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About 254,414 results

ALLMedicine™ Type 2 Diabetes Center

Research & Reviews  116,073 results

Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Dia...
https://doi.org/10.1016/j.amjms.2020.10.027
The American Journal of the Medical Sciences; Zhou J, Effiong U

May 7th, 2021 - Pyridoxine is an important co-factor for many biochemical reactions in cellular metabolism related to the synthesis and catabolism of amino acids, fatty acids, neurotransmitters. Deficiency of pyridoxine results in impaired transcellular signaling...

Protocol for a prospective, observational, deep phenotyping study on adipose epigenetic...
https://doi.org/10.1136/bmjopen-2020-043644
BMJ Open; Nadiger N, Devi S et. al.

May 7th, 2021 - We describe the rationale and broad study design of the Indian Diabetes and Metabolic Health (InDiMeT) study, a new prospective, observational study incorporating extensive epigenetic (DNA methylation) and lipidomic signatures to examine their ass...

The association between insulin sensitivity indices, ECG findings and mortality: a 40-y...
https://doi.org/10.1186/s12933-021-01284-9
Cardiovascular Diabetology; Moshkovits Y, Rott D et. al.

May 7th, 2021 - Type 2 Diabetes is a major risk factor for cardiovascular (CV) mortality. Insulin resistance can be evaluated non-invasively by insulin sensitivity indices (ISI) such as the Mcauley index (MCAi), which is a function of the fasting insulin and trig...

Cost-Effectiveness of a Diabetes Self-Management Education and Support Intervention Led...
https://doi.org/10.2337/dc20-0307
Diabetes Care; Ye W, Kuo S et. al.

May 7th, 2021 - To simulate the long-term cost-effectiveness of a peer leader (PL)-led diabetes self-management support (DSMS) program following a structured community health worker (CHW)-led diabetes self-management education (DSME) program in reducing risks of ...

CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Pat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075672
Mediators of Inflammation; Li Y, Jin L et. al.

May 7th, 2021 - Few studies have illuminated the genetic role of T cell costimulatory molecule CD28/CD80/CTLA4 variants in diabetic kidney disease (DKD) susceptibility. We aimed to investigate the causal role of genetic polymorphisms in CD28/CD80/CTLA4 with DKD s...

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Guidelines  407 results

Draft Recommendation Statement: Screening for Prediabetes and Type 2 Diabetes Mellitus
https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/prediabetes-and-type-2-diabetes-mellitus-screening
US Preventative Services Task Force (USPSTF)

Mar 15th, 2021 - According to the Centers for Disease Control and Prevention’s (CDC’s) 2020 National Diabetes Statistics Report, an estimated 13% of all U.S. adults (age ≥18 years) have diabetes, and 34.5% meet criteria for prediabetes.1 The prevalence of prediabe...

Most COVID-19 hospitalizations due to four conditions
https://www.nih.gov/news-events/nih-research-matters/most-covid-19-hospitalizations-due-four-conditions
NIH Research Matters; National Institutes of Health (NIH)

Mar 8th, 2021 - Studies show that certain common medical conditions put people at higher risk for severe illness from COVID-19. These include metabolic disorders like type 2 diabetes and obesity, as well as heart conditions like high blood pressure (hypertension)...

Drug activates brown fat, improves glucose metabolism in healthy women
https://www.nih.gov/news-events/nih-research-matters/drug-activates-brown-fat-improves-glucose-metabolism-healthy-women
National Institutes of Health (NIH)

Feb 3rd, 2021 - The majority of adults in the U.S. carry too much fat in their bodies and are now considered overweight or obese. The last several decades have also seen a spike in related diseases of metabolism, such as type 2 diabetes.

Brown fat associated with less heart and metabolic disease
https://www.nih.gov/news-events/nih-research-matters/brown-fat-associated-less-heart-metabolic-disease
National Institutes of Health (NIH)

Feb 1st, 2021 - Too much white fat, a characteristic of obesity, has been shown to increase the risk of type 2 diabetes, high blood pressure, and other diseases. A less common type of fat, called brown fat, uses blood sugar and fat molecules to create heat and he...

Friend or foe? ACE2 inhibitors and GLP-1R agonists in COVID-19 treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785422/
Obesity Medicine; Pang J, Liu M et. al.

Jan 5th, 2021 - COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a pandemic since WHO made the statement on March 11, 2020. The infection is causing a high mortality in old people, especially those with obesity, type 2 di...

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Drugs  2,607 results see all →

Clinicaltrials.gov  125,619 results

Glimepiride - glimepiride tablet-Solco Healthcare U.S., LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=86acdd9e-8637-43e4-8bf7-b3a123b871b8

Aug 12th, 2021 - Glimepiride tablets USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies (14.1) ]. Limitations of Use Glimepiride tablets USP should not be used for the trea...

Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Dia...
https://doi.org/10.1016/j.amjms.2020.10.027
The American Journal of the Medical Sciences; Zhou J, Effiong U

May 7th, 2021 - Pyridoxine is an important co-factor for many biochemical reactions in cellular metabolism related to the synthesis and catabolism of amino acids, fatty acids, neurotransmitters. Deficiency of pyridoxine results in impaired transcellular signaling...

Protocol for a prospective, observational, deep phenotyping study on adipose epigenetic...
https://doi.org/10.1136/bmjopen-2020-043644
BMJ Open; Nadiger N, Devi S et. al.

May 7th, 2021 - We describe the rationale and broad study design of the Indian Diabetes and Metabolic Health (InDiMeT) study, a new prospective, observational study incorporating extensive epigenetic (DNA methylation) and lipidomic signatures to examine their ass...

The association between insulin sensitivity indices, ECG findings and mortality: a 40-y...
https://doi.org/10.1186/s12933-021-01284-9
Cardiovascular Diabetology; Moshkovits Y, Rott D et. al.

May 7th, 2021 - Type 2 Diabetes is a major risk factor for cardiovascular (CV) mortality. Insulin resistance can be evaluated non-invasively by insulin sensitivity indices (ISI) such as the Mcauley index (MCAi), which is a function of the fasting insulin and trig...

Cost-Effectiveness of a Diabetes Self-Management Education and Support Intervention Led...
https://doi.org/10.2337/dc20-0307
Diabetes Care; Ye W, Kuo S et. al.

May 7th, 2021 - To simulate the long-term cost-effectiveness of a peer leader (PL)-led diabetes self-management support (DSMS) program following a structured community health worker (CHW)-led diabetes self-management education (DSME) program in reducing risks of ...

see more →

News  9,627 results

FDA Blazes Path for 'Real-World' Evidence as Proof of Efficacy
https://www.medscape.com/viewarticle/950762

May 6th, 2021 - In 2016, results from the LEADER trial of liraglutide in patients with type 2 diabetes helped jumpstart awareness of the potential role of this new class of drugs, the glucagon-like peptide 1 (GLP-1) receptor agonists, for reducing cardiovascular ...

Could Cardiovascular Changes Predict Later Dementia in T2D?
https://www.medscape.com/viewarticle/950431

May 3rd, 2021 - Factors such as blood pressure, blood glucose levels, and cholesterol levels could predict the onset of dementia in individuals with type 2 diabetes up to 20 years beforehand, say UK researchers who hope the findings could help prevent or delay th...

Bariatric Surgery Least Favoured Route to T2D Remission
https://www.medscape.com/viewarticle/950167

Apr 28th, 2021 - Bariatric surgery may be the most effective method of achieving type 2 diabetes remission, but it is the least favoured, suggests the results of a debate in which experts weighed the pros and cons of the main approaches. However, no matter whether...

Promising Data on Once-Weekly Insulin, Phase 3 Study Ongoing
https://www.medscape.com/viewarticle/949924

Apr 25th, 2021 - Two new phase 2 studies show encouraging findings with the investigational once-weekly basal insulin analogue icodec (Novo Nordisk) for people with type 2 diabetes who require insulin. Insulin icodec works by reversibly binding to albumin, which s...

Pros and Cons of Draft Recommendations for Prediabetes, Diabetes Screening
https://www.medscape.com/viewarticle/949991

Apr 25th, 2021 - Dr Santina J. G. Wheat The United States Preventive Services Task Force recently released a draft of updated recommendations for screening for prediabetes and type 2 diabetes mellitus (DM). If accepted as written, the new recommendation will be to...

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Patient Education  81 results see all →