ALLMedicine™ Norwalk Virus Center

Apr 28th, 2022 - Study Population Healthy male and female adult volunteers age 18 to 49 years inclusive with blood type O or A and who are confirmed H type-1 antigen secretory positive Investigational Product Active Vaccine: Norovirus GI.1 Norwalk VP1 Vaccine (VXA...

Oct 6th, 2020 - Noroviruses (NoV) are a leading cause of epidemic gastroenteritis. Human challenge studies have been used to examine the infectivity, pathogenicity, and host immune response to NoV as well as vaccine efficacy. The goal of this study was to conduct...

Oct 20th, 2019 - Human noroviruses (HuNoV) are the leading cause of gastroenteritis. No vaccine is currently available to prevent norovirus illness or infection. Safe, infectious challenge strains are needed to assess vaccine efficacy in the controlled human infec...

Jul 26th, 2019 - Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface whil...

Jul 17th, 2018 - History Stool characteristics Diarrhea is defined as daily stools with a mass greater than 15g/kg for children younger than 2 years and greater than 200 g for children 2 years or older. Adult stool patterns vary from 1 stool every 3 days to 3 stoo...

Apr 28th, 2022 - Study Population Healthy male and female adult volunteers age 18 to 49 years inclusive with blood type O or A and who are confirmed H type-1 antigen secretory positive Investigational Product Active Vaccine: Norovirus GI.1 Norwalk VP1 Vaccine (VXA...

Feb 10th, 2012 - Noroviruses are single-stranded, positive-sense RNA viruses that cause acute gastroenteritis in humans. The prototype Norwalk virus (NV) was identified in a large outbreak of acute gastroenteritis in an elementary school in Norwalk, Ohio, in 1968....

Dec 7th, 2011 - An investigational norovirus vaccine was protective against Norwalk virus infection and its associated gastroenteritis in a proof-of-concept study reported in the Dec. 8 issue of the New England Journal of Medicine.

Dec 7th, 2011 - An investigational norovirus vaccine was protective against Norwalk virus infection and its associated gastroenteritis in a proof-of-concept study reported in the Dec. 8 issue of the New England Journal of Medicine.

Dec 7th, 2011 - Action Points Explain that it might be possible to use a vaccine to prevent norovirus illness. Point out that the duration of protection from vaccination is unclear, and the vaccine evaluated in the study protected against the Norwalk strain (geno...

Infection Infectious enteritis is a common cause of acute diarrheal illness in the United States and can be caused by viruses, bacteria, or, less commonly, protozoa. The most common viral causes include norovirus (formerly Norwalk virus) and rotav...