials.gov/ct2/show/NCT01160614

Oct 15th, 2012 - The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.

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News  7 results

Austria Plans to Start COVID-19 Booster Shots in October
https://www.medscape.com/viewarticle/956313

Aug 11th, 2021 - VIENNA (Reuters) - Austria plans to start COVID-19 vaccine booster shots on Oct. 17, nine months after the first group of people to get the jabs received their second dose, the country's health minister said on Tuesday. The first wave included vul...

Austria reports first MERS case in Saudi national: media
https://www.reuters.com/article/us-austria-mers/austria-reports-first-mers-case-in-saudi-national-media-idUSKCN0HP0EN20140930

Sep 30th, 2014 - VIENNA (Reuters) - Austria has reported its first case of the Middle East Respiratory Syndrome (MERS) virus in a woman from Saudi Arabia who had recently traveled to the Alpine country, ORF Oe 1 radio reported on Tuesday, citing the health ministr...

U.S. agency warns of skin lesions from goats, sheep
https://www.reuters.com/article/us-usa-meat-lesions/u-s-agency-warns-of-skin-lesions-from-goats-sheep-idUSBRE83B1OK20120412

Apr 12th, 2012 - ATLANTA (Reuters) - People can contract skin lesions from goats and sheep infected with the Orf virus through household meat preparation or when slaughtering the animals, a federal agency said on Thursday in a report aimed at doctors in ethnically...

A Case of Human Orf Contracted From a Deer
https://www.mdedge.com/dermatology/article/66900/infectious-diseases/case-human-orf-contracted-deer
John T. Kuhl, BS, Christopher J. Huerter, MD et. al.

Orf, also known as contagious ecthyma, scabby mouth, soremouth, contagious pustular dermatitis, and ovine pustular dermatitis, is caused by a member of the genus Parapoxvirus in the family Poxviridae. 1,2 The virus typically infects sheep or goats.

Hepatitis B and C Virus Infection and Risk of Haematological Malignancies
https://www.staging.medscape.com/viewarticle/923071_3

Relatioship Between HBV Infection and Haematological Malignancies Hepatitis B virus is a small 3.2 Kb DNA virus belonging to the Hepadnaviridae family. HBV DNA replicates by reverse transcription of an RNA intermediate.[33] Thus, during viral infe...

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