ALLMedicine™ Reoviruses Center

Dec 23rd, 2021 - Segmentation of viral genomes provides the potential for genetic exchange within coinfected cells. However, for this potential to be realized, coinfecting genomes must mix during the viral life cycle. The efficiency of reassortment, in turn, dicta...

Sep 30th, 2021 - Bats are reservoirs of important zoonotic viruses like Nipah and SARS viruses. However, whether the blood-sucking arthropods on the body surface of bats also carry these viruses and the relationship between viruses carried by the blood-sucking art...

Aug 20th, 2021 - Inclusion body hepatitis (IBH) is, in some cases, a fatal disease affecting fowl by adenovirus strains which are subdivided into 5 species (A-E). In the current study, we investigated sequences from the Loop L1 region of the hexon gene of sequence...

Feb 12th, 2021 - Chemotherapy is the main treatment for acute myeloid leukemia (AML), but the therapeutic efficacy is modest, and most commonly manifests as relapse from remission. Thus, improving long-term AML survival is a crucial clinical challenge. In recent y...

Feb 4th, 2021 - Bats are often consumed by some ethnic groups in Nigeria despite association of bats with many important emerging viruses. More than 300 bats representing eight species were captured during 2010-2011 in eight locations of northern Nigeria. Availab...

Oct 12th, 2017 - Oncolytic viruses (OVs) are proving to be a promising modality in anticancer therapy. They selectively grow, replicate within, and kill tumor cells while leaving alone untransformed cells.

Apr 10th, 2017 - Infection with the relatively innocuous reovirus may interfere with tolerance to food antigens and set the stage for — if not directly cause — celiac disease in genetically susceptible individuals, data from mice suggest. The findings, published A...

Apr 10th, 2017 - Infection with the relatively innocuous reovirus may interfere with tolerance to food antigens and set the stage for — if not directly cause — celiac disease in genetically susceptible individuals, data from mice suggest. The findings, published A...

Apr 6th, 2017 - A viral infection may be the culprit behind celiac disease, which is caused by an autoimmune response to dietary gluten. The findings are based on an engineered reovirus, which is normally benign.