About 14,423 results

ALLMedicine™ Hypercholesterolemia Center

Research & Reviews  3,809 results

Conservative management of the colonic gallstone.
BMJ Case Reports; Hurst KV, Peiris GB et. al.

Dec 2nd, 2021 - A 74-year-old woman presents with a 7-day history of increasing lower abdominal pains and reduced bowel movements; resulting in absolute constipation.Twenty-four hours prior to admission she also had symptoms of nauseous and significant abdominal ...

Normal weight obesity is associated with hypercholesterolemia and low muscle mass in pe...
Nutrition (Burbank, Los Angeles County, Calif.); Osuna-Padilla IA, Rodríguez-Moguel NC et. al.

Nov 30th, 2021 - Normal weight obesity (NWO) is defined as a condition of normal body weight, but with high body fat percentage. Clinical and immunologic implications of NWO in persons living with HIV (PLHIV) remain unknown. The aim of this study was to examine NW...

An update on emerging drugs for the treatment of hypercholesterolemia.
Expert Opinion on Emerging Drugs; Nelson AJ, Bubb K et. al.

Nov 30th, 2021 - Elevated levels of low-density lipoprotein (LDL) cholesterol have been unequivocally demonstrated to play a causal role in atherosclerotic cardiovascular disease. The last thirty years has witnessed a generation of clinical trials that have demons...

Applying implementation science to improve care for familial hypercholesterolemia.
Current Opinion in Endocrinology, Diabetes, and Obesity; Jones LK, Brownson RC et. al.

Nov 29th, 2021 - Improving care of individuals with familial hypercholesteremia (FH) is reliant on the synthesis of evidence-based guidelines and their subsequent implementation into clinical care. This review describes implementation strategies, defined as method...

Statins: a panacea to reduce mortality in patients undergoing liver transplantation for...
Liver Transplantation : Official Publication of the Ameri... Shawcross DL, Suddle A

Nov 28th, 2021 - In Greek mythology Panacea was the goddess of universal remedy or health. In literary terms a panacea represents a solution to solve all ills and there are few drugs that can claim such an accolade. One drug class that has claimed to be a panacea ...

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Guidelines  6 results

The 2021 European Group on Graves' orbitopathy (EUGOGO) clinical practice guidelines fo...
European Journal of Endocrinology; Bartalena L, Kahaly GJ et. al.

Jul 24th, 2021 - Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease (GD). Choice of treatment should be based on the assessment of clinical activity and severity of GO. Early referral to specialized centers is fundamental for most...

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Up...
The Canadian Journal of Cardiology; Brunham LR, Ruel I et. al.

Dec 12th, 2018 - Familial hypercholesterolemia (FH) is the most common monogenic disorder causing premature atherosclerotic cardiovascular disease. It affects 1 in 250 individuals worldwide, and of the approximately 145,000 Canadians estimated to have FH, most are...

Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" ...
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Pirro M, Vetrani C et. al.

Dec 14th, 2016 - Evidence showed that LDL-cholesterol lowering is associated with a significant cardiovascular risk reduction. The initial therapeutic approach to hypercholesterolemia includes dietary modifications but the compliance to recommendations is often in...

Screening for Abdominal Aortic Aneurysm: Clinical Summary of USPSTF Recommendation

Jun 17th, 2014 - SCREENING FOR ABDOMINAL AORTIC ANEURYSM CLINICAL SUMMARY OF U.S. PREVENTIVE SERVICES TASK FORCE RECOMMENDATION Population Men ages 65 to 75 years who have ever smoked* Men ages 65 to 75 years who have never smoked Women ages 65 t...

Screening for Cognitive Impairment in Older Adults: Clinical Summary of USPSTF Recommendation

Mar 18th, 2014 - SCREENING FOR COGNITIVE IMPAIRMENT IN OLDER ADULTS CLINICAL SUMMARY OF U.S. PREVENTIVE SERVICES TASK FORCE RECOMMENDATION Population Community-dwelling adults who are older than age 65 years and have no signs or symptoms of cognitive impa...

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Drugs  937 results see all →

Clinicaltrials.gov  223 results

Study to Assess the Real World Effectiveness of Inclisiran in Chinese Adult Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Nov 17th, 2021 - This study will utilize real-world data from EMR database to serve as the 'external control'.The purpose of this study is to compare the effectiveness of inclisiran as an add-on therapy (or monotherapy in statin-intolerant cases) in real-world set...

Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions

Nov 16th, 2021 - Hypertension and physical inactivity are the most common risk factors for stroke. Patients with minor stroke or transient ischemic attack (TIA) have short-lasting symptoms, often with remission within hours or days. Though patients experience a qu...

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Nov 12th, 2021 - Familial hypercholesterolemia is an autosomal co-dominant disorder resulting in abnormal LDL receptor function, profoundly elevated concentrations of low density lipoproteins, accelerated atherosclerosis and death by early adulthood. This disease ...

Prognostic Factors in Patients With STEMI Treated by pPCI

Nov 2nd, 2021 - Currently, primary percutaneous coronary intervention is the first choice for patients with acute ST-segment elevation myocardial infarction. In the past 40 years, the development of rapid reperfusion therapy has gradually reduced the mortality ra...

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Oct 19th, 2021 - This is a two-part (1 year double-blind inclisiran versus placebo / 1 year open-label inclisiran) multicenter study designed to evaluate safety, tolerability, and efficacy of inclisiran in adolescents with homozygous familial hypercholesterolemia ...

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News  788 results

Evaluation of the Effectiveness and Safety of Alirocumab Use in Statin-Intolerant Veterans
Fiona I. Imarhia, PharmD, BCPS, Elisabeth M. Sulaica, PharmD, BCCP et. al.

Nov 10th, 2021 - In 2016, 17. 6 million deaths occurred globally due to cardiovascular disease (CVD) with coronary artery disease (CAD) and ischemic stroke as top contributors.

Familial Hypercholesterolemia — Hiding in Plain Sight

Oct 21st, 2021 - This transcript has been edited for clarity. Laurence Sperling, MD: Welcome to the Medscape InDiscussion podcast series on dyslipidemia. This is the first of six episodes. To launch this series today, we will focus on an extremely important topic:...

Failed Studies Provide Clues in Renal Cell Carcinoma

Oct 6th, 2021 - Brian Rini, MD The mTOR inhibitor temsirolimus has limited utility in combination with frontline bevacizumab and as a second-line single agent for patients with metastatic renal cell carcinoma (mRCC), according to two recently published articles ...

Adding Statins to Steroids in Thyroid Eye Disease Improves Outcomes

Oct 4th, 2021 - Treatment of Graves' orbitopathy with statins in combination with glucocorticoids shows benefits among people with — and even without — high cholesterol, results from a new randomized clinical trial show. "Our results [indicate] that adding atorva...

Familial Hypercholesterolemia Diagnosed Late, LDL Control Far Below Recommendations

Sep 30th, 2021 - NEW YORK (Reuters Health) - Globally, familial hypercholesterolemia (FH) is diagnosed late, and control of LDL cholesterol in patients is far below recommendations, a new analysis shows. "Guideline-recommended LDL cholesterol concentrations are in...

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Patient Education  6 results see all →