ALLMedicine™ Vaccinia Center

Feb 26th, 2021 - Bacille-Calmette-Guerin (BCG) has variable efficacy as an adult tuberculosis (TB) vaccine but can reduce the incidence and severity of TB infection in humans. We have engineered modified vaccinia Ankara (MVA) strain vaccine constructs to express t...

Feb 25th, 2021 - A combination of vaccination approaches will likely be necessary to fully control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Here, we show that modified vaccinia Ankara (MVA) vectors expressing membrane-anchored pre...

Feb 19th, 2021 - Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases. It also finds a new place in onc...

Feb 13th, 2021 - Oncolytic virotherapy with vaccinia virus (VV) can lead to effective anti-tumor immunity by turning "cold" tumors into "hot" tumors. However, its therapeutic potential is affected by the tumor's local immunosuppressive tumor microenvironment (TME)...

Feb 13th, 2021 - Background Human cancers are extraordinarily heterogeneous in terms of tumor antigen expression, immune infiltration and composition. A common feature, however, is the host's inability to mount potent immune responses that prevent tumor growth eff...

Apr 27th, 2012 - Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that ART practitioners consider deferring donors who have recently received smallpox vaccine or con...

Nov 25th, 2008 - Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that ART practitioners consider deferring donors who have recently received smallpox vaccine or con...

Feb 26th, 2021 - Bacille-Calmette-Guerin (BCG) has variable efficacy as an adult tuberculosis (TB) vaccine but can reduce the incidence and severity of TB infection in humans. We have engineered modified vaccinia Ankara (MVA) strain vaccine constructs to express t...

Feb 25th, 2021 - A combination of vaccination approaches will likely be necessary to fully control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Here, we show that modified vaccinia Ankara (MVA) vectors expressing membrane-anchored pre...

Feb 19th, 2021 - Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases. It also finds a new place in onc...

Feb 13th, 2021 - Oncolytic virotherapy with vaccinia virus (VV) can lead to effective anti-tumor immunity by turning "cold" tumors into "hot" tumors. However, its therapeutic potential is affected by the tumor's local immunosuppressive tumor microenvironment (TME)...

Feb 13th, 2021 - Background Human cancers are extraordinarily heterogeneous in terms of tumor antigen expression, immune infiltration and composition. A common feature, however, is the host's inability to mount potent immune responses that prevent tumor growth eff...

Oct 18th, 2020 - NEW YORK (Reuters Health) - Sequential administration of two different Ebola vaccines spaced several weeks apart yields the best antibody responses, according to an early trial. Dr. Neil Goldstein of Janssen Infectious Diseases and Vaccines, in Le...

Feb 10th, 2020 - NEW YORK (Reuters Health) - Patients who underwent an allogeneic hematopoietic stem cell transplant (HCT) experienced fewer cytomegalovirus (CMV)-related complications after Triplex vaccine injections in a phase-2, randomized, placebo-controlled t...

Feb 10th, 2020 - NEW YORK (Reuters Health) - Patients who underwent an allogeneic hematopoietic stem cell transplant (HCT) experienced fewer cytomegalovirus (CMV)-related complications after Triplex vaccine injections in a phase-2, randomized, placebo-controlled t...

Oct 30th, 2019 - A laboratory worker in San Diego, CA, infected herself with a smallpox-related virus after she accidentally pricked her finger during an experiment. The 26-year-old was injecting a mouse with the vaccinia virus (VACV) in 2018 when the needle pierc...

Sep 25th, 2019 - The Food and Drug Administration has approved Jynneos, a live, nonreplicating vaccine based on the vaccinia virus, for smallpox and monkeypox, becoming the first FDA-approved vaccine for the prevention of monkeypox disease. FDA approval for Jynneo.