JAMA Oncology; Calkins KL, et al
Dec 4th, 2019 - What is the association between cancer treatment and CD4 count and HIV RNA level, and how are these markers associated with all-cause mortality among people with HIV?
New England Journal of Medicine; David M. Morens, M.D. et. al.
Nov 24th, 2019 - Humans have always lived in intimate association with arthropods that transmit pathogens between humans or from animals to humans. About 700,000 deaths due to vectorborne diseases occur globally each year, according to World Health Organization estimates. In the summer and fall of 2019, nine U.S. states have reported 36 human cases (14 of them fatal) of one of the deadliest of these diseases: e...
American Journal of Respiratory and Critical Care Medicine; Payam Nahid et al
Nov 20th, 2019 - The American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory Society, and Infectious Diseases Society of America jointly sponsored this new practice guideline on the treatment of drug-resistant tuberculosis (DR-TB). The document includes recommendations on the treatment of multidrug-resistant TB (MDR-TB) as well as isoniazid-resistant but rifampin-suscept...
JAMA Wald A
Nov 16th, 2019 - Chronic constipation is very common. The most recent estimate of clinician visits attributable to constipation were from 2001 to 2004 and reported more than 8 million clinician visits in the United States, with most occurring in adult primary care settings (33%) followed by pediatric (21%) and gastroenterologist (14%) offices.1 These encounters result in large expenditures for nonprescription l...
Nov 16th, 2019 - Summary of Recommendation and Evidence The USPSTF recommends that clinicians offer preexposure prophylaxis (PrEP) with effective antiretroviral therapy to persons who are at high risk of HIV acquisition (Table 1). A recommendation.
Nov 14th, 2019 - CDC’s Antibiotic Resistance Threats in the United States, 2019 (2019 AR Threats Report) includes the latest national death and infection estimates that underscore the continued threat of antibiotic resistance in the U.S. According to the report, more than 2.8 million antibiotic-resistant infections occur in the U.S. each year, and more than 35,000 people die as a result. In addition, 223,900...
HIV Medicine; Brusca RM, et al
Nov 13th, 2019 - Elite controllers (ECs), viraemic controllers (VCs), and long‐term nonprogressors (LTNPs) control HIV viral replication or maintain CD4 T‐cell counts without antiretroviral therapy, but may have increased cardiovascular disease (CVD) risk compared to HIV‐uninfected persons. We evaluated subclinical carotid and coronary atherosclerosis and inflammatory biomarker levels among HIV controllers, LTN...
HLA Bjorkman PJ
Nov 11th, 2019 - HIV/AIDS remains one of the most important current threats to global public health. Since its identification in the early 1980s, at least 75 million people have been infected with HIV‐1, the virus that causes AIDS. Although anti‐retroviral drugs are effective at prolonging life after infection in the developed world, they are associated with significant side effects and are not in widespread us...
Nov 5th, 2019 - The U.S. Food and Drug Administration (FDA) has approved a supplemental Biologics License Application for Fluzone® High-Dose Quadrivalent (Influenza Vaccine) for use in adults 65 years of age and older. Fluzone® High-Dose (Influenza Vaccine) was approved by the FDA in 2009 as a trivalent influenza vaccine, including two influenza A strains and one influenza B strain. Fluzone High-Dose Quadri...
The New England Journal of Medicine; Tait, D. et. al.
Oct 28th, 2019 - BACKGROUND Results of an earlier analysis of a trial of the M72/AS01E candidate vaccine against Mycobacterium tuberculosis showed that in infected adults, the vaccine provided 54.0% protection against active pulmonary tuberculosis disease, without evident safety concerns. We now report the results of the 3-year final analysis of efficacy, safety, and immunogenicity. METHODS From August 201...
Oct 28th, 2019 - Selected risk factors (things that increase your chance of getting cancer), including tobacco and alcohol use and human papillomavirus (HPV).
Oct 28th, 2019 - Shingles (also known as herpes zoster) results from infection by the varicella zoster virus. This common virus causes chickenpox (also known as varicella), which is characterized by itchy spots on the skin that cover the whole body and usually occurs in childhood or adolescence. After the body fights the initial infection, the varicella zoster virus remains in nerve cells for the rest of a per...
Nature Medicine; Schubert, R. et. al.
Oct 20th, 2019 - Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1,2,3,4,5,6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal fluid (CSF)2. CSF from children with AFM (n = 42) and other pediatric neurologic disease controls (n = 58) were investigated for intra...
Oct 16th, 2019 - Single-dose Xofluza is the first and only antiviral medicine indicated specifically for patients at high risk of developing serious complications from influenza (flu) The Centers for Disease Control and Prevention (CDC) defines people at high risk of serious flu complications as those who have conditions such as asthma, chronic lung disease, diabetes, heart disease, morbid obesity or adults ...
Oct 14th, 2019 - The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) has released its recommendations for routine influenza vaccination in the 2019–2020 season. Updates this year include the antigenic composition of seasonal influenza vaccines available in the United States and changes related to recent regulatory actions, including labeling changes for previousl...
American Family Physician;
Oct 14th, 2019 - A seven-year-old boy presented with abnormal growth of his fingernails that began two weeks prior. He had no other symptoms, including pain or pruritus on his hands or around his nails. He did not have fevers, chills, nausea, vomiting, or change in activity. He had hand-foot-and-mouth disease two months earlier that was diagnosed based on vesicular lesions in his mouth and on his hands and feet...
Oct 7th, 2019 - Data released this week by the Centers for Disease Control and Prevention (CDC) show STDs have surged for the fifth consecutive year, reaching an all-time high in the U.S. These dangerous trends in chlamydia, gonorrhea, and syphilis show no sign of slowing and affect millions of lives each year in the United States. Particularly worrisome is the emerging trend of newborn syphilis (congenital sy...
Oct 6th, 2019 - Pharmacists in California will be able to dispense HIV prevention pills to patients without a doctor’s prescription after Gov. Gavin Newsom signed legislation Monday that supporters say will greatly reduce the spread of infection. Advocates of Senate Bill 159 say California is the first state to authorize pre-exposure prophylaxis, also called PrEP, and post-exposure prophylaxis, known as PEP...
Morbidity and Mortality Weekly Report; Patel, M. et. al.
Oct 3rd, 2019 - What is already known about this topic? Measles was eliminated in the United States in 2000. High national coverage with measles, mumps, and rubella vaccine and rapid implementation of measles control measures prevent widespread measles transmission. What is added by this report? During January–September 2019, 1,249 U.S. measles cases were reported, the highest annual number since 1992...
Oct 2nd, 2019 - CDC Centers for Disease Control and Prevention Influenza Flu - vaccination resources for healh care professionals includes links to ACIP resources, flu vaccine information and patient education materials.
American Family Physician; Saguil, A. et. al.
Sep 30th, 2019 - Hand-foot-and-mouth disease is caused by human enteroviruses and coxsackieviruses. Outbreaks can occur in the spring to fall and are common in North America, and most cases occur in patients younger than 10 years. Hand-foot-and-mouth disease is transmitted by fecal-oral, oral-oral, and respiratory droplet contact. Patients present with a low-grade fever, a maculopapular or papulovesicular rash ...
American Family Physician; Coffa, D. et. al.
Sep 30th, 2019 - Opioid use disorder is highly prevalent and can be fatal. At least 2.1 million Americans 12 years and older had opioid use disorder in 2016, and approximately 47,000 Americans died from opioid overdoses in 2017. Opioid use disorder is a chronic relapsing condition, the treatment of which falls within the scope of practice of family physicians. With appropriate medication-assisted treatment, pat...
American Family Physician;
Sep 30th, 2019 - “Virtually every issue [that] relates to drug dependence is suffused with emotion that turns differences of opinion into controversy and leads to distortions, exaggerations, and misunderstandings.” This quotation comes from 1971 in the early days of methadone treatment. Policy makers and practitioners were wrestling with a strategy to safely use this effective medication. We are now faced wi...
Antioxidants (Basel); Rugemalira E, et al
Sep 30th, 2019 - The immunological response in bacterial meningitis (BM) causes the formation of reactive oxygen and nitrogen species (ROS, RNS) and activates myeloperoxidase (MPO), an inflammatory enzyme. Thus, structural oxidative and nitrosative damage to proteins and DNA occurs. We aimed to asses these events in the cerebrospinal fluid (CSF) of pediatric BM patients.
Sep 27th, 2019 - An ongoing dialogue on HIV/AIDS, infectious diseases, all matters medical, and some not so medical.
Sep 24th, 2019 - Abbott (NYSE: ABT) today announced that its ARCHITECT STAT High Sensitivity Troponin-I blood test has received clearance from the U.S. Food and Drug Administration (FDA). As one of the most researched troponin diagnostic tests, doctors in the U.S. can now utilize this proven technology to help detect heart attacks faster and more accurately than contemporary troponin tests.
Sep 23rd, 2019 - Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is an extensive update of KDIGO's 2008 guideline on HCV infection in CKD. This update reflects the major advances since the introduction of direct-acting antivirals (DAAs...
Sep 17th, 2019 - An alarming number of people nationwide are developing infections of either the heart’s inner lining or valves, known as infective endocarditis, in large part, due to the current opioid epidemic. This new trend predominantly affects young, white, poor men who also have higher rates of HIV, hepatitis C and alcohol abuse, according to new research published in the Journal of the American Heart As...
Sep 17th, 2019 - Nearly half of people in the United States living with diagnosed HIV are aged 50 and older. Though new HIV diagnoses are declining among people aged 50 and older, around 1 in 6 HIV diagnoses in 2016 were in this group.
Sep 15th, 2019 - What you need to know about the upcoming 2019-2020 influenza season in the United States.
The Lancet Infectious Diseases;
Sep 9th, 2019 - Historically, the human pathogen Streptococcus pyogenes (group A streptococcus) was a major cause of death as a result of sepsis and fatal epidemics of scarlet fever.1 Despite a decline in the incidence and severity of these toxin-mediated diseases over the past century in high-income countries, group A streptococcus is still among the top ten infectious causes of human mortality, with more tha...
Sep 9th, 2019 - Since 2014, England has seen increased scarlet fever activity unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected elevation in invasive Streptococcus pyogenes infections. We describe the molecular epidemiological investigation of these events.
Aug 28th, 2019 - The pages listed below offer public health and health care professionals key information about vaccination, infection control, prevention, treatment, and diagnosis of seasonal influenza.
Aug 27th, 2019 - The Food and Drug Administration (FDA) has received reports that the use of Mavyret, Zepatier, or Vosevi to treat chronic hepatitis C in patients with moderate to severe liver impairment has resulted in rare cases of worsening liver function or liver failure. All these medicines contain a hepatitis C virus (HCV) protease inhibitor and are not indicated for use in patients with moderate to sever...
Aug 25th, 2019 - 2018 - 2019 Measles Outbreak in Rockland County: As of August 26, 2019, there are 312* confirmed reported cases of measles in Rockland County. *On Monday, August 26, 2019, 16 historical cases of measles were added to the current total. These cases occurred between early February 2019 and mid-May 2019.
Aug 21st, 2019 - A chart of recommended available 2016-17 influenza vaccines by type and manufacturer - CDC
American Family Physician;
Aug 14th, 2019 - Patient story about being diagnosed with hepatitis C and successful treatment by family doctor.
Aug 11th, 2019 - The U.S. Food and Drug Administration is warning consumers not to purchase or drink a product sold online as a medical treatment due to a recent rise in reported health issues. Since 2010, the FDA has warnedExternal Link Disclaimer consumers about the dangers of Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide (CD) Protocol, Water Purification Solution (WPS)...
American Family Physician;
Jul 31st, 2019 - Clinical Question Do influenza vaccines reduce the risk of influenza in healthy children, healthy adults, and older adults? Evidence-Based Answer Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absentee...
Jul 31st, 2019 - We investigated an outbreak of listeriosis detected by whole-genome multilocus sequence typing and associated with packaged leafy green salads. Nineteen cases were identified in the United States during July 5, 2015–January 31, 2016; isolates from case-patients were closely related (median difference 3 alleles, range 0–16 alleles). Of 16 case-patients interviewed, all reported salad consumption...
Annals of Internal Medicine;
Jul 29th, 2019 - Background: Prior studies evaluating risk for severe urinary tract infections (UTIs) with sodium–glucose cotransporter-2 (SGLT-2) inhibitors have reported conflicting findings. Objective: To assess whether patients initiating use of SGLT-2 inhibitors were at increased risk for severe UTI events compared with those initiating use of dipeptidyl peptidase-4 (DPP-4) inhibitors or glucagon-like...
American Family Physician;
Jul 28th, 2019 - Measles is one of the most highly transmissible diseases, with 90% of unvaccinated persons infected after contact.1 In 2000, the Centers for Disease Control and Prevention (CDC) declared that measles was eliminated in the United States, but that elimination status may be revoked if the current chain of measles transmission and outbreaks continues for one year, through the fall of 2019. As ...
Jul 22nd, 2019 - Screening for hepatitis B virus (HBV) infection during pregnancy identifies women whose infants are at risk of perinatal transmission. Data from a nationally representative sample showed a prevalence of maternal HBV infection of 85.8 cases per 100 000 deliveries from 1998 to 2011 (0.09% of live-born singleton deliveries in the United States). Although there are guidelines for universal infant H...
Jul 22nd, 2019 - Contemporary clinicians who provide obstetric care acknowledge screening of pregnant women for perinatally transmissible infectious diseases as a routine component of prenatal care,1 although this has not always been the case. For example, prenatal screening for hepatitis B virus (HBV) infection only began to be discussed after rigorous trials conducted in the 1970s and 1980s in high-endemic ar...
Jul 17th, 2019 - Measles is one of the most easily transmitted viruses known to man. It spreads via the respiratory system – much like influenza and TB. An infected person coughs the virus and others inhale it. The measles virus remains infectious in the air up to two hours after the infectious individual has left the area.
Jul 16th, 2019 - Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved RECARBRIO™ (imipenem, cilastatin, and relebactam) for injection, 1.25 grams, a new combination antibacterial. RECARBRIO is indicated in patients 18 years of age and older who have limited or no alternative treatment options, for the treatment of comp...
Jul 15th, 2019 - This is an update of the ASRM Zika virus guidance for providers that addresses the care of non-pregnant patients desiring pregnancy, originally released in September 2016 and updated in August 2018. This revised document reflects the changes that the CDC has made on its Blood and Tissue Safety webpage to more clearly communicate epidemiological information about the risk of Zika virus infect...
Jul 15th, 2019 - The diagnostic challenges in patients with clinical findings of meningitis are as follows: Early identification and treatment of patients with acute bacterial meningitis Assessing whether a treatable central nervous system (CNS) infection is present in those with suspected subacute or chronic meningitis Identifying the causative organism
Jul 9th, 2019 - Eastern Equine Encephalitis is a rare disease that is caused by a virus spread by infected mosquitoes
Jul 1st, 2019 - Shingles resources and references include Shingrix and Zostavax vaccination recommendations, as well as disease- and vaccine-related resources and articles.
Jun 30th, 2019 - Human immunodeficiency virus (HIV) infection should be considered in any patient with unusual or recurrent serious infections without another cause, especially in those with risk factors for HIV infection.
Jun 30th, 2019 - This page provides information on the estimated per-act probability of acquiring HIV from an infected source.
Jun 30th, 2019 - Learn more about shingles surveillance, including shingles hospitalizations, trends, and vaccination rates
Jun 30th, 2019 - Learn about varicella zoster virus (VZV) laboratory testing and about the CDC National VDZ Laboratory.
Jun 30th, 2019 - Doxycycline is an antibiotic used to treat bacterial infections like urinary tract infections, acne and chlamydia. Includes side effects, interactions and indications.
Jun 30th, 2019 - Screening for human immunodeficiency virus (HIV) infection is paramount, since infected individuals may remain asymptomatic for years while the infection progresses. Serologic tests are the most important studies in the evaluation for HIV infection.
Jun 26th, 2019 - Schizophrenia is a severe mental illness with important implications for morbidity and mortality. This population-based cohort study examined the impact of schizophrenia diagnoses on all-cause mortality among a sample of people living with HIV (PLHIV) and a 10% random sample of individuals living without HIV (HIV-) in British Columbia (BC), through a data linkage between the BC Centre for Excel...
Jun 26th, 2019 - People with HIV infection are affected disproportionally by viral hepatitis. Nearly 75% of people with HIV who report a history of injection drug use also are infected with hepatitis C virus (HCV).
Jun 26th, 2019 - The Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR) are now accepting comments on the “2019 Draft Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease.” We are looking for feedback from not only physicians and healthcare professionals, but also individuals affected by Lyme disease, such as patients,...
Jun 12th, 2019 - In people with HIV, good nutrition supports overall health and helps maintain the immune system. Good nutrition also helps people with HIV maintain a healthy weight and absorb HIV medicines.
JAMA US Preventive Services Task Force
Jun 10th, 2019 - Importance Approximately 1.1 million persons in the United States are currently living with HIV, and more than 700 000 persons have died of AIDS since the first cases were reported in 1981. There were approximately 38 300 new diagnoses of HIV infection in 2017. The estimated prevalence of HIV infection among persons 13 years and older in the United States is 0.4%, and data from the Centers for...
JAMA US Preventive Services Task Force
Jun 10th, 2019 - Importance Effective prevention strategies for HIV infection are an important public health priority. Preexposure prophylaxis (PrEP) involves use of antiretroviral therapy (ART) daily or before and after sex to decrease risk of acquiring HIV infection. Objective To synthesize the evidence on the benefits and harms of PrEP, instruments for predicting incident HIV infection, and PrEP adheren...
JAMA US Preventive Services Task Force
Jun 10th, 2019 - Importance Untreated HIV infection can result in significant morbidity, mortality, and HIV transmission. A 2012 review for the US Preventive Services Task Force (USPSTF) found antiretroviral therapy (ART) associated with improved clinical outcomes and decreased transmission risk in persons with CD4 cell counts less than 500/mm3. Objective To update the 2012 review on HIV screening to infor...
JAMA US Preventive Services Task Force
Jun 10th, 2019 - Objective To update the 2012 review on prenatal HIV screening to inform the USPSTF. Data Sources Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews from 2012 to June 2018, with surveillance through January 2019. Study Selection Pregnant persons 13 years and older; randomized clinical trials and cohort studies of screening v...
JAMA US Preventive Services Task Force
Jun 10th, 2019 - Importance An estimated 1.1 million individuals in the United States are currently living with HIV, and more than 700 000 persons have died of AIDS since the first cases were reported in 1981. In 2017, there were 38 281 new diagnoses of HIV infection reported in the United States; 81% of these new diagnoses were among males and 19% were among females. Although treatable, HIV infection has no c...
May 31st, 2019 - 1 in 5 U.S. teens have not yet received their first dose of the meningococcal vaccine against serogroups A, C, W and Y and remain unprotected.
May 29th, 2019 - Today, CDC is reporting 971 cases of measles in the United States thus far in 2019. This is the greatest number of cases reported in the U.S. since 1994, when 963 cases were reported for the entire year. CDC continues to work with affected state and local health departments to get ongoing outbreaks under control.
The Cochrane Database of Systematic Reviews; Threapleton, C. et. al.
May 23rd, 2019 - Chronic obstructive pulmonary disease (COPD; including chronic bronchitis and emphysema) is a chronic respiratory condition characterised by shortness of breath, cough and recurrent exacerbations. Long‐term antibiotic use may reduce both bacterial load and inflammation in the airways. Studies have shown a reduction of exacerbations with antibiotics in comparison to placebo in people with COPD, ...
May 18th, 2019 - Vaccines and immunization Licensed vaccines against meningococcal disease have been available for more than 40 years. Over time, there have been major improvements in strain coverage and vaccine availability, but to date no universal vaccine against meningococcal disease exists. Vaccines are serogroup specific and confer varying degrees of duration of protection. There are three types of menin...
May 8th, 2019 - Safety Review of DEET (chemical name, N,N-diethyl-meta-toluamide) is the active ingredient in many repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, an estimated one-third of the U.S. population use DEET to protect them from mosquito-borne illnesses like West Nile Virus, the Zika virus or malaria and tick-borne illnesses like Lyme disease and ...
Apr 30th, 2019 - Over the past few decades, our ability to diagnose, treat, and manage recurrent urinary tract infection (rUTI) long-term has evolved due to additional insights into the pathophysiology of rUTI, a new appreciation for the adverse effects of repetitive antimicrobial therapy (“collateral damage”), rising rates of bacterial antimicrobial resistance, and better reporting of the natural history and c...
Apr 30th, 2019 - Antimicrobial prophylaxis for the prevention of Lyme disease (Table 1) following tick bite may be beneficial in certain circumstances. A single dose of doxycycline can lower the risk of Lyme disease when: The tick bite occurred in a state where Lyme disease incidence is high
Apr 25th, 2019 - The United States is currently experiencing the greatest number of reported cases of measles, also known as rubeola, since the disease was eliminated in 20001. Outbreaks have been confirmed in 22 states and the number of cases and their distribution is increasing rapidly. These measles outbreaks have been linked to travelers bringing back cases of measles from other countries. This situation co...
Apr 18th, 2019 - CDC provides leadership for HIV prevention research and surveillance and the development and testing of effective biomedical interventions to reduce transmission and HIV disease progression in the United States and internationally. It also provides national leadership in the development, implementation, and evaluation of evidence-based HIV prevention programs serving persons affected by, or at ...
Apr 17th, 2019 - Welcome to DPDx, a website developed and maintained by CDC’s Division of Parasitic Diseases and Malaria (DPDM). DPDx uses the Internet to strengthen diagnosis of parasitic diseases, both in the United States and abroad. This interactive and rapid exchange of information, allied with already available diagnostic reference resources, will enhance our capacity to address the global problem of para...
Apr 15th, 2019 - A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Botulism
Apr 14th, 2019 - Measles, Also Known As Rubeola, Is A Highly Contagious Airborne Viral Illness That Infects Approximately Nine Out Of Ten Exposed Susceptible Individuals. Measles Infection Was Common Until The Measles, Mumps, And Rubella (MMR) Vaccine Was Licensed In 1963 And Became Part Of The Routine Immunization Schedule. By 2000, Measles Was Essentially Eliminated From The United States. In The Last Decade,...
Apr 8th, 2019 - What are the case definitions for reportable hepatitis C virus (HCV) infections? The specific viral cause of illness cannot be determined based solely on signs, symptoms, history, or current risk factors, but must be verified by specific serologic testing
Apr 4th, 2019 - Serogroup B Meningococcal (MenB) Vaccine Information Statement Meningococcal disease is a serious illness caused by a type of bacteria called Neisseria meningitidis. It can lead to meningitis (infection of the lining of the brain and spinal cord) and infections of the blood. Meningococcal disease often occurs without warning – even among people who are otherwise healthy.
Apr 4th, 2019 - Learn about HIV infection and AIDS and the laboratory tests used to screen for HIV, help diagnose HIV, and select and monitor HIV treatment. HIV (human immunodeficiency virus) is the virus that causes AIDS (acquired immunodeficiency syndrome). HIV progressively destroys the body's ability to fight infections and certain cancers. It weakens the immune system by infecting lymphocytes, a type of w...
Apr 3rd, 2019 - Education and information about the brain eating ameba Naegleria fowleri that causes encephalitis and death including frequently asked questions, biology, sources of infection, diagnosis, treatment, prevention and control, and other publications and pertinent information for the public and medical professionals
Mar 31st, 2019 - Measles Cases in 2019 From January 1 to February 21, 2019, 159** individual cases of measles have been confirmed in 10 states. In a given year, more measles cases can occur for any of the following reasons: an increase in the number of travelers who get measles abroad and bring it into the U.S., and/or further spread of measles in U.S. communities with pockets of unvaccinated people.
Mar 31st, 2019 - A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Dengue fever
Benson, A. et. al.
Mar 31st, 2019 - Incidence and mortality rates for cancer overall are declining, but both incidence and mortality rates for hepatocellular carcinoma (HCC) are increasing.1,2 Risk factors for development of HCC include infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV), and cirrhosis of the liver (eg, alcohol cirrhosis).3 Metabolic disorders (ie, obesity, diabetes, impaired glucose metabolism,...
Mar 27th, 2019 - CDC is issuing new guidance to clinicians for the treatment of severe malaria cases in the United States (U.S.). This change in treatment protocol is necessary because the only FDA-approved intravenous (IV) antimalarial drug in the U.S., quinidine, has been discontinued by the manufacturer and will no longer be available. As of April 2019, artesunate, the WHO-recommended first-line treatment o...
Mar 24th, 2019 - Multiple states across the country have reported outbreaks of hepatitis A, primarily among people who use drugs and people experiencing homelessness. Since the hepatitis A outbreaks were first identified in 2016, more than 15,000 cases, 8,500 (57%) hospitalizations, and 140 deaths as a result of hepatitis A virus (HAV) infection have been reported. This Health Alert Network (HAN) update recomme...
Mar 23rd, 2019 - H1N1 Swine flu is a subtype of influenza A virus (a communicable viral disease), which causes upper, and potentially, lower respiratory tract infections in the host it infects, resulting in symptoms such as nasal secretions, chills, fever, decreased appetite, and possibly lower respiratory tract disease. H1N1 swine influenza is a common infection in pigs worldwide, and that is why it is also kn...
Mar 22nd, 2019 - Weekly U.S. Influenza Surveillance Report: FluView - CDC
Mar 14th, 2019 - The risk for getting HIV is very high if an HIV-negative person uses needles, syringes, or other injection equipment that someone with HIV has used. Estimated annual HIV infections among people who inject drugs (PWID) declined 32% from 2010 to 2014 in the United States.a However, injection drug use in nonurban areas has created prevention challenges and has placed new populations at risk for HIV.
Mar 13th, 2019 - The American Academy of Pediatrics (AAP) will advise families to vaccinate their children against influenza next season with either the flu shot or the nasal spray vaccine for the best protection against the virus during the 2019-2020 flu season. The recommendation differs slightly from last year, when AAP cited a preference for the injected vaccine over the nasal spray - except in cases whe...
Current Rheumatology Reports; Doaty, S. et. al.
Mar 6th, 2019 - Infection is a leading cause of morbidity and mortality among patients with systemic lupus erythematous (SLE). Dysfunction of the innate and adaptive immune systems increases the risk of infection in patients with SLE. Infectious agents have also been theorized to play a role in the pathogenesis of SLE. This article summarizes our current knowledge of the infectious risk SLE patients face as a ...
Mar 5th, 2019 - Measles, also known as rubeola, is a preventable, highly contagious, acute febrile viral illness. It remains an important cause of global mortality and morbidity, particularly in the regions of Africa and Southeast Asia
Mar 1st, 2019 - The FDA has approved a new drug application for Avaclyr, Fera Pharmaceuticals’ herpetic keratitis treatment, according to a press release. Avaclyr (acyclovir ophthalmic ointment 3%), a herpes simplex virus nucleoside analog DNA polymerase inhibitor, is indicated to treat dendritic ulcers in patients with HSV-1 and HSV-2, the release said.
Feb 28th, 2019 - Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult to treat than drug-susceptible ones, and threaten global progress towards the targets set by the End TB Strategy of the World Health Organization (WHO). There is thus a critical need for evidence-based policy recommendations on the treatment and care of patients with DR-TB, based on the most recent and comprehensive evide...
Feb 27th, 2019 - Proper vaccine storage and handling practices play a very important role in protecting individuals and communities from vaccine-preventable diseases.Vaccine quality is the shared responsibility of everyone, from the time vaccine is manufactured until it is administered.
Feb 27th, 2019 - The Guidelines for malaria vector control provide a “one-stop shop” for all countries and partners working to implement effective malaria vector control measures. They cover the 2 core malaria vector control interventions – ITNs and IRS – as well as supplementary interventions, namely chemical and biological larvicides, and personal protection measures, such as the use of topical repellents. ...
Feb 27th, 2019 - Overview of tetanus for clinicians including pathogenesis, symptoms, diagnosis, treatment, prevention and complications.
Feb 21st, 2019 - Currently there is only one home HIV test available in the United States, the OraQuick In-home HIV test. If you buy any home test online make sure the HIV test is FDA-approved. The OraQuick In-Home HIV Test provides rapid results in the home. The testing procedure involves swabbing your mouth for an oral fluid sample and using a kit to test it. Results are available in 20 minutes. If you tes...
Feb 20th, 2019 - WHO convenes technical consultations in February and September each year to recommend viruses for inclusion in influenza vaccines for the northern and southern hemisphere influenza seasons, respectively. This recommendation relates to the influenza vaccines for use in the forthcoming northern hemisphere 2019-2020 influenza season. A recommendation will be made in September 2019 relating to...
Feb 20th, 2019 - The human immunodeficiency virus (HIV) is an enveloped retrovirus that contains 2 copies of a single-stranded RNA genome. It causes the acquired immunodeficiency syndrome (AIDS) that is the last stage of HIV disease. Four to 10 weeks after the HIV enters the body, the patient may complain of symptoms of primary infection