ALLMedicine™ Herpes Simplex Center

Jan 15th, 2022 - Congenital corneal opacity (CCO) is a rare disorder. Penetrating keratoplasty (PK) is the main surgical option for CCO, but many factors affect graft survival. Therefore, this study aimed to perform a virological examination of CCO specimens after...

Jan 15th, 2022 - Yunnan has the highest rates of HIV in China. Other treatable sexually transmitted infections (STIs) are associated with accelerated HIV transmission and poor ART outcomes, but are only diagnosed by syndromic algorithms. We recruited 406 HIV-posit...

Jan 14th, 2022 - This is a prospective, randomized clinical trial looking to determine the role of prophylactic treatment with topical corticosteroids in preventing recurrences in patients with a history of infectious epithelial keratitis, stromal keratitis,endoth...

Jan 14th, 2022 - Oncolytic herpes simplex virus-1 (oHSV) infection of brain tumors activates NOTCH, however the consequences of NOTCH on oHSV induced immunotherapy is largely unknown. Here we evaluated the impact of NOTCH blockade on virus induced immunotherapy. R...

Jan 14th, 2022 - Herpes simplex virus type 1 (HSV1) infects most humans and remains lifelong in the body in latent form within the PNS. The virus can be reactivated by stress, immunosuppression etc, and in some people it then causes cold sores.

Apr 26th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Apr 26th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Sep 5th, 2018 - To provide an updated joint ASCO/Infectious Diseases Society of America (IDSA) guideline on antimicrobial prophylaxis for adult patients with immunosuppression associated with cancer and its treatment. ASCO and IDSA convened an update Expert Panel...

Jul 22nd, 2017 - To provide recommendations for the management of genital herpes infection in women who want to get pregnant or are pregnant and for the management of genital herpes in pregnancy and strategies to prevent transmission to the infant. More effective ...

Dec 21st, 2016 - Genital herpes is a prevalent sexually transmitted infection in the United States, occurring in almost 1 in 6 persons aged 14 to 49 years. Infection is caused by 2 subtypes of the herpes simplex virus (HSV), HSV-1 and HSV-2. Antiviral medications ...

Jan 14th, 2022 - This is a prospective, randomized clinical trial looking to determine the role of prophylactic treatment with topical corticosteroids in preventing recurrences in patients with a history of infectious epithelial keratitis, stromal keratitis,endoth...

Dec 30th, 2021 - A microbicide is a drug or agent designed to prevent transmission of HIV. Griffithsin, or "GRFT", is an investigational product that is being developed as a microbicide. GRFT is a naturally occurring protein originally isolated from the red alga G...

Dec 1st, 2021 - COVID-19, caused by SARS-COV-2, was first reported in the city of Wuhan, Hubei province, China, at the end of December 2019. The exact origin of human infection has not yet been clearly identified.SARS-CoV-2 is a member of the Coronavirus family, ...

Nov 17th, 2021 - Study design and settings: This present study will be a randomized, placebo-controlled, double-blinded, multi-center trial to be conducted at 14 medical centers in tertiary hospitals with Neonatal Intensive Care Unit that were selected by the expe...

Nov 12th, 2021 - The aim of this study is to assess performance of using healthcare tools to understand genital Herpes Simplex Virus-2 (HSV-2) in patients ≥ 18 years of age in the United States and Europe. More specifically, the study aims to evaluate patient-repo...

Dec 16th, 2021 - The FDA granted accelerated approval for the first drug to reduce proteinuria in primary immunoglobulin A (IgA) nephropathy, the agency announced on Wednesday. The delayed released budesonide (Tarpeyo) capsules are indicated to lower increased pro...

Nov 14th, 2021 - Takeaway Atopic dermatitis (AD) was associated with an increased risk of hospitalised infections, opportunistic infections and several herpesvirus infections in both children and adults, with the risk being greatest in those with severe skin disea...

Oct 15th, 2021 - The Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended that the oral Janus kinase 1 inhibitor abrocitinib be granted marketing authorization in the European Union for treating atopic dermatitis (AD). Th...

Oct 12th, 2021 - Dedicator of cytokinesis 8 (DOCK8 ) deficiency is the major cause of autosomal-recessive hyper-IgEsyndrome. 1 Characteristic clinical features including eosinophilia, eczema, and recurrent Staphylococcus aureus cutaneous and respiratory tract infe.

Oct 6th, 2021 - Howard L. Kaufman, MD Talimogene laherparepvec (T-VEC) manifested significant gains in durable response rate (DRR) and other key clinical indicators in patients with advanced melanoma in what researchers described as the first phase III trial dem...