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ALLMedicine™ Smallpox Center

Research & Reviews  800 results

Monkeypox Virus Emerges from The Shadow of Its More Infamous Cousin: Family Biology Mat...
https://doi.org/10.1080/22221751.2022.2095309
Emerging Microbes & Infections; Xiang Y, White A

Jun 26th, 2022 - AbstractMonkeypox virus (MPXV) is closely related to the infamous variola (smallpox) virus, causing a febrile rash illness in humans similar to but milder than smallpox. In the 20th century, human monkeypox had been mostly a rare zoonotic disease ...

Monkeypox: considerations for the understanding and containment of the current outbreak...
https://doi.org/10.1007/s11357-022-00611-6 10.1086/425039 10.3201/eid2505.190076 10.3201/eid2604.191164 10.3201/eid2608.191387 10.15585/mmwr.mm7114a1 10.1126/science.295.5562.2001 10.1093/infdis/jiaa559 10.1111/J.1699-0463.1959.TB00328.X 10.3389/fpubh.2018.00241 10.1093/infdis/jiab135 10.1016/j.coviro.2017.11.012 10.1038/nrmicro1099 10.3201/eid2002.130118 10.1128/JVI.66.12.7565-7567.1992 10.1016/s1473-3099(03)00856-9 10.1099/vir.0.81215-0 10.1016/j.tim.2011.12.001 10.1016/S1473-3099(19)30294-4 10.1371/journal.pntd.0010141 10.1016/j.wem.2021.08.003 10.1038/s41564-020-0706-0 10.1002/jmv.25348 10.1016/j.meegid.2019.01.006 10.1016/j.idc.2019.03.001 10.3389/fcimb.2012.00150 10.7589/0090-3558-48.2.335 10.1080/14787210.2020.1735361 10.3201/eid2406.180017 10.3201/eid2206.150579 10.1016/j.jinf.2022.05.028 10.1371/journal.pone.0214229 10.1073/pnas.1005769107 10.1016/j.cell.2012.05.049 10.1093/molbev/msq088 10.1093/bioinformatics/bty407 10.1016/j.virol.2015.03.012 10.1186/1743-422X-3-86 10.1016/j.vaccine.2011.04.014 10.1093/infdis/154.4.551 10.1093/infdis/156.2.293 10.1371/journal.pntd.0007791 10.1093/cid/ciaa143 10.1093/infdis/jix260 10.1016/S1473-3099(22)00228-6 10.1016/0035-9203(85)90333-5 10.3389/fimmu.2011.00021 10.1093/ije/17.3.643
GeroScience Quarleri J, Delpino MV et. al.

Jun 22nd, 2022 - The neglected and rare zoonotic disease caused by monkeypox virus (MPV) has recently spread widely, resulting in the largest known monkeypox outbreak outside of Africa, where it is endemic. MPV belongs to the Poxviridae family, genus Orthopoxvirus...

Monkeypox: What’s a pediatrician to do?
https://www.mdedge.com/pediatrics/article/255506/infectious-diseases/monkeypox-whats-pediatrician-do
Kristina A. Bryant, MD

Jun 16th, 2022 - Not long ago, a pediatrician working in a local urgent care clinic called me about a teenage girl with a pruritic rash. She described vesicles and pustules located primarily on the face and arms with no surrounding cellulitis or other exam finding.

Monkeypox
https://emedicine.medscape.com/article/1134714-overview

Jun 16th, 2022 - Practice Essentials In 1970, when smallpox was nearly eradicated, a previously unrecognized orthopoxvirus named monkeypox was identified in humans. The first known human case occurred in the Equateur province of Zaire (now known as the Democratic ...

Monkeypox
https://emedicine.medscape.com/article/1134714-print

Jun 16th, 2022 - Practice Essentials In 1970, when smallpox was nearly eradicated, a previously unrecognized orthopoxvirus named monkeypox was identified in humans. The first known human case occurred in the Equateur province of Zaire (now known as the Democratic ...

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Guidelines  4 results

Monkeypox - Factsheet
https://www.who.int/news-room/fact-sheets/detail/monkeypox
World Health Organization (WHO)

May 19th, 2022 - Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms similar to those seen in the past in smallpox patients, although it is clinically less severe. With the eradication of smallpox in 1980 and subsequent cessati...

As monkeypox threat grows, scientists debate best vaccine strategy
https://www.science.org/content/article/monkeypox-threat-grows-scientists-debate-best-vaccine-strategy
Science Kupferschmidt K.

May 7th, 2022 - In 1959, German microbiologist Anton Mayr took a strain of vaccinia, a poxvirus used to inoculate against smallpox, and started to grow it in cells taken from chicken embryos. After several years of transferring the strain to fresh cells every few...

Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination
https://pubmed.ncbi.nlm.nih.gov/34185046/
JAMA Cardiology; Kim HW, Jenista ER et. al.

Oct 1st, 2021 - Importance: Vaccine-associated myocarditis is an unusual entity that has been described for the smallpox vaccine, but only anecdotal case reports have been described for other vaccines. Whether COVID-19 vaccination may be linked to the occurrence ...

Monkeypox
https://www.cdc.gov/poxvirus/monkeypox/index.html
Centers for Disease Control and Prevention (CDC)

Monkeypox was first discovered in 1958 when two outbreaks of a pox-like disease occurred in colonies of monkeys kept for research, hence the name ‘monkeypox.’ The first human case of monkeypox was recorded in 1970 in the Democratic Republic of Con...

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Drugs  14 results see all →

Clinicaltrials.gov  91 results

Monkeypox - Factsheet
https://www.who.int/news-room/fact-sheets/detail/monkeypox
World Health Organization (WHO)

May 19th, 2022 - Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms similar to those seen in the past in smallpox patients, although it is clinically less severe. With the eradication of smallpox in 1980 and subsequent cessati...

IMVAMUNE® Smallpox Vaccine in Adult Healthcare Personnel at Risk for Monkeypox in the Democratic Republic of the Congo
https://clinicaltrials.gov/ct2/show/NCT02977715

May 13th, 2022 - Orthopoxvirus infections produce antibody responses that are cross-protective against other viruses within the genus. It is this property of orthopoxviruses that allows a vaccine for vaccinia virus against smallpox to be used to provide protection...

As monkeypox threat grows, scientists debate best vaccine strategy
https://www.science.org/content/article/monkeypox-threat-grows-scientists-debate-best-vaccine-strategy
Science Kupferschmidt K.

May 7th, 2022 - In 1959, German microbiologist Anton Mayr took a strain of vaccinia, a poxvirus used to inoculate against smallpox, and started to grow it in cells taken from chicken embryos. After several years of transferring the strain to fresh cells every few...

OPV as Potential Protection Against COVID-19
https://clinicaltrials.gov/ct2/show/NCT04445428

Mar 18th, 2022 - Since the 1960s, studies have shown that oral polio vaccine (OPV) may have beneficial non-specific effects, reducing morbidity and mortality from other infections than polio. Such beneficial non-specific effect have been observed for other live va...

A Phase 4, Observational Field Study to Evaluate TPOXX in Patients With Smallpox
https://clinicaltrials.gov/ct2/show/NCT03972111

Feb 14th, 2022 - Phase 4, Observational Field Study to evaluate safety and clinical benefit of TPOXX (tecovirimat) in patients treated with TPOXX following exposure to variola virus and a clinical diagnosis of smallpox disease.

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News  223 results

Trending Clinical Topic: Monkeypox
https://www.medscape.com/viewarticle/975896

Jun 24th, 2022 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook.  Although the...

Trending Clinical Topic: Monkeypox
https://reference.medscape.com/viewarticle/975896

Jun 24th, 2022 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook.  Although the...

We Should Vaccinate Gay and Bisexual Men for Monkeypox Now
https://www.medscape.com/viewarticle/976100

Jun 23rd, 2022 - I previously reported on the history of the current outbreak of monkeypox among mainly men who have sex with men (MSM) in this Medscape blog. As we discussed, there is a large monkeypox outbreak going on across the United Kingdom, Europe, Australi...

Africa Officials Urge Readiness for Monkeypox Vaccinations, Fair Access
https://www.medscape.com/viewarticle/975714

Jun 17th, 2022 - DAKAR (Reuters) - The World Health Organization is procuring thousands of monkeypox tests for Africa and working to ensure the continent has fair access to vaccines should the need arise, WHO Africa Director Matshidiso Moeti said on Thursday. Monk...

Monkeypox: What’s a pediatrician to do?
https://www.mdedge.com/pediatrics/article/255506/infectious-diseases/monkeypox-whats-pediatrician-do
Kristina A. Bryant, MD

Jun 16th, 2022 - Not long ago, a pediatrician working in a local urgent care clinic called me about a teenage girl with a pruritic rash. She described vesicles and pustules located primarily on the face and arms with no surrounding cellulitis or other exam finding.

see more →

Patient Education  7 results see all →