×
About 4,958 results

ALLMedicine™ Avian Influenza Center

Research & Reviews  1,791 results

Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in h...
https://doi.org/10.1128/JVI.00906-21
Journal of Virology; Bestle D, Limburg H et. al.

Jul 29th, 2021 - Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs possess a monobasic HA cleavage site cleaved by trypsin-like proteases. Previously, the transmembrane protease TMPRSS2 w...

Highly Pathogenic Avian Influenza A(H5N8) Virus Clade 2.3.4.4b, Western Siberia, Russia...
https://doi.org/10.3201/eid2708.204969
Emerging Infectious Diseases; Sobolev I, Sharshov K et. al.

Jul 22nd, 2021 - Two variants of highly pathogenic avian influenza A(H5N8) virus were detected in dead poultry in Western Siberia, Russia, during August and September 2020. One variant was represented by viruses of clade 2.3.4.4b and the other by a novel reassorta...

Cytokines Can Suppress Cardiac Output and Cytokine Storms Inhibit Oxygen Use by Mitocho...
https://doi.org/10.1097/CCM.0000000000004991
Critical Care Medicine; Honore PM, Redant S et. al.

Jul 16th, 2021 - Cytokines Can Suppress Cardiac Output and Cytokine Storms Inhibit Oxygen Use by Mitochondria and Contribute to the Occurrence of Acute Heart Failure in Patients With Severe Infection Caused by Avian Influenza A (H7N9): We Are Not Sure!|2021|Honore...

RNA-dependent assembly of chimeric antigen nanoparticles as an efficient H5N1 pre-pande...
https://doi.org/10.1016/j.nano.2021.102438
Nanomedicine : Nanotechnology, Biology, and Medicine; Lim J, Cheong Y et. al.

Jul 14th, 2021 - Highly pathogenic avian influenza viruses (HPAIVs) pose a significant threat to human health, with high mortality rates and require effective vaccines. We showed that, harnessed with novel RNA-mediated chaperone function, hemagglutinin (HA) of H5N...

Emergence of a young case infected with avian influenza A (H5N6) in Anhui Province, Eas...
https://doi.org/10.1002/jmv.27179
Journal of Medical Virology; Yu JL, Hou S et. al.

Jul 8th, 2021 - In the context of the coronavirus disease 2019 pandemic, we investigated the epidemiological and clinical characteristics of a young patient infected by avian influenza A (H5N6) virus in Anhui Province, East China, and analyzed genomic features of...

see more →

Clinicaltrials.gov  31 results

Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian Influenza
https://clinicaltrials.gov/ct2/show/NCT03682120

May 1st, 2020 - This is a randomized, double-blinded, Phase II study in healthy males and non-pregnant females, 18-64 years of age. This clinical trial is designed to assess the safety, reactogenicity, and immunogenicity of a pre-pandemic 2017 monovalent inactiva...

Safety and Immunogencity of H7N9 Influenza Antigen With 2 Adjuvant Formulations in Healthy Adults in Brazil
https://clinicaltrials.gov/ct2/show/NCT03330899

Sep 26th, 2018 - Following the emergence of avian influenza A/H7N9 influenza virus in humans in China in March 2013, the WHO Essential Regulatory Laboratories prepared candidate vaccine viruses and reagents for further development and several manufacturers have de...

A Study to Evaluate Safety, Immunogenicity, and Lot-to-Lot Consistency of H5N1 Subunit Influenza Virus Vaccine in Healthy Adult Subjects ≥18 Years of Age
https://clinicaltrials.gov/ct2/show/NCT02839330

Aug 8th, 2018 - This Phase 3 study evaluates the safety, immunogenicity and lot-to lot consistency of 3 lots of aH5N1c vaccine for pandemic avian influenza, in approximately 2394 healthy adults ≥18 years of age receiving the vaccine and 798 healthy adults receivi...

Development of Immune Globulin Treatment for Avian Flu
https://clinicaltrials.gov/ct2/show/NCT00383071

Jul 31st, 2018 - Avian influenza presents a threat of a future pandemic. Over 200 people have been infected with the influenza A H5N1 virus, and the mortality is near 60 percent. Optimal therapy is not known, and failures of and resistance to currently available a...

A Trial to Test the Response to Different Vaccination Regimens With an H5N1 Vaccine With AS03 in Adults Aged 18-64
https://clinicaltrials.gov/ct2/show/NCT00695669

Jul 31st, 2018 - A Phase 2, open-label, randomized, parallel group, multi-centered study designed to evaluate the immunogenicity and safety of a 2-dose series of avian influenza vaccine plus AS03 adjuvant according to different regimens, in adults aged 18-64 years...

see more →

News  159 results

U.S. detects its first case of virulent bird flu in commercial poultry since 2017
https://www.reuters.com/article/us-health-birdflu-usa/u-s-detects-its-first-case-of-virulent-bird-flu-in-commercial-poultry-since-2017-idUSKCN21R3DS

Apr 9th, 2020 - CHICAGO (Reuters) - The U.S. Department of Agriculture on Thursday confirmed the country’s first case of virulent avian flu in commercial poultry since 2017. The agency found H7N3 avian influenza, a virulent or highly pathogenic strain, in a turke...

The Return of the Plague: A Primer on Pandemic Ethics
https://www.mdedge.com/cardiology/article/219909/health-policy/return-plague-primer-pandemic-ethics?channel=52
Cynthia M.A. Geppert, MD

Mar 31st, 2020 - I am writing this editorial on a beautiful day in the high desert of the Southwest: a bright blue clear sky such as you see only in the mountain air, a sun warm and comforting, and birds singing as if they had not a care in the world. Spring has c.

Vietnam culls 137,000 birds to contain avian influenza outbreaks
https://www.reuters.com/article/us-vietnam-birdflu/vietnam-culls-137000-birds-to-contain-avian-influenza-outbreaks-idUSKBN20S18T

Mar 5th, 2020 - HANOI (Reuters) - Vietnam has so far this year culled 137,180 birds to contain the spreading of bird flu outbreaks, the government said on Thursday. The outbreaks, including 38 outbreaks of H5N6 and five outbreaks of H5N1, have been detected in 13...

Chicken Cull After Suffolk Bird Flu Outbreak
https://www.medscape.com/viewarticle/922449

Dec 11th, 2019 - Twenty-seven thousand chickens are being culled on a farm in Suffolk after avian influenza was confirmed there. A 1km restricted zone has been put in place around the farm. Public Health England (PHE) said in a statement: "Low pathogenic avian inf...

Chicken Cull After Suffolk Bird Flu Outbreak
https://www.staging.medscape.com/viewarticle/922449

Dec 11th, 2019 - Twenty-seven thousand chickens are being culled on a farm in Suffolk after avian influenza was confirmed there. A 1km restricted zone has been put in place around the farm. Public Health England (PHE) said in a statement: "Low pathogenic avian inf...

see more →

Patient Education  2 results see all →