×
About 15,365 results

ALLMedicine™ Herpes Simplex Center

Research & Reviews  5,240 results

Potential Involvement of Varicella Zoster Virus in Alzheimer's Disease via Reactivation...
https://doi.org/10.3233/JAD-220287
Journal of Alzheimer's Disease : JAD; Cairns DM, Itzhaki RF et. al.

Jun 28th, 2022 - Varicella zoster virus (VZV) has been implicated in Alzheimer's disease (AD), and vaccination against shingles, caused by VZV, has been found to decrease the risk of AD/dementia. VZV might reside latently in brain, and on reactivation might cause ...

Herpes Simplex Virus 1 Expressing GFP-Tagged Virion Host Shutoff (vhs) Protein Uncouple...
https://doi.org/10.1128/jvi.01926-21
Journal of Virology; Wise EL, Samolej J et. al.

Jun 28th, 2022 - Virion host shutoff (vhs) protein is an endoribonuclease encoded by herpes simplex virus 1 (HSV1). vhs causes several changes to the infected cell environment that favor the translation of late (L) virus proteins: cellular mRNAs are degraded, imme...

Antiviral activity of triptolide on herpes simplex virus in vitro.
https://doi.org/10.1002/iid3.667
Immunity, Inflammation and Disease; Aliabadi N, Jamalidoust M et. al.

Jun 28th, 2022 - Herpes simplex virus-type 1 (HSV-1) can cause diseases, especially amongst neonates and immunocompromised hosts. Hence, developing a novel anti-HSV-1 drug with low-level toxicity is vital. Triptolide (TP), a diterpenoid triepoxide is a natural pro...

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
https://clinicaltrials.gov/ct2/show/NCT01176006

Jun 24th, 2022 - Background Mutations in the Dedicator of Cytokinesis-8 (DOCK8) gene are responsible for an immunodeficiency disease characterized by: severe cutaneous and sinopulmonary infections with bacterial organisms; extensive cutaneous viral infections with...

Study of the Safety of a Particular Herpes Vaccine in Adults With or Without Herpes Infection
https://clinicaltrials.gov/ct2/show/NCT01915212

Jun 24th, 2022 - Herpes simplex virus 2 (HSV-2) causes genital herpes and increases the risk of acquisition and transmission of HIV. An HSV-2 vaccine is not available. We will study a replication-defective HSV-2 vaccine, HSV529, that is deleted for 2 essential vir...

see more →

Guidelines  10 results

Management of herpesvirus reactivations in patients with solid tumours and hematologic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810475
Annals of Hematology; Henze L, Buhl C et. al.

Jan 8th, 2022 - Clinical reactivations of herpes simplex virus or varicella zoster virus occur frequently among patients with malignancies and manifest particularly as herpes simplex stomatitis in patients with acute leukaemia treated with intensive chemotherapy ...

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin...
https://doi.org/10.1097/AOG.0000000000003840
Obstetrics and Gynecology;

Apr 26th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin Summary, Number 220.
https://doi.org/10.1097/AOG.0000000000003841
Obstetrics and Gynecology Reference;

Apr 26th, 2020 - Genital herpes simplex virus (HSV) infection during pregnancy poses a risk to the developing fetus and newborn. Genital herpes is common in the United States. Among 14- to 49-year-old females, the prevalence of HSV-2 infection is 15.9%. However, t...

Antimicrobial Prophylaxis for Adult Patients With Cancer-Related Immunosuppression: ASC...
https://doi.org/10.1200/JCO.18.00374
Journal of Clinical Oncology : Official Journal of the Am... Taplitz RA, Kennedy EB et. al.

Sep 5th, 2018 - To provide an updated joint ASCO/Infectious Diseases Society of America (IDSA) guideline on antimicrobial prophylaxis for adult patients with immunosuppression associated with cancer and its treatment. ASCO and IDSA convened an update Expert Panel...

No. 208-Guidelines for the Management of Herpes Simplex Virus in Pregnancy.
https://doi.org/10.1016/j.jogc.2017.04.016
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Money DM, Steben M

Jul 22nd, 2017 - To provide recommendations for the management of genital herpes infection in women who want to get pregnant or are pregnant and for the management of genital herpes in pregnancy and strategies to prevent transmission to the infant. More effective ...

see more →

Drugs  150 results see all →

Clinicaltrials.gov  244 results

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
https://clinicaltrials.gov/ct2/show/NCT01176006

Jun 24th, 2022 - Background Mutations in the Dedicator of Cytokinesis-8 (DOCK8) gene are responsible for an immunodeficiency disease characterized by: severe cutaneous and sinopulmonary infections with bacterial organisms; extensive cutaneous viral infections with...

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
https://clinicaltrials.gov/ct2/show/NCT01011712

Jun 24th, 2022 - Viral infections in the normal host are usually self-limited as the innate and acquired immune systems mount successful antiviral responses. However, in some instances, apparently immunocompetent persons manifest infections with viruses that would...

Study of the Safety of a Particular Herpes Vaccine in Adults With or Without Herpes Infection
https://clinicaltrials.gov/ct2/show/NCT01915212

Jun 24th, 2022 - Herpes simplex virus 2 (HSV-2) causes genital herpes and increases the risk of acquisition and transmission of HIV. An HSV-2 vaccine is not available. We will study a replication-defective HSV-2 vaccine, HSV529, that is deleted for 2 essential vir...

Herpesviruses Reactivation In Hiv-Infected Women Initiating ART (HERA)
https://clinicaltrials.gov/ct2/show/NCT03092505

Jun 24th, 2022 - Initiation of antiretroviral therapy (ART) can lead to a short-term increase of herpes virus-related illnesses including genital herpes flares, higher likelihood of varicella zoster virus (VZV), cytomegalovirus (CMV) uveitis or other end-organ dis...

Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects
https://clinicaltrials.gov/ct2/show/NCT03073967

Jun 23rd, 2022 - The trial comprises 5 Parts, Part A, B, C, D and E. Part A and Part B (Phase 2) have been closed in November 2020. Part A is a randomized, open-label, multi-center, comparative design to assess the efficacy and safety in subjects with ACV-resistan...

see more →

News  486 results

Is Hepatitis C an STI?
https://www.medscape.com/viewarticle/975794

Jun 17th, 2022 - A 32-year-old woman had sex with a man she met while on vacation 6 weeks ago. She was intoxicated at the time and does not know much about the person. She recalls having engaged in vaginal intercourse without a condom. She does not have any sympto...

Is hepatitis C an STI?
https://www.mdedge.com/internalmedicine/article/255472/infectious-diseases/hepatitis-c-sti
Douglas S. Paauw, MD

Jun 15th, 2022 - A 32-year-old woman had sex with a man she met while on vacation 6 weeks ago. She was intoxicated at the time and does not know much about the person.

Administration of RP1 Through Intratumoral Injection Offers Unique Advantages in Melanoma Treatment
https://www.onclive.com/view/administration-of-rp1-through-intratumoral-injection-offers-unique-advantages-in-melanoma-treatment

Apr 26th, 2022 - Oncolytic immunotherapy with talimogene laherparepvec (T-VEC; Imlygic) and vusolimogene oderparepvec (RP1) has the potential to provide unique clinical benefits in patients with melanoma through direct intratumoral administration, according to Nik...

How Do We Distinguish Between Viral and Bacterial Meningitis?
https://www.medscape.com/viewarticle/972699

Apr 25th, 2022 - This article was originally published in Portuguese on Medscape . Bacteria and viruses are the leading causes of community-acquired meningitis. Bacterial meningitis is associated with high morbidity and mortality, and prompt treatment with appropr...

Blistering Lesions in a Newborn
https://www.mdedge.com/dermatology/article/253884/pediatrics/blistering-lesions-newborn
Gabriella Alvarez, BS, Shivani Shah, DO, MPH et. al.

Apr 19th, 2022 - The Diagnosis: Epidermolysis Bullosa Our patient was found to have epidermolysis bullosa (EB), a rare genetic disease in which the superficial layers of the skin separate to form vesicles or bullae due to a mutation in the keratin 14 gene, KRT14.

see more →

Patient Education  16 results see all →